Current News & Archives 2018

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2018

SUCCESS STORY
Top-down Proteomics
CBC Senior Investigator, Neil Kelleher, NU, explains the advantages of “top-down” versus “bottom-up” proteomics in early cancer detection and progression
Neil Kelleher, NU, received a CBC Recruitment Resources Award (2010) and hence is recognized as a CBC Senior Investigator. Kelleher’s other ties to CBC are described following the article.
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August 9, 2018
SUCCESS STORY
Synthetic biology wins NIH support
CBC affiliate, Josh Leonard, NU, a co-PI on an NIH grant for a project in the interdisciplinary field of synthetic biology
Josh Leonard, NU, received a CBC Catalyst Award (2017) and was an invited speaker at the 9th Annual CBC Symposium.
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August 8, 2018
SUCCESS STORY
Lisagor Award 2018
CBC affiliate and evolutionary biologist, Marcus Kronforst, UChicago, recognized with a Lisagor Award for his educational work on Chicago PBS series, ‘Urban Nature’
Marcus Kronforst and his postdoc, Erica Westerman, UChicago, received a CBC Postdoctoral Research Award (2014).
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August 8, 2018
SUCCESS STORY
Tick, tock, tick, tock
Michael Rust, UChicago, who has many ties to CBC, explains two types of circadian “clocks”
Michael Rust, UChicago, received a CBC Catalyst Award (2016) and a CBC Postdoctoral Research Award (2014). In 2011, by receiving a CBC Recruitment Resources Award, Rust became a CBC Junior Investigator. In addition, since 2017, he has served on the CBC Catalyst Review Board.
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August 8, 2018
SUCCESS STORY
Iron, heart and mitochondria
Two CBC affiliates, Hossein Ardehali and Paul Schumacker, NU, investigate how the heart copes with iron deficiency
Hossein Ardehali and Paul Schumacker, NU, received a CBC Catalyst Award in 2007. Schumacker received a second CBC Catalyst Award in 2009.
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August 6, 2018
News
CBCAN August 2, 2018 – a recap
CBC Accelerator Network (CBCAN) meeting: Accelerator Award proposals Round Two, Part One
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August 3, 2018
SUCCESS STORY
2018 Young Investigator Award
CBC affiliate, Michael Jewett, NU, wins the 2018 Young Investigator Award
Michael Jewett, NU, was a recipient of a CBC Catalyst Award (2013), a speaker at the CBC Scholars “Loop Connections” Seminar (2013) and at the 12th CBC Annual Symposium (2014), and has been serving on the CBC Catalyst Award Review Board (CRB) since 2016.
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August 3, 2018
“in the news”
FSG helps CBC better understand its transition into Phase 2
Strategic evaluation of the CBC with the consulting group FSG
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August 1, 2018
SUCCESS STORY
Inaugural Trailblazer Prize
CBC Affiliate, Jaehyuk Choi, NU, among finalists of FNIH’s 2018 Trailblazer Prize for Clinician-Scientists
Jaehyuk Choi, NU, is a recipient of a CBC Catalyst Award (2017)
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August 1, 2018
SUCCESS STORY
The circle of accomplices in CVDs just got wider
Mapping genome-wide interactions between enhancers and their target genes in cardiovascular diseases (CVDs) — past CBC awardee Elizabeth McNally, NU, contributes
Elizabeth McNally, NU, received two CBC Awards: a Catalyst (2007) and a Spark (2008).
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August 1, 2018
SUCCESS STORY
2018 McKnight Awards
CBC past awardee, Marco Gallio, NU, receives 2018 McKnight Technological Innovation in Neuroscience Award
Marco Gallio, NU, together with a postdoc in his lab, Emanuela Zaharieva, received a CBC Postdoctoral Research Award (2014).
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July 24, 2018
SUCCESS STORY
Test tube glycoproteins
A powerful new technology combining cell-free protein synthesis with protein glycosylation in “one-pot” developed with help of two NU researchers with ties to CBC, Michael Jewett and Milan Mrksich
Michael Jewett and Milan Mrksich, NU, have multiple ties to CBC (see the article for the details).
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July 24, 2018
SUCCESS STORY
Problems with CRISPR
CBC past awardee and CBC Tech Day speaker, Brad Merrill, UIC, discovers a mechanism behind CRISPR gene editing imperfection
Brad Merrill, UIC, received a CBC Catalyst Award (2014), was an invited speaker at the CBC Tech Day (2014) and was a mentor to a CBC Scholar, Brian Shy, Class of 2013.
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July 19, 2018
SUCCESS STORY
Understanding slippery surfaces
Matt Tirrell, UChicago, a twice CBC awardee, explains
Matt Tirrell, UChicago, received a CBC Catalyst Award (2013) and a CBC Postdoctoral Research Award (PDR, 2014).
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July 18, 2018
SUCCESS STORY
A Nano Research Award 2018
…goes to Chad Mirkin, NU, a past CBC Lever Award co-recipient!

Chad Mirkin, NU, received a CBC Lever Award (2011).
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July 18, 2018
SUCCESS STORY
Mimicking the master of camouflage
Teri Odom, a NU scientist with links to CBC, builds a nanolaser that changes colors using a molecular mechanism similar to the one found in the chameleon’s skin
Teri Odom, NU, received funding for a Pilot Project through the CBC Lever Award (2015).
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July 8, 2018
CBC Newsletter, Vol. 25
CBC Announces New Funding, Educational and Networking Opportunities
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July 2, 2018
SUCCESS STORY
TWIK-ing inflammation
Two UIC scientists with links to CBC, Asrar Malik and Jalees Rehman, identify a new potassium channel crucial for activating inflammation
Asrar Malik and his two postdocs, UIC, received CBC Postdoctoral Awards (2014 and 2016) and Jalees Rehman, UIC, was a CBC Catalyst Award recipient (2011).
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July 2, 2018
SUCCESS STORY
Monitor displays made of DNA?
A paradigm-shifting photo-optic properties of nanoparticles made of synthetic DNA crystalline lattices — past CBC Lever awardee Chad Mirkin, NU, explains
Chad Mirkin, NU, is a CBC Lever awardee (2011).
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July 2, 2018
SUCCESS STORY
Potential Parkinson’s disease treatment on the horizon
Past CBC awardee, Paul Schumacker, NU, contributes to pre-clinical evaluation of israpidine’s neuroprotective effect on dopaminergic neurons that are affected by Parkinson’s disease
Paul Schumacker, NU, is a twice CBC Catalyst awardee (2007 and 2009).
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June 29, 2018
DIRECTOR’S CORNER
Changes in FDA’s Approach to Predictive Toxicology
By Jim Audia
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June 27, 2018
SUCCESS STORY
KBU2046—new compound that inhibits cancer cell motility
Four current and one past NU scientists with ties to CBC contribute to the publication: Karl Scheidt, Andrew Mazar, Wayne Anderson, Sankar Krishna and Raymond Bergan (now at OHSU)
NU scientists, Karl Scheidt, Andrew Mazar, Wayne Anderson, Sankar Krishna and Raymond Bergan (now at OHSU), have multiple ties to CBC (see the article for details).
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June 27, 2018
SUCCESS STORY
Ketamine, lipid rafts, and depression
Past CBC Scholars Colloquium speaker, Mark Rasenick, UIC, investigates the mechanisms for antidepressant effects of ketamine
Mark Rasenick, UIC, was an invited speaker at the CBC Scholars Colloquium (2012).
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June 27, 2018
SUCCESS STORY
Ver Steeg Fellows 2018 named
CBC community member Susan Quaggin, NU, receives prestigious Ver Steeg Fellowship
Susan Quaggin, NU, was a co-organizer of a CBC Exploratory Workshop (2014).
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June 25, 2018
News
CBC welcomes Dr. Luisa DiPietro as Scientific Director for UIC
Dr. DiPietro joins the CBC leadership as successor to Dr. Brian Kay who served in the role since 2011
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June 25, 2018
News
CBCAN June 21, 2018 – a recap
Core facilities and the Open Access Initiative at CBC Institutions: History, progress and gaps discussed at CBCAN
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June 20, 2018
“in the news”
CBC welcomes Deerfield to the healthcare community in Chicago during the Lakeside Discovery launch event
CBC Executive Director Jim Audia to serve as a Lakeside Discovery Joint Steering Committee member
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June 18, 2018
SUCCESS STORY
A wound-healing bandage
Multiple CBC awardees, Guillermo Ameer and Milan Mrksich, NU, develop new regenerative bandage that speeds up diabetic wound healing.
Guillermo Ameer and Milan Mrksich, NU, received several CBC awards and have multiple other ties to CBC (for details see the article).
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June 18, 2018
SUCCESS STORY
Understanding cardiac metabolism
Past CBC Catalyst Award recipient, Hossein Ardehali, NU, deciphers the role that mitochondria play in the heart
Hossein Ardehali, NU, received a CBC Catalyst Award (2007).
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June 15, 2018
News
Deerfield comes to Chicago
CBC excited to support Lakeside Discovery, a partnership between Northwestern University and Deerfield Management
CBC Executive Director Jim Audia joins the Lakeside Discovery Joint Steering Committee
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June 14, 2018
SUCCESS STORY
A swimmer’s gut
CBC awardee, Rachel Poretsky, UIC, is looking into the cause-effect correlations between the athletic gut microflora and the athlete’s performance
Rachel Poretsky is a co-recipient of a CBC Catalyst Award (2014) and a CBC Postdoctoral Research Award (2015).
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June 14, 2018
SUCCESS STORY
Specific organ-tropic bacteria could augment cancer immunotherapy
CBC awardee, Sarki Abdulkadir, NU, co-senior author on a recent Nature Communications publication
Sarki Abdulkadir, NU, is a recipient of a CBC Catalyst Award (2018).
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June 13, 2018
SUCCESS STORY
Nancy Freitag, UIC, the New Vice Provost for Faculty Affairs
Nancy Freitag, UIC, has served on the CBC Catalyst Review Board (2015-present) and is a past recipient of a CBC Postdoctoral Research Award (2016) and a CBC Catalyst Award (2014), and, in 2015, helped organize the 13th Annual CBC Symposium (2015).
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June 13, 2018
SUCCESS STORY
NU bioengineer, entrepreneur and past CBC awardee, Guillermo Ameer, to lead the new Center for Advanced Regenerative Engineering (CARE)
Guillermo Ameer, NU, received three Postdoctoral Research Awards (one in 2015, and two in 2014) and a Catalyst (2013). His company, VesselTek Biomedical, won a CBC Business Plan Competition (2009). He also spoke at the inaugural CBCAN meeting (2017).
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June 12, 2018
SUCCESS STORY
Combining immunotherapy with bacterial applications to treat certain cancers — twice a CBC awardee Thomas Gajewski, UChicago, comments for Nature
Thomas Gajewski, UChicago, received two CBC Awards: a Catalyst Award (2013) and a Postdoctoral Research Award (2014).
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June 8, 2018
SUCCESS STORY
How do young brains differ from the old ones? Octopus brains from those of the mice? Healthy from the mentally challenged? A CBC awardee, Bobby Kasthuri, UChicago, wants to know
Narayanan (Bobby) Kasthuri, UChicago, received a CBC Catalyst Award (2017). Clifton Ragsdale, UChicago, was a mentor to Joanna Rowell, a CBC Scholar, Class of 2012(2012-2013).
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June 8, 2018
SUCCESS STORY
CBC Junior Investigator, Sadie Wignall, NU — a cell biologist featured by the American Society for Cell Biology
Sadie Wignall, NU, is a CBC Junior Investigator (CBC Recruitment Resources Award, 2011). Sadie received a CBC Catalyst Award (2016) has since served on the CBC Catalyst Review Board (2016-2017).
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June 5, 2018
SUCCESS STORY
NSF-Simons Center for Quantitative Biology at Northwestern to be led by researchers with ties to CBC, Richard Carthew and William Kath
Richard Carthew, NU, received a CBC Catalyst Award (2006) and was a speaker at two CBC annual symposia (2005 & 2009). Carthew and William Kath, also from NU, were mentors to three CBC Scholars.
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June 4, 2018
DIRECTOR’S CORNER
Modernization effort at FDA’s Center for Drug Evaluation and Research (CDER)
By Jim Audia
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June 3, 2018
News
CBC announces Round One Accelerator Award proposals deemed eligible for funding
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June 1, 2018
SUCCESS STORY
A ‘Trojan Horse’ approach to killing cancer cells — explained by past CBC awardee and board member, Tom O’Halloran, NU
Tom O’Halloran, NU, received a CBC Spark Award (2009), served on several CBC boards and more recently, participated as panelist in the CBC Accelerator Network (CBCAN) meeting (2017).
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June 1, 2018
SUCCESS STORY
Malfunctioning synaptic vesicles may contribute to Parkinson’s Disease — a CBC Catalyst awardee, Dimitri Krainc, NU, reports
Dimitri Krainc, NU, is a co-recipient of a CBC Catalyst Award (2017).
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May 24, 2018
SUCCESS STORY
Past CBC awardee, Bozhi Tian, UChicago, speaks about his career and his newest research for the journal Nature
Bozhi Tian with his postdoctoral fellow, Yucai Wang, UChicago, received a CBC Postdoctoral Research Award (2014).
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May 24, 2018
SUCCESS STORY
From gut to blood to cancer—CBC scientists, Lucy Godley and Eugene Chang, UChicago, provide new insights into the mechanism of TET2-linked leukemia development
CBC Scientific Director for UChicago, Lucy Godley, and past CBC awardee (2015 CBC Catalyst Award), Eugene Chang, also from UChicago, contributed to the published research.
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May 23, 2018
SUCCESS STORY
Past CBC awardee and frequent CBC board contributor, Kathleen Green, NU, honored with the David Martin Carter Mentor Award
Kathleen Green (NU) is co-recipient of two CBC Postdoctoral Research Awards (in 2014 and 2015, respectively). She also served on both the CBC Spark Award Council and Review Panel as well as on the CBC Catalyst Review Board.
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May 22, 2018
SUCCESS STORY
“Oligometastasis,” or a cancer that has metastasized but just to a few sites, not globally, is still treatable. CBC Senior Investigator, Kevin White, UChicago, contributes to the discovery.
Kevin White (UChicago) received a CBC Recruitment Resources Award (2006) and CBC Lever Award (2008). He has also served on two CBC boards and spoke at the CBC Annual Symposium (2006) and CBC Science Day (2011) (see text for details).
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May 22, 2018
SUCCESS STORY
CBC awardee Joshua Leonard, NU, receives a 2018 Charles Deering McCormick Professor of Teaching Excellence award
Joshua Leonard (NU) received a CBC Catalyst Award (2017), was an invited speaker at the 9th CBC Annual Symposium (2011), and was a mentor to a CBC Scholar Andrew Scarpelli, NU, Class of 2012 (2012-2013).
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May 22, 2018
DIRECTOR’S CORNER
Medicinal chemistry (or drug discovery more generally) is hard. Some guidance for making it possible.
By Jim Audia
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May 18, 2018
SUCCESS STORY
CBC multiple awardee Chuan He, UChicago, with the science behind Accent Therapeutics, a new biotech company that just launched with a $40 million investment
Chuan He (UChicago) has been a very active and productive CBC member (see the article for the details).
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May 17, 2018
SUCCESS STORY
Mapping the entire human brain – a dream that may come through for the UChicago scientist and current CBC awardee, Narayanan (Bobby) Kasthuri
Narayanan (Bobby) Kasthuri (UChicago) received a CBC Catalyst Award (2017).
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May 17, 2018
SUCCESS STORY
Metarrestin, a novel compound with anti-metastatic properties. Two NU researchers with ties to CBC, Irawati (Angki) Kandela and Andrew Mazar, participated in the discovery.
Irawati (Angki) Kandela (NU) was a CBC nominee and now a winner of a Student Award to attend 2018 Drug Safety Gordon Research Conference. Andrew Mazar (NU) was a panel moderator in the CBC Tech Day (2012).
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May 15, 2018
News
Five Student Awards made to the CBC members to attend the 2018 Drug Safety Gordon Research Conference
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May 15, 2018
SUCCESS STORY
Restoring neuronal levels of intracellular chloride to normal in an animal model of autism prevents the occurrence of hyper-excitability. Past CBC awardee, Jeffrey Savas, NU, contributes to the published research.
Jeffrey Savas, NU, who has contributed to the published research, is a recipient of a 2015 CBC Catalyst Award.
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May 15, 2018
SUCCESS STORY
Two heads are better than one: joining forces, two NU researchers and past CBC awardees, Milan Mrksich and Michael Jewett, develop GlycoSCORES, a new glycoprotein screening technique.
Milan Mrksich and Michael Jewett have many links to CBC: both received CBC awards in the past (for details see the article), participated in many CBC-organized educational events and served on CBC boards, with Jewett currently serving on the CBC Catalyst Award Review Board (2016-present).
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May 14, 2018
DIRECTOR’S CORNER
Precision Medicine ‘Of the people, for the people, by the people’?
By Jim Audia
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May 14, 2018
“in the news”
NewCures to strengthen the portfolio of Chicago-area biomedical development programs, such as CBC and NCAI-CC
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May 11, 2018
SUCCESS STORY
Spotlight on a CBC community member, Julian Solway, UChicago, a co-PI on a $35 million grant from the NIH, to support the Institute for Translational Medicine
Julian Solway, UChicago, was an invited speaker at the CBC Exploratory Workshop on Cellular Heterogeneity (2013).
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May 11, 2018
SUCCESS STORY
2018 Order of Lincoln Award bestowed on Dr. Louis Philipson, Professor of Medicine at UChicago and past CBC Spark Award recipient
Louis Philipson, UChicago, is a 2011 CBC Spark Award co-recipient.
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May 10, 2018
News
“On the Table” Lunch hosted by the Chicago Biomedical Consortium
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May 9, 2018
SUCCESS STORY
“Smellovision” explained. An interview with a CBC Junior Investigator, Daniel Dombeck, NU
Daniel Dombeck is a CBC Junior Investigator who was hired by NU in 2011 with a help of a CBC Recruitment Resources Award. He is also a member of the CBC Catalyst Review Board.
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May 9, 2018
SUCCESS STORY
Prestigious honors bestowed on three CBC community members: Joy Bergelson, UChicago; and Maciej Lesniak and Hossein Ardehali, NU
Joy Bergelson (UChicago), served on the CBC Recruitment Resources Fund Board (2010-2012); Matt Lesniak (NU) and his postdocs received three CBC Postdoctoral Research Awards (2014, 2015 and 2016) and Hossein Ardehali (NU) was a recipient of 2008 Catalyst Award.
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May 9, 2018
SUCCESS STORY
Genetic testing in hematologic malignancies – an interview with CBC Scientific Director for UChicago, Lucy Godley, and other experts in the field
Bozhi Tian (UChicago), received a CBC Postdoctoral Research Award (2014). Lucy Godley (UChicago), is CBC Scientific Director for UChicago.
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May 8, 2018
CBC Newsletter, Vol. 25
CBC Announces New Funding, Educational and Networking Opportunities
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May 8, 2018
SUCCESS STORY
Shining light on silicon — two UChicago researchers with ties to CBC, Bozhi Tian and Chin-Tu Chen, demonstrate that optically-controlled silicon nanowires can influence behavior
Bozhi Tian (UChicago), received a CBC Postdoctoral Research Award (2014). Chin-Tu Chen (UChicago), received a CBC Postdoctoral Research Award (2015), was an invited speaker at the 6th Annual CBC Symposium (2008) and served on the CBC Spark Review Panel.
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May 3, 2018
SUCCESS STORY
The Genomic Data Commons explained. Past CBC awardee, Bob Grossman, UChicago discusses the power and promise of creating data commons to globally and collaboratively accelerate biomedical research
Robert (Bob) Grossman, UChicago, is a co-recipient of a CBC Lever Award (2008).
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May 3, 2018
SUCCESS STORY
Give up something to gain something… and how it applies to a multi-chamber device that may help preserve biological structures against damage by electron microscopy. Spotlight on past CBC awardee, Tolou Shokuhfar, UIC.
Tolou Shokuhfar, UIC, together with a postdoc in her lab, Emre Firlar, received a CBC Postdoctoral Research Award (2016).
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May 2, 2018
SUCCESS STORY
Exploiting elevated metabolism in prostate cancer cells as a weakness — a new potential therapeutic approach successfully explored by a two time CBC award winner, Nissim Hay, UIC
Nissim Hay, UIC, received a CBC Catalyst (2007) and a CBC Spark (2011) Awards, and presented his research at the CBC Tech Day (2014).
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May 2, 2018
SUCCESS STORY
Past CBC Spark Award recipient, Vinayak Dravid, NU, contributes to the development of an inexpensive semiconductor capable of effectively detecting gamma-rays; a next-generation nuclear radiation detector?
Vinayak Dravid, NU, was a co-recipient of a CBC Spark Award (2009).
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April 27, 2018
SUCCESS STORY
Could an ancient bacterial toxin, once integrated into a multicellular organism, have evolved into adhesion molecules that guide neuronal development and function? A story of teneurins, by a twice CBC awardee, Demet Araç-Özkan, UChicago
Demet Araç-Özkan, UChicago received CBC HTS and CBC Postdoctoral Research Awards, both in 2016.
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April 27, 2018
SUCCESS STORY
UIC scientist with ties to CBC, Yulia Komarova, contributes to a study on how human cytomegalovirus (HCMV) hijacks microtubules to form an intracellular virus maturation compartment
Yulia Komarova (UIC) is a Spring 2018 CBC Accelerator Award finalist.
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April 27, 2018
SUCCESS STORY
On leanness and obesity-promoting microbiota, and on positive feedback loops — Eugene Chang, UChicago researcher and CBC past awardee
Eugene Chang, and one of co-authors, Catherine Reardon, both from UChicago, are past CBC awardees. Reardon was awarded in 2013 to organize a CBC Exploratory Workshop; in 2015, Chang received a CBC Catalyst Award.
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April 25, 2018
SUCCESS STORY
Using ‘top-down proteomics, CBC Senior Investigator, Neil Kelleher, NU, identifies and precisely measures eleven KRAS oncogene proteoforms found in colon cancer cells
Neil Kelleher (NU), is CBC Senior Investigator (2010), recipient of a CBC Catalyst Award (2010), and has participated in several CBC-organized events (see the full story). He is also Director of the NU Proteomics Center of Excellence which was established with CBC support.
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April 25, 2018
SUCCESS STORY
Past CBC awardee, Patric Kiser, NU, elected to the American Institute for Medical and Biological Engineering’s College of Fellows
Patric Kiser (NU), together with a postdoc in his lab, Arangassery Rosemary Bastian, received a CBC Postdoctoral Research Award (2015).
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April 25, 2018
SUCCESS STORY
Past CBC symposium speaker, Melody Swartz, UChicago, elected to American Academy of Arts and Sciences
Melody Swartz (UChicago) was an invited speaker at the 9th Annual CBC Symposium (2011).
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April 25, 2018
SUCCESS STORY
New genetic screen developed by past CBC awardee, Balaji Manicassamy, UChicago, identifies genes involved in the influenza virus infection
Balaji Manicassamy (UChicago) received a CBC Catalyst Award (2014).
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April 20, 2018
News
Early Stage Regulatory Guidance on the Pathway to an IND discussed at April 19 CBCAN
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April 13, 2018
News
CBC Executive Director Jim Audia presents his vision for CBC Phase 2 at the iBIO Board meeting
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April 13, 2018
“in the news”
The very first of the CBC Phase 2 initiatives — the CBC Accelerator Network (CBCAN) — recognized among “Illinois’ Growing Startup Resources”!
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April 13, 2018
SUCCESS STORY
Past CBC awardee and frequent presenter at CBC-organized events, Rick Silverman, NU, highlighted in the journal Science, for his work to develop novel anti-addiction drugs
Rick Silverman (NU) received a CBC HTS Award (2015) and presented at two Annual CBC Symposia (2013 and 2017), and at the CBC Tech Day (2013).
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April 11, 2018
SUCCESS STORY
Two CBC awardees, Bryan Dickinson and Raymond Moellering, featured in the UChicago Medicine Comprehensive Cancer Center 2017 Annual Report: Powered by Innovation
Bryan Dickinson (UChicago) received a CBC Catalyst Award (2016). Raymond Moellering (UChicago) received a CBC Catalyst Award (2017), currently serves on the CBC Accelerator Review Board, and was an invited speaker at the 15th Annual CBC Symposium (2017).
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April 11, 2018
SUCCESS STORY
Why is epilepsy so common in autism? A CBC affiliate, Peter Penzes, NU, discovers how mutated Cntnap2 may destabilize inhibitory neuronal connections in the autistic brain.
Peter Penzes (NU), was an invited speaker at the 14th Annual CBC Symposium (2016).
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April 10, 2018
SUCCESS STORY
Understanding the pathogenesis of atrial fibrillation (AFib) in the Latino population — a CBC Awardee, Jalees Rehman, UIC, contributes to the story.
Jalees Rehman (UIC) received a CBC Catalyst Award in 2009.
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April 6, 2018
SUCCESS STORY
UIC collaborates with a French biotech company to reveal the mechanism of action of recently discovered antibiotics. Past CBC awardee, Alexander Mankin, UIC, in the spotlight.
Alexander Mankin (UIC), is a past CBC awardee (Spark Award, 2009). He also served on a Spark Review Panel and was an invited speaker at the 7th CBC Annual Symposium (2009).
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April 5, 2018
SUCCESS STORY
A CBC affiliate Peter Penzes, NU, discusses the genetics and neurobiology of autism
Peter Penzes, NU, was an invited speaker at the 14th Annual CBC Symposium (2016).
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March 29, 2018
DIRECTOR’S CORNER
A rising tide: Chicago biomedical research institutions to receive increased NIH funding in 2018
By Jola Glotzer
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March 28, 2018
SUCCESS STORY
A cross-road between brain inflammation and seizures. Past CBC affiliate, Stephen Miller, NU, explains.
Stephen Miller (NU) served in the past on the CBC Spark Review Panel.
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March 28, 2018
SUCCESS STORY
In 2006, CBC invested $1 million to help recruit Kevin White to UChicago. Twelve years later, White is president of Tempus, a Chicago-based health technology company, that has now reached ‘unicorn’ status!
Kevin White (UChicago) received a CBC Recruitment Resources Award (2006) and CBC Lever Award (2008). He has also served on two CBC boards and spoke at the CBC Annual Symposium (2006) and CBC Science Day (2011) (see text for details).
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March 28, 2018
SUCCESS STORY
New insights into the mechanism of methane metabolism by copper-binding bacteria revealed in a study from the Rosenzweig lab and CBC Senior Investigator, Neil Kelleher, NU
Publication attributed to a CBC Recruitment Award (2010) to Neil Kelleher (NU). Amy Rosenzweig (NU) is a recipient of a CBC Postdoctoral Research Award (2016) and Kelleher of a CBC Catalyst Award (2010). Kelleher and Paul Thomas, both members of the NU Proteomics Center of Excellence which was established with CBC support, participated in several CBC-organized events (see text for details).
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March 26, 2018
SUCCESS STORY
New, cell-free protein manufacturing methodology, developed by Michael Jewett’s NU team and supported by CBC funding, could have important implications in biomedicine and beyond
Publication attributed to a CBC Catalyst Award (2013) to Michael Jewett, NU. Other co-authors, Neil Kelleher, Roderick Davis and Paul Thomas, NU received multiple CBC awards and participated in many CBC-organized events (see text for details).
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March 23, 2018
SUCCESS STORY
TTC-352, a new breast cancer agent developed by Debra Tonetti and Greg Thatcher, UIC, may become a therapeutic for patients with estrogen receptor-positive breast cancer that expresses specific biomarkers
Debra Tonetti and Greg Thatcher (UIC) received multiple CBC awards, participated in many CBC-organized events and served on CBC Boards (see text for details).
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March 23, 2018
SUCCESS STORY
UIC research team with links to CBC awarded $2.7 million NIH grant to study the lung microbiome, immune system, and their roles in the lung inflammatory disease, sarcoidosis
Yang Dai (UIC) is a co-recipient of a CBC Catalyst Award (2009).
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March 23, 2018
SUCCESS STORY
Can a phone ‘read’ your mood? BiAffect app developers, Dr. Alex Leow and a past CBC awardee, Peter Nelson, UIC, explain.
Peter Nelson (UIC) received a CBC Catalyst Award (2006).
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March 22, 2018
SUCCESS STORY
Spotlight on a NU neurosurgeon and triple CBC awardee, Maciej Lesniak, and his quest to treat glioblastoma… without a knife
Maciej Lesniak (NU) and three of his postdocs have received CBC Postdoctoral Research Awards.
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March 16, 2018
SUCCESS STORY
The promise of increased sensitivity for early cancer detection and management being realized by Vadim Backman and Tom O’Halloran, NU, with the help of instrumentation and a core facility supported by a CBC Lever Award
Vadim Backman, NU is co-recipient of a CBC Lever Award (2015). Tom O’Halloran’s (NU) many ties to CBC are listed below the article.
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March 15, 2018
SUCCESS STORY
Fluidigm CyTOF-2 Mass Cytometer, hosted by the lab of a past member of the CBC Catalyst Review Board, Anne Sperling, UChicago, helps in study of idiopathic pulmonary fibrosis (IPF)
Anne Sperling, UChicago, served on the CBC Catalyst Review Board (2013-2017).
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March 15, 2018
SUCCESS STORY
CRISPR then, now and in the future — three current and past NU scientists with multiple links to CBC: Elizabeth McNally, Navdeep Chandel and Eric Sontheimer
Elizabeth McNally (NU), Navdeep Chandel (NU) and Eric Sontheimer (UMMS, at NU then) have multiple links to CBC (listed after the article).
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March 15, 2018
SUCCESS STORY
The National Institute of Environmental Health Sciences grant will support UIC scientists, including CBC community member, Dr. Brian Layden, in their effort to decipher the mechanisms of arsenic-induced diabetes
Brian Layden, UIC, is a CBC Accelerator Review Board member.
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March 14, 2018
SUCCESS STORY
On nanowires helping neurons do their job — featuring the Tian lab, UChicago
Bozhi Tian, UChicago, is a past CBC Postdoctoral Research Award (2014) recipient. A co-author on the paper, John Zimmerman, was a graduate student at the Tian lab and a CBC Scholar, Class of 2014.
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March 14, 2018
SUCCESS STORY
You are such a bird-brain! Tracing intelligence of birds and alligators demonstrates that a “bird-brain” phrase may be obsolete.
Joanna Rowell was a CBC Scholar, Class of 2012.
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March 13, 2018
SUCCESS STORY
The power of cancer prevention — a spotlight on Dr. Lucy Godley, CBC Scientific Director, UChicago
Dr. Lucy Godley is a CBC Scientific Director for UChicago.
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March 13, 2018
DIRECTOR’S CORNER
Connecting with my past and celebrating the chemistry of the future at the Lilly Grantee Symposium
By Jim Audia
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March 9, 2018
SUCCESS STORY
A past CBC awardee and community member, Wonhwa Cho, UIC, becomes the inaugural UIC LAS Endowed Chair in the Sciences
Wonhwa Cho, UIC, received two CBC Catalyst Awards (2007 and 2010), served at the CBC Scientific Review Board and was an invited speaker at the CBC Microscopy Forum (2009).
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March 8, 2018
SUCCESS STORY
Stefan Kathman, a CBC Scholar, Class of 2014, continues his scientific training at The Scripps Research Institute
Stefan Kathman (The Scripps Research Institute; at NU at the time of the award) received the CBC Scholar Award (2014-2015).
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March 8, 2018
DIRECTOR’S CORNER
How not to do it? Mastering (or not) the hyperbole
By Jim Audia
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March 7, 2018
SUCCESS STORY
Following a “weather forecast for the flu” may help contain the spread in the U.S. – predicts a CBC community member and a past CBC awardee, Andrey Rzhetsky
Andrey Rzhetsky, UChicago, was a co-recipient of a CBC Lever Award (2011), served on both, CBC Scientific Review Board and CBC Spark Review Panel, and helped organize the 14th CBC Annual Symposium.
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March 6, 2018
SUCCESS STORY
On ‘smellovision’ and ‘olfactory virtual reality’ – a CBC Junior Investigator, Daniel Dombeck, NU, explains
Daniel Dombeck is a CBC Junior Investigator who was hired by NU in 2011 with a help of a CBC Recruitment Resources Award. He is also a member of the CBC Catalyst Review Board.
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March 6, 2018
SUCCESS STORY
A CBC awardee Eugene Chang, UChicago, contributes his expertise into a discussion about the causes and treatment of IBD and other gut imbalances
Eugene Chang, UChicago, is a CBC Catalyst Award (2015) recipient.
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March 5, 2018
SUCCESS STORY
A CBC community member, Christian Peterson, NU, receives the 2018 Elizabeth D. Hay New Investigator Award from the Society for Developmental Biology
Christian Peterson, NU, was an invited speaker at the CBC Scholars “Loop Connections” Colloquium (2012).
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March 5, 2018
SUCCESS STORY
Could wires help re-wire brain’s neuronal circuits? A new technique to modulate neuronal conductivity developed in the Tian lab, UChicago
Bozhi Tian, UChicago, is a past CBC Postdoctoral Research Award (2014) recipient. A co-author on the paper, John Zimmerman, was a graduate student at the Tian lab and a CBC Scholar, class of 2014.
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March 5, 2018
DIRECTOR’S CORNER
More recognition for Chicago, role of local universities in the startup community
By Jim Audia
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February 27, 2018
SUCCESS STORY
A story of Apollo and Artemis, a single gene that duplicated and evolved to drive opposite sex-specific reproductive functions in Drosophila males and females—a CBC awardee, Manyuan Long, UChicago, reports
Manyuan Long (UChicago) is a three-times CBC Award recipient of a Catalyst (2007), a Spark (2009) and a Postdoctoral Research (2014) Awards. Long was also an invited speaker at the 7th Annual CBC Symposium (2009).
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February 27, 2018
SUCCESS STORY
A CBC Lever Award recipient, Bob Grossman, UChicago, to build Pediatric Cancer Data Commons
Bob Grossman (UChicago) is a co-recipient of a CBC Lever Award (2008).
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February 26, 2018
SUCCESS STORY
Spotlight on two CBC-supported NU facilities that have helped develop a promising new delivery system for sustained-release of therapeutics
The Structural Biology Facility (NU) hosts a Gatan K2 direct electron detector, which was purchased by NU with the funds from the CBC Infrastructure Initiative (2014). Center for Advanced Molecular Imaging (CAMI), was initially partially funded through the CBC Spark Award (2009).
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February 23, 2018
DIRECTOR’S CORNER
Evolving FDA guidance for developing early Alzheimer’s Disease therapeutics
By Jim Audia
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February 22, 2018
NEWS
Fall 2017 Round Catalyst Awards Announced
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February 22, 2018
SUCCESS STORY
What causes one disease may cure another—two NU scientists and CBC community members, Marcus Peter and Shad Thaxton, collaborate to develop a potent cancer treatment
Marcus Peter (NU) was an invited speaker at a 2013 CBC Exploratory Workshop; Shad Thaxton (NU) and a postdoc in his lab, Linda Foid, received a 2014 CBC Postdoctoral Research Award.
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February 14, 2018
SUCCESS STORY
Tricking bacteria to remain non-hostile may become a method of choice in preventive medicine—the Federle lab at UIC shows how
Michael Federle (UIC) and Tiara Pérez Morales (at UIC at time of the award) received a CBC High-throughput Screening Award (2015) which was used to partially support the publication. Numerous other links to CBC for Federle and Kiira Ratia, also a co-author on the publication, are listed.
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February 13, 2018
DIRECTOR’S CORNER
What do we mean by ‘discharging translational risk’?
By Jim Audia
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February 13, 2018
NEWS
Celebrating the 2000th publication resulting from CBC funding—Jia Chen and Rich Longnecker (NU) with the milestone paper
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February 13, 2018
SUCCESS STORY
CBC-sponsored researchers discover a potential Epstein–Barr virus (EBV) receptor—the Longnecker lab, NU, in a spotlight
Richard Longnecker and his postdoc, Jia Chen, NU, received a CBC Postdoctoral Research Award in 2014, subsequently renewed for 2015.
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February 12, 2018
NEWS
CBC Accelerator Network (CBCAN) meeting: Accelerator Award proposals round one, part 2
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February 8, 2018
DIRECTOR’S CORNER
Analyzing the Past to Predict the Future of Pharmaceutical R&D
By Jim Audia
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February 7, 2018
“in the news”
CBC, MATTER and CIM@MATTER recognized as “accelerator programs to turn research into start-up” in Chicago area
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February 7, 2018
DIRECTOR’S CORNER
Design Principles for Building an Entrepreneurial Ecosystem
By Jim Audia
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February 2, 2018
NEWS
CBC Accelerator Network (CBCAN) meeting: Accelerator Award proposals round one, part 1
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February 2, 2018
SUCCESS STORY
Awards keep pouring in for the past CBC Lever awardee, Chad Mirkin, NU—congratulations on the prestigious 2018 Nano Research Award!
Chad Mirkin, NU, was a co-recipient of a CBC Lever Award (2010).
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February 2, 2018
SUCCESS STORY
New therapeutic opportunities open up for congenital glaucoma – two recent studies from the Quaggin lab, NU
Susan Quaggin (NU) was a co-organizer and a speaker at the CBC Exploratory Workshop (2014).
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January 30, 2018
SUCCESS STORY
Visualizing exposed potassium channels to evaluate myelin damage in multiple sclerosis—a novel PET tracer technique developed by UChicago team with ties to CBC
Chin-Tu Chen (UChicago) received a CBC Postdoctoral Research Award (2015).
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January 30, 2018
SUCCESS STORY
“The meat in the sandwich”—scale-like calcite matrices that could help affix biological tissues to medical implants developed by a UChicago team led by a CBC awardee, Bozhi Tian.
Bozhi Tian, UChicago, and a postdoc in his lab, Yucai Wang, received a CBC Postdoctoral Research Award (2014).
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January 30, 2018
SUCCESS STORY
Native nano-vesicles and synthetic nano-particles: both can trigger an immune response that significantly reduces cancer metastasis—reports a NU team led by a CBC awardee, Shad Thaxton
Shad Thaxton, NU, and a postdoc in his lab, Linda Foit, received a CBC Postdoctoral Research Award (2014).
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January 25, 2018
SUCCESS STORY
Past CBC awardees, Chad Mirkin and Vinayak David, NU, develop a “mind-bending” technology to build “light-bending” materials from DNA and gold nanoparticles
Chad Mirkin, NU, was a co-recipient of a CBC Lever Award (2010), whereas Vinayak David, NU was a co-recipient of a CBC Spark Award (2009).
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January 25, 2018
SUCCESS STORY
Learning from a predator… about learning. Two CBC awardees, Stephanie Palmer and Jason MacLean, UChicago, dissect the process of visual prediction in a hungry salamander
Stephanie Palmer and Jason MacLean, are co-recipients of a CBC Catalyst Award (2015). Palmer also serves on the CBC Catalyst Review Board (CRB; 2017-present)
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January 24, 2018
SUCCESS STORY
A past CBC symposium speaker, Peter Penzes, NU, named director of the newly launched Center for Autism and Neurodevelopment
Peter Penzes, NU, was an invited speaker at the 14th Annual CBC Symposium (2016).
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January 24, 2018
SUCCESS STORY
A past CBC awardee Chad Mirkin, NU, to add prestigious 2018 Remsen Memorial Lecture Award to the fast growing list of his accolades
Chad Mirkin, NU, is a co-recipient of a CBC Lever Award (2010).
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January 18, 2018
SUCCESS STORY
ClostraBio, a startup co-founded by UChicago scientists with ties to CBC, called a “promising, emerging venture”
Cathy Nagler, UChicago, has benefited from the first CBC Lever Award (2008) to the Chicago Center for Systems Biology (CCSB) via the CCSB/CBC Fellowship, awarded to Aly Azeem Khan—a postdoctoral fellow in her lab. Jeffrey Hubbell, UChciago, received a CBC HTS Award (2016).
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January 11, 2018
SUCCESS STORY
“Tag, You‘re It!” Tagging proteins with ubiquitin by different E3 ligases may be key to specificity of the ubiquitin-dependent protein degradation
Hiroaki Kiyokawa, NU and Jun Yin, currently at Georgia State University but formerly at UChicago, are recipients of a CBC Catalyst Award (2011). Kiyokawa and his postdoc, Xianpeng Liu, received a CBC Postdoctoral Research Award (2014).
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January 11, 2018
SUCCESS STORY
“Mind-plus-machine partnership” — a past CBC Scholar, Adam Pah, NU, encourages keeping up with the progress in machine learning and artificial intelligence
Adam Pah (NU) was a CBC Scholar, Class of 2011.
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January 11, 2018
SUCCESS STORY
How gut bacteria can help in fighting cancer—a CBC awardee, Thomas Gajewski, UChicago, explains
Thomas Gajewski (UChicago) is a recipient of a CBC Catalyst Award (2013) and a CBC Postdoctoral Research Award (2014).
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January 10, 2018
NEWS
“Lunch & Learn” at the University of Illinois at Chicago
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January 4, 2018
SUCCESS STORY
CBC Awardee, Dr. Louis Philipson, UChicago, named first James C. Tyree Professor in Diabetes Research and Care
Louis Philipson (UChicago), received a CBC Spark Award (2011).
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January 4, 2018
SUCCESS STORY
CBC awardee, Elizabeth McNally, NU and her collaborators, induce muscle regeneration in mouse model using human stem cells
Elizabeth McNally (NU; at UChicago at the time of the awards), received a CBC Spark and a CBC Catalyst (2009).
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January 4, 2018
SUCCESS STORY
New molecule with promise to combat multiple myeloma discovered in NU center established with CBC support
Gary Schiltz and Rama Mishra, (NU), co-authors on a paper attributed to CBC funding via a Lever Award (2009).
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January 3, 2018
“in the news”
CBC recognized among important local resources for entrepreneurs as Chicago becomes a hub for biomedical innovation
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January 3, 2018
SUCCESS STORY
Past CBC symposium speaker, Mark Ratain, UChicago, comments on the new Personalized Therapeutics Clinic at UChicago
Mark Ratain (UChicago) was an invited speaker at the 5th Annual CBC Symposium (2007)
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January 3, 2018
SUCCESS STORY
CBC community member Laimonis (Lou) Laimins, NU, named Fellow of the American Association for the Advancement of Science (AAAS)
Lou Laimins (NU) was a 13th Annual CBC Symposium (2015) co-organizer.
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January 3, 2018
SUCCESS STORY
CBC affiliate Teresa Woodroof among three NU scientists named to National Academy of Inventors
Teresa Woodruff (NU) was closely affiliated with the CBC Spark (2009) team of Thomas O’Halloran and Vinayak Dravid (NU) and Jonathan Silverstein (UChicago).
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January 2, 2018
SUCCESS STORY
Improving immunotherapy—impact of UChicago scientists, including three CBC community members: Thomas Gajewski, Melody Swartz and Everett Vokes
Thomas Gajewski (UChicago) is a recipient of a CBC Catalyst Award (2013) and a CBC Postdoctoral Research Award (2014). Melody Swartz (UChicago) was an invited speaker at the 9th Annual CBC Symposium (2011) and Everett Vokes was a panelist at the Celebration of the CBC Funding Renewal (Dec. 16, 2016).
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