The mission of the Chicago Biomedical Consortium (CBC) is to stimulate collaboration among scientists at Northwestern University, The University of Chicago, the University of Illinois at Chicago and others to accelerate discovery that will transform biomedical research and improve the health of humankind.
The CBC gratefully acknowledges support from the Searle Funds at The Chicago Community Trust.

February 26, 2018
CBC is inviting new applications for the Accelerator Award program

Accelerator Award is a milestone-driven award program ($100,000 for 1st year) focused on translational research toward therapeutics or associated biomarkers and diagnostics.

Fall 2018 round Letter of Intent (LOI) submissions open at 8:00 AM on June 4, 2018 and close at 5:00 PM on June 8, 2018.

If you plan to apply, please make sure that you are conforming to the MOST RECENT RFA. Applications not conforming to the specified guidelines will NOT be accepted. In addition, applicants, if selected, MUST be available to present their projects at a CBCAN meeting on August 2 and/or August 16, 2018. Both meetings will be held on a Thursday, from 4:00-7:00 PM, at Prentice Women Hospital Conference Center downtown Chicago. MARK YOUR CALENDARS!

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▸ RFA (Please make sure that you are conforming to the MOST RECENT RFA.)

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CBC on Twitter

March 23, 2018
TTC-352, a new breast cancer agent developed by Debra Tonetti and Greg Thatcher, UIC, may become a therapeutic for patients with estrogen receptor-positive breast cancer that expresses specific biomarkers

Congratulations to UIC researchers Debra Tonetti and Greg Thatcher! Their new anti-cancer agent, called TTC-352, has entered the Phase I of clinical trials as a potential future therapeutic for patients with a hormone therapy-resistant breast cancer. CBC is very proud to share that both, Tonetti and Thatcher are long time CBC affiliates. They both actively participated in CBC educational events including the CBC Annual Symposia, CBC Tech Day and CBC Science Day. Each is also a multiple CBC awardee: Tonetti received a CBC Catalyst Award (2009) and a CBC HTS Award (2015), the latter together with Thatcher, who was also granted a second CBC HTS Award the same year. Finally, both, Tonetti and Thatcher have served on CBC Catalyst Review and CBC Accelerator Review Boards, respectively. The CBC is grateful for their service and wishes them continuous success on the path to therapeutics!

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March 23, 2018
UIC research team with links to CBC awarded $2.7 million NIH grant to study the lung microbiome, immune system, and their roles in the lung inflammatory disease, sarcoidosis

Congratulations to the UIC team recently awarded a $2.7 million grant from the NIH to support research on the causes of sarcoidosis – a devastating lung disease, prevalent among the African American population. Specifically, the research will examine the interactions between the lung microbiome and the immune system in healthy and sick individuals. The goal is to identify the differences in the microbiome composition and in the related immune responses among the examined patients. These sarcoidosis biomarkers would support the design of more effective and individualized treatment protocols. The members on the NIH grant include Patricia Finn, David Perkins, Nadera Sweiss and Yang Dai, a co-recipient of a CBC Catalyst Award (2009) for her research on the role of estrogen receptors in carcinogenesis.

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March 23, 2018
Can a phone ‘read’ your mood? BiAffect app developers, Dr. Alex Leow and a past CBC awardee, Peter Nelson, UIC, explain.

A UIC team of Dr. Alex Leow and Peter Nelson that participated in the development of a new app, called Biaffect, is optimistic that the app may help in the study and, perhaps in the future, the management of mood disorders such as bipolar disorder. The app, now available for free in the App store, analyses the user’s writing with a goal of identifying ‘virtual biomarkers.’ Such writing patterns can be correlated with mood swings, and in extreme cases such as manic and depressive episodes, detect bipolar disorder. The team hopes that future versions of the app, sensitized and improved by users’ big-data analysis, may learn to predict upcoming episodes and thus help mood disorder sufferers better cope with the disease. CBC is proud to have supported Nelson’s research in the past with a CBC Catalyst Award (2006). Congratulations to all researchers involved in the development of this promising approach!

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March 13, 2018
Director’s Corner
Connecting with my past and celebrating the chemistry of the future at the Lilly Grantee Symposium

Yesterday I had the pleasure of attending the 18th Biennial Lilly Grantee Symposium in Chemistry. (…) The Grantee program is the oldest of its type across pharma, although there are now a number of prestigious pharma chemistry awards that parallel the original Lilly Grantee program. Started in 1965, the award recognizes, celebrates and supports academic chemists early in their career, prior to gaining tenure, and provides them with a 2-year unrestricted grant to enable them to better take the scientific risks necessary to advance the field and establish themselves across the community. The Symposium brings together the most recent grantees, along with a distinguished alumnus of the program for a day to celebrate chemistry writ large.
Jim Audia

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Featured Events

April 11, 2018
UChicago Department of Neurobiology
The 2018 Carlson Symposium on Neuroscience: Motor Circuits in Health and Disease

April 25-26, 2018
UChicago Computation Institute
GlobusWorld 2018: Connecting your Research Universe

May 10, 2018
NU Cognitive Neurology and Alzheimer’s Disease Center
24th Annual Alzheimer Day

May 16, 2018
UChicago Computation Institute
Future Compute: A Celebration of the Computation Institute

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Biotech & Entrepreneurship

March 22, 2018
Women in Bio (WiB) – Chicago Chapter
Diversity & Inclusion in Health and Life Sciences: Where are we today?

Research supporting the business case for diversity in the workplace continues to grow. Yet, it is widely accepted that diversity is lacking in the health and life science sectors. Indeed, recent studies highlight that the gender gap in boardrooms and C-suites is among the highest in the health and life sciences as compared to other industries. Join our panel of executive women to explore why these gaps exist and what we and our organizations can do to make a change.
▸ More info and registration details

June 13-14, 2018
SBIR/STTR Grant Writing Workshop

PROPEL is hosting this 2-day Intensive Workshop, provided by BBC Entrepreneurial Training & Consulting (BBCetc), that will cover all aspects of writing SBIR/STTR grants focused on life science technologies including: eligibility, sources of funding and agency differences, understanding what reviewers look for, step-by-step instruction on how to write each section of your proposal.

Registration opens April 1. For questions, contact

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