Homepage Archives 2013

Homepage Archives contain CBC announcements and news, success stories’ snippets and Chicago Biotech news, that have been chronologically posted on the CBC homepage throughout the year.


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2013

December 18, 2013
ANNOUNCEMENT
CBC Postdoctoral Research Grant Program: RFA revised 12/18/13
The CBC is pleased to announce the initiation of a new program, the CBC Postdoctoral Research Grant Program. This program is designed to fund innovative research conducted by postdoctoral fellows under the supervision of their faculty advisor/mentor in core research facilities at the CBC universities. The program will accept applications twice a year. Spring 2014 submissions deadline: 5PM on January 31, 2014. (CBC Postdoctoral Research Grant Description and RFA)


December 2, 2013
ANNOUNCEMENT
LOOP CONNECTIONS: Modifications of RNA and DNA in health and disease
The 2013 Fall CBC Scholars “Loop Connections” seminar took place on September 26, 2013 at the University of Chicago. The seminar featured Dr. Chuan He, Department of Chemistry, UChicago and Dr. Jindan Yu, Department of Medicine, NU.  Over 110 students, faculty and staff from the three CBC universities attended the event. (more info)


November 25, 2013
SUCCESS STORY
Life on Earth Began in a World Based Solely on RNA
In 2009, a Spark team consisting of Jonathan Staley (UChicago), Erik Sontheimer (NU) and Alexander Mankin (UIC) received a Spark Award to fund research investigating "Noncoding RNA Structure, Function, and Evolution." Over the years, this team has been extremely productive generating multiple publications and external funding. On November 6, 2013, Dr. Staley, along with Dr. Joseph Piccirilli, a co-investigator of the Spark team, were senior authors on a research report published in Nature, “RNA catalyses nuclear pre-mRNA splicing,” which is a continuation of the work originally funded by the 2009 Spark Award. This discovery establishes that RNA, not protein, mediates catalysis within the spliceosome. (more info)


November 6, 2013
CBC NEWSLETTER, VOL. 10
Announcing NEW Award Program and Ongoing Funding Opportunities
The CBC is pleased to announce the initiation of a new program, the CBC Postdoctoral Research Grant Program. CBC invites new applications in the new program and in several other ongoing award programs. ▸ Read more


November 5, 2013
ANNOUNCEMENT
CBC Announces a New Award Program: CBC Postdoctoral Research Grant Program
The CBC is pleased to announce the initiation of a new program, the CBC Postdoctoral Research Grant Program. This program is designed to fund innovative research conducted by postdoctoral fellows under the supervision of their faculty advisor/mentor in core research facilities at the CBC universities. The program will accept applications twice a year. Spring 2014 submissions will open January 20, 2014 and close at 5PM on January 31, 2014. (CBC Postdoctoral Research Grant Description and RFA)


November 4, 2013
SUCCESS STORY
A Genetic Map For Complex Diseases
In 2012, Andrey Rzhetsky’s team received a CBC Lever Award to help fund the Conte Center for Computational Neuropsychiatric Genomics. A year later, on September 26, 2013, the team reported in Cell the development of a "genetic map" of associations between Mendelian disease loci and co-occurrence of "complex diseases" such as autism, schizophrenia, diabetes and heart disease. The "map" promises to become useful in genetic and clinical evaluations of the risk of developing complex diseases and in understanding therapeutic efforts to cope with such illnesses. (more info)


November 1, 2013
ANNOUNCEMENT
CBC HTS Supplemental Grant Program: Applications are now being accepted
The CBC invites CBC university affiliates of any rank to submit applications to the CBC HTS Supplemental Grant Program. Applications deadline: 5PM on November 22, 2013. Please note that the RFA has been revised. Applicants must follow the eligibility requirements and application instructions that are included in the revised RFA. (HTS Supplemental Grant Program Description and RFA)


October 31, 2013
ANNOUNCEMENT
CSAP Pilot Projects: New Application Round Announced
The CBC invites new applications for the Chicago Synthetic Antibody Pipeline (CSAP) Pilot Projects. Pilot Projects are expected to focus on developing ways to extend the applications of the sAB technology. Application deadline: January 1, 2014. (CSAP Pilot Projects RFA)


October 30, 2013
NEWS
CBC Announces 2013 Spring Round Catalyst Awards
» Stephen J. Kron, MD, PhD (UChicago) and Preston T. Snee, PhD (UIC) for project: Radiation-guided delivery of quantum dot theranostic nanoparticles
» Andrei Karginov, PhD (UIC) and Michael Glotzer, PhD (UChicago) for project: An “And-Gate” for Optogenetic Control Of Protein Kinases
» Michael Jewett, PhD (NU) and Jared Lewis, PhD (UChicago) for project: Engineering Prokaryotic Translation for Artificial Metalloenzyme Production
» Robert Daum, MD (UChicago) and Michael E. Johnson, PhD (UIC) for project: A Novel Antimicrobial Strategy Against Methicillin-Resistant S Aureus (MRSA)
» Jie Liang, PhD and Amy Kenter, PhD (UIC) and John Marko, PhD (NU) for project: Characterizing in Vivo Chromatin Folding Landscape of IgH locus on Chromosome 12
» Thomas Gajewski, MD, PhD and Haochu Huang, PhD (UChicago) and Xiaozhong Wang, PhD (NU) for project: Identifying Immune Evasion Mechanisms in Tumors Via a Genome-Wide shRNA Screen


August 19, 2013 (updated October 23, 2013)
REPORT
CBC HTS Award Workshops
The CBC hosted 3 HTS Award workshops in August of 2013. Close to thirty researchers came to the workshops to learn about the CBC HTS Award program, the three HTS Facilities associated with the CBC universities, and exciting ongoing screens. As the new HTS Award application round opens Novemebr 1, 2013, up-to-date information highlighting the HTS facilities and a brief overview of HTS has been posted to assist you in determining if HTS is a viable resource to use in your research and to determine which HTS facility best meets your needs. (read more)


October 7, 2013
ANNOUNCEMENT
Fall Round of HTS Award Application is Opening Soon
The CBC invites CBC university affiliates of any rank to submit applications to the CBC HTS Supplemental Grant Program. Applications open on November 1, 2013 and close at 5PM on November 22, 2013. Please note that the RFA has been revised. Applicants must follow the eligibility requirements and application instructions that are included in the revised RFA. (HTS Supplemental Grant Program Description and RFA)


October 7, 2013
ANNOUNCEMENT
Exploratory Workshops: Applications now being accepted
CBC invites faculty members to apply for the Exploratory Workshops Program. Application deadline: 5pm, Friday, December 6, 2013. (CBC Exploratory Workshops Program Description and RFA)


September 23, 2013
ANNOUNCEMENT
CBC 11th Annual Symposium
The 11th Annual CBC Symposium, Exploring Human Biology with Small Molecules, will be held at the University of Chicago Campus, on Friday, October 11, 2013. For program details click here.


September 18, 2013
SUCCESS STORY
Signal Transduction Factors in Breast Cancer
Brian Shy, an MD/PhD student in the Department of Biochemistry and Molecular Genetics at the UIC, was selected as a CBC Scholar in 2013. Results of Brian’s work on the role of signal transduction factors in breast cancer were recently published and featured on the journal cover in the July 11, 2013 issue of Cell Reports, “Regulation of Tcf7l1 DNA Binding and Protein Stability as Principal Mechanisms of Wnt/β-Catenin Signaling.” (more info)


September 3, 2013
ANNOUNCEMENT
CBC Scholars "Loop Connections" Seminar at UChicago
This CBC Scholars-organized "Loop Connections" Seminar will feature Chuan He (UChicago) and Jindan Yu (NU) and will be held at UChicago Campus on Thursday, September 26, 2013 at 4:00 pm. (more info)


September 3, 2013
ANNOUNCEMENT
Chicago Synthetic Antibody Pipeline open for business
Supported by a CBC Lever Award, the Chicago Synthetic Antibody Pipeline (CSAP) is now open to the CBC community. CSAP is a high throughput pipeline designed to produce the next generation of affinity reagents: customized synthetic antibodies (sABs). CBC researchers can nominate protein antigens as targets for sAB generation using existing technology and/or apply for Pilot Projects that will focus on developing ways to extend the applications of the sAB technology. (more info)


August 28, 2013
ANNOUNCEMENT
Registration for the CBC 11th Annual Symposium is closing soon
The 11th Annual CBC Symposium, Exploring Human Biology with Small Molecules, will be held at the University of Chicago Campus, on Friday, October 11, 2013. For program details and to register click here.


August 19, 2013
REPORT
CBC HTS Award Workshops
The CBC hosted 3 HTS Award workshops in August of 2013. Close to thirty researchers came to the workshops to learn about the CBC HTS Award program, the three HTS Facilities associated with the CBC universities, and exciting ongoing screens. The CBC Staff and HTS Facility Directors were on-site for Q&As. (read more)


August 19, 2013
ANNOUNCEMENT
SBIR/STTR Grant Writing Workshop
PROPEL’s SBIR/STTR grant writing workshop is September 16-17, 2013, downtown Chicago. This two-day ntensive workshop will combine all aspects of writing SBIR/STTR grants focused on life science technologies including: eligibility, sources of funding and agency differences, understanding what reviewers look for, step-by-step instruction on how to write each section of your proposal. The workshop will cover all agencies, including DOD, NSF and NIH, with detailed emphasis on NIH. For details and to register click here.


August 19, 2013
ANNOUNCEMENT
Catalyst Award Program: Applications now being accepted
The CBC’s Catalyst Award program offers funding of up to $200K for one- or two-year new inter-institutional collaborative research projects. Fall 2013 Round online submission is now open. Proposal submission deadline is 5pm, Wednesday, August 28, 2013. (Catalyst RFA)


August 9, 2013
SUCCESS STORY
Nanofabrication at your fingertips
Supported by a CBC Lever Award, Chad Mirkin’s group at NU reported July 19, 2013, in Nature Communications the development of a breakthrough lithographic tool that is capable of creating varied and complex patterns at nano-resolution on a centimeter-scale surface. This nanofabrication tool is low-cost and similar to a desktop printer. This "desktop nanofab" could enable the production of nanoscale working devices and structures at the point of use in both academia and industry. (read more)


August 8, 2013
REPORT
2013 CBC Summer Workshop in Proteomics and Informatics
The CBC Summer Workshop in Proteomics and Informatics kicked off its sixth year on July 22-26, 2013. The popular hands-on workshop took place at the CBC/UIC Mass Spectrometry Metabolomics and Proteomics Facility (MMPF) on UIC’s West Campus. Twenty-one participants from the three CBC universities and also researchers from Loyola, Rush, and J.R. Simplot Plant Sciences (Boise, ID) attended the intense weeklong workshop. (read more)


August 5, 2013
ANNOUNCEMENT
CBC Exploratory Workshops: Applications now being accepted
CBC invites faculty members to apply for the Exploratory Workshops Program. Application deadline: 5pm, Friday, October 4, 2013. (CBC Exploratory Workshops Program Description and RFA)


July 16, 2013
CBC NEWSLETTER, VOL. 9
CBC funding opportunities and upcoming citywide events in the biomedical sciences
Welcome! Learn about current CBC funding opportunities and upcoming citywide events in the biomedical sciences. ▸ Read more


July 16, 2013
ANNOUNCEMENT
3 HTS Workshops
Come and learn about the CBC High Throughput Screening (HTS) Award program, the HTS Facilities at the three CBC universities, and exciting ongoing screens. The CBC Staff and HTS Facility Directors will be on-site for Q&As. Three workshps will be offered:
@ UIC: August 12
@ NU Chicago: August 14
@ UChicago: August 16


July 16, 2013
ANNOUNCEMENT
CBC Invites New Catalyst Award Applications
The CBC’s Catalyst Award program offers funding of up to $200K for one- or two-year new inter-institutional collaborative research projects. Fall 2013 Round online submission opens August 19, 2013. Proposal submission deadline is 5pm, Wednesday, August 28, 2013. (Catalyst RFA)


July 16, 2013
ANNOUNCEMENT
Registration now open for the CBC 11th Annual Symposium
The 11th Annual CBC Symposium, Exploring Human Biology with Small Molecules, will be held at the University of Chicago Campus, on Friday, October 11, 2013. For program details and to register click here.


June 28, 2013
NEWS
CBC Announces 2013 Spring Round HTS Awards
The CBC is pleased to announce that eleven HTS Awards were made in 2013 Spring application round. The awarded projects will be conducted in the HTS facilities located at the three CBC universities. (read more)


June 26, 2013
ANNOUNCEMENT
Chicago Synthetic Antibody Pipeline open for business
CBC is pleased to announce that, with the support of a CBC Lever Award, the Chicago Synthetic Antibody Pipeline (CSAP) is now open to the CBC community. CSAP is a high throughput pipeline designed to produce the next generation of affinity reagents: customized synthetic antibodies (sABs). CBC researchers can nominate protein antigens as targets for sAB generation using existing technology and/or apply for Pilot Projects that will focus on developing ways to extend the applications of the sAB technology. Application deadline: September 2, 2013. (more info)


June 18, 2013
ANNOUNCEMENT
LOOP CONNECTIONS: The Science of Molecular Coercion
The engineering of biological systems was the focus of the spring quarter’s “Loop Connections” Seminar Series, organized by the CBC Scholars on May 29th at Northwestern University. The seminar featured the work of two bioengineers, Northwestern University’s Michael Jewett and University of Chicago’s Jared Lewis. (read more)


June 12, 2013
SUCCESS STORY
Many tissues, one body: Intertissue collaboration in stress
Supported by a CBC Lever Award, Rick Morimoto’s team at NU reported June 6, 2013, in Cell, that, in C. elegans, one damaged tissue not only attempts to self-repair but also reds other tissues and organs within the body about the ongoing stress. In consequence, the non-harmed but alarmed healthy tissues respond by releasing factors that help to mend the damaged one. This transcellular, intertissue stress detection and signaling mechanism is thought to increase the organism’s chances of survival. (read more)


June 8, 2013
ANNOUNCEMENT
CBC Exploratory Workshops: Applications now being accepted
CBC invites faculty members to apply for the Exploratory Workshops Program. Application deadline: 5pm, Friday, August 2, 2013 . (CBC Exploratory Workshops Program Description and RFA)


June 7, 2013
NEWS
CBC Scientific Director Rick Morimoto Awarded Order of Academic Palms
On June 6, 2013, Richard I. Morimoto, the Bill and Gayle Cook Professor of Biology in the Department of Molecular Biosciences at Northwestern University, has received the Commandeur de l’Ordre des Palmes Académiques, which is the Commander grade of the French Republic’s Order of Academic Palms. Rick is one of the founders of the CBC and a CBC Scientific Director. Congratulations! (read more)


May 28, 2013
ANNOUNCEMENT
CBC Exploratory Workshops: Applications now being accepted
CBC invites faculty members to apply for the Exploratory Workshops Program. The program provides support for small workshops to encourage collaborative interactions across the CBC institutions. These workshops are intended to stimulate new Catalyst Award submissions, Program Project Grants from the NIH, and eventually Lever Awards associated with large, multi-investigator NIH grants. Application deadline: 5pm, Friday, June 7, 2013. (CBC Exploratory Workshops RFA)


May 28, 2013
REPORT
Lipoproteins take stage at the 4th CBC Exploratory Workshop
Eleven researchers from the three CBC institutions convened on May 15, 2013 at the University of Illinois at Chicago for the fourth CBC Exploratory Workshop titled “Lipoproteins.” The workshop centered on sharing exciting findings and interests, discussing complementary approaches used the participating laboratories and on fostering future collaborations to study lipoproteins. (read more)


February 15, 2013 (updated May 7, 2013)
ANNOUNCEMENT
CBC Announces 2012 Fall Round Catalyst Awards
» Q. Tian Wang, PhD (UIC) and Hans-Georg Simon, PhD (NU) for project: Proteomic Characterization of Epicardial-Myocardial Signaling and Regenerative Activity
» Bruce Lahn, PhD (UChicago) and John Crispino, PhD (NU) for project: Dissecting cis versus trans regulation of gene expression using in vitro transcription
» Primal de Lanerolle, PhD (UIC) and Steven T. Kosak, PhD (NU) for project: Nuclear Actin and Genome Organization


May 2, 2013
ANNOUNCEMENT
CBC Scholars "Loop Connections" Seminar at NU
This CBC Scholars-organized "Loop Connections" Seminar will feature Michael Jewett, PhD (NU) and Jared Lewis, PhD (UChicago) and will be held at NU Evanston Campus on Wednesday, May 29, 2013 at 3:30pm. (more info)


April 30, 2013
REPORT
CBC Scholars share their research at the Fourth Annual Scientific Exchange
On April 17, 2013, CBC Scholars assembled at the Gleacher Center in downtown Chicago for the Fourth Annual CBC Scholars Scientific Exchange. There, the Scholars presented ‘snapshots’ of their dissertation projects, generating a pastiche of amazing Chicago biological research. (read more)


April 19, 2013
ANNOUNCEMENT
The CBC Summer Workshop in Proteomics and Informatics
CBC invites students, staff, and faculty to participate in our 6th annual hands-on Summer Workshop in Proteomics and Informatics at the CBC/UIC Mass spectrometry Metabolomics and Proteomics Facility. This intensive workshop will offer a theoretical and practical introduction to tandem mass spectrometry proteomics, including the key experimental methods and computational tools needed to pursue analysis of complex proteomic samples. Registration begins April 22, 2013. Attendees will be selected on June 17th. Limited seats available. Please see workshop webpage for full details of the registration process.


April 12, 2013
NEWS
CBC Junior Investigator Wins Major Cancer Research Award
Sadie Wignall, PhD, CBC Junior Investigator and Assistant Professor of Molecular Biosciences in the Weinberg College of Arts and Sciences at Northwestern University, won a prestigious Damon Runyon-Rachleff Innovation Award. (read more)


April 5, 2013
“IN THE NEWS”
A boost for biotech startups
The recent Chicago Sun-Times article, “A boost for biotech startups”, discusses how the uniquely collaborative research environment, pioneered by the CBC and fostered by the Chicago Innovation Mentors, is beginning to impact the Chicago-area biotech scene. (read more)


April 2, 2013
REPORT
CBC Scholars volunteer again at the CPS Science Fair
Nine CBC Scholars volunteered this year as judges at the 63rd annual Chicago Public Schools (CPS) Science Fair held at the Museum of Science and Industry in Hyde Park, Chicago, on March 22, 2013. (read more)


March 15, 2013
ANNOUNCEMENT
CBC Exploratory Workshops: Applications now being accepted
CBC invites faculty members to apply for the Exploratory Workshops Program. The program provides support for small workshops to encourage collaborative interactions across the CBC institutions. These workshops are intended to stimulate new Catalyst Award submissions, Program Project Grants from the NIH, and eventually Lever Awards associated with large, multi-investigator NIH grants. Application deadline: 5pm, Friday, April 19, 2013. (CBC Exploratory Workshops RFA)


March 4, 2013
ANNOUNCEMENT
Position Open: Associate Director, CBC
All applications received before March 29, 2013 will be considered. (more info)


February 27, 2013
ANNOUNCEMENT
CBC Announces a New Program: High Throughput Screening (HTS) Award
CBC is launching a new, 1:1 HTS Matching Grant Program (up to $20,000) to help fund innovative small molecule discovery. The intent of this program is to support pilot projects involving biomedically-relevant targets using a HTS facility located at one of the CBC universities. Spring deadline: 5 pm, Monday, April 22, 2013. (HTS Award RFA)


February 25, 2013
ANNOUNCEMENT
CBC Invites New Catalyst Award Applications – Online Submission is Now Open
The CBC’s Catalyst Award program offers funding of up to $200K for one- or two-year new inter-institutional collaborative research projects. Spring 2013 Round online submission is now open. Proposal submission deadline is 5pm, Wednesday, March 6, 2013. (Catalyst RFA)


February 15, 2013
NEWS
CBC Announces 2012 Fall Round Catalyst Awards
» Q. Tian Wang, PhD (UIC) and Hans-Georg Simon, PhD (NU) for project: Proteomic Characterization of Epicardial-Myocardial Signaling and Regenerative Activity
» Bruce Lahn, PhD (UChicago) and John Crispino, PhD (NU) for project: Dissecting cis versus trans regulation of gene expression using in vitro transcription
» Primal de Lanerolle, PhD (UIC) and Steven T. Kosak, PhD (NU) for project: Nuclear Actin and Genome Organization (pending administrative approval)


February 6, 2013
ANNOUNCEMENT
Workshop on the CBC Catalyst Award Program
The CBC invites faculty members at UIC, Northwestern, and UChicago to attend a Workshop on the CBC Catalyst Award program to be held on Wednesday, February 13, 2013, at the UIC campus. This workshop aims to demystify the Catalyst program and help the CBC community members prepare strong proposals for the next deadline (March 6, 2013) and beyond. (more info)


February 5, 2013
REPORT
The CBC Exploratory Workshop on Cellular Heterogeneity
The third CBC Exploratory Workshop, titled “Cellular Heterogeneity” took place on Wednesday, January 30, 2013 at the University of Chicago Gleacher Center downtown Chicago. The workshop gathered 13 scientists from the three CBC institutions. Marsha Rosner (UChicago) and Neil Kelleher (NU) co-organized this full-day event. (read more)


February 2, 2013
ANNOUNCEMENT
Save the date: 11th Annual CBC Symposium
The 11th Annual CBC Symposium, Exploring Human Biology with Small Molecules, will be held at the University of Chicago Campus, on Friday, October 11, 2013. (more info)


January 29, 2013
ANNOUNCEMENT
Position Open: Associate Director, CBC
All applications received before March 15, 2013 will be considered. (more info)


January 25, 2013
REPORT
The CBC Ovarian Cancer Workshop
The CBC Ovarian Cancer Workshop, supported by the recently-launched CBC Exploratory Workshop Program, took place at the University of Illinois at Chicago (UIC) College of Pharmacy on January 12, 2013. The goal of the day-long workshop was to initiate the development of a Chicago-based ovarian cancer consortium that would attempt to identify the most pressing scientific questions in both ovarian cancer biology and treatment. (read more)


January 8, 2013
NEWS
Join us in welcoming the Class of 2013 CBC Scholars
Nine new CBC Scholars were welcomed to the CBC at a luncheon on January 7, 2013 at Bistrot Margot in Chicago’s Old Town neighborhood.  The CBC Scholars Program is in its fourth year of operation and aims to develop a leadership forum for students from the three CBC universities to advance the CBC mission of fostering collaboration and excellence. (read more)