CBC-Funded Publications 2018

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2018

Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, Ivanov AR, Jensen ON, Jewett MC, Kelleher NL, Kiessling LL, Krogan NJ, Larsen MR, Loo JA, Ogorzalek Loo RR, Lundberg E, MacCoss MJ, Mallick P, Mootha VK, Mrksich M, Muir TW, Patrie SM, Pesavento JJ, Pitteri SJ, Rodriguez H, Saghatelian A, Sandoval W, Schlüter H, Sechi S, Slavoff SA, Smith LM, Snyder MP, Thomas PM, Uhlén M, Van Eyk JE, Vidal M, Walt DR, White FM, Williams ER, Wohlschlager T, Wysocki VH, Yates NA, Young NL, Zhang B. How many human proteoforms are there? Nat Chem Biol. 2018 Feb 14;14(3):206-214. (PubMed)

Allen SD, Bobbala S, Karabin N, Modak M, Scott EA. Benchmarking bicontinuous nanospheres against polymersomes for in vivo biodistribution and dual intracellular delivery of lipophilic and water soluble payloads. ACS Appl Mater Interfaces. 2018 Oct 10;10(40):33857-33866. (PubMed)

Allen SD, Liu YG, Bobbala S, Cai L, Hecker PI, Temel R, Scott EA. Polymersomes scalably fabricated via flash nanoprecipitation are non-toxic in non-human primates and associate with leukocytes in the spleen and kidney following intravenous administration. Nano Research. 2018 11: 5689. (Springer)

Alvares K, DeHart CJ, Thomas PM, Kelleher NL, Veis A. The unique biomineralization transcriptome and proteome of Lytechinus variegatus teeth. Connect Tissue Res. 2018 Dec;59(sup1):20-29. (PubMed)

Alzrigat M, Jernberg-Wiklund H, Licht JD. Targeting EZH2 in Multiple Myeloma-Multifaceted Anti-Tumor Activity. Epigenomes. 2018 Sep;2(3). (PubMed)

Bailey LJ, Sheehy KM, Dominik PK, Liang WG, Rui H, Clark M, Jaskolowski M, Kim Y, Deneka D, Tang WJ, Kossiakoff AA. Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination. J Mol Biol. 2018 Feb 2;430(3):337-347. (PubMed)

Barbeira AN, Dickinson SP, Bonazzola R, Zheng J, Wheeler HE, Torres JM, Torstenson ES, Shah KP, Garcia T, Edwards TL, Stahl EA, Huckins LM; GTEx Consortium, Nicolae DL, Cox NJ, Im HK. Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. Nat Commun. 2018 May 8;9(1):1825. (PubMed)

Beaubier N, Tell R, Huether R, Bontrager M, Bush S, Parsons J, Shah K, Baker T, Selkov G, Taxter T, Thomas A, Bettis S, Khan A, Lau D, Lee C, Barber M, Cieslik M, Frankenberger C, Franzen A, Weiner A, Palmer G, Lonigro R, Robinson D, Wu YM, Cao X, Lefkofsky E, Chinnaiyan A, White KP. Clinical validation of the Tempus xO assay. Oncotarget. 2018 May 25;9(40):25826-25832. eCollection 2018 May 25. (PubMed)

Bennett RL, Licht JD. Targeting Epigenetics in Cancer. Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:187-207. (PubMed)

Bhuripanyo K, Yiyang Wang Y, Liu X, Zhou L, Liu R, Duong D, Zhao B, Bi Y, Zhou H, Chen G, Seyfried NT, Chazin WJ, Kiyokawa H, Yin J. Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer. Sci Adv. 2018 Jan 3;4(1):e1701393. (PubMed)

Biancucci M, Minasov G, Banerjee A, Herrera A, Woida PJ, Kieffer MB, Bindu L, Abreu-Blanco M, Anderson WF, Gaponenko V, Stephen AG, Holderfield M, Satchell KJF. The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling. Sci Signal. 2018 Oct 2;11(550). (PubMed)

Bobbala S, Allen SD, Scott EA. Flash nanoprecipitation permits versatile assembly and loading of polymeric bicontinuous cubic nanospheres. Nanoscale. 2018 Mar 15;10(11):5078-5088. (PubMed)

Brahmachari S, Dittmore A, Takagi Y, Neuman KC, Marko JF. Defect-facilitated buckling in supercoiled double-helix DNA. Phys Rev E. 2018 Feb;97(2-1):022416. (PubMed)

Briscoe SD, Albertin CB, Rowell JJ, Ragsdale CW. Neocortical Association Cell Types in the Forebrain of Birds and Alligators. Curr Biol. 2018 Mar 5;28(5):686-696.e6. (PubMed)

Bryois J, Garrett ME, Song L, Safi A, Giusti-Rodriguez P, Johnson GD, Shieh AW, Buil A, Fullard JF, Roussos P, Sklar P, Akbarian S, Haroutunian V, Stockmeier CA, Wray GA, White KP, Liu C, Reddy TE, Ashley-Koch A, Sullivan PF, Crawford GE. Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia. Nat Commun. 2018 Aug 7;9(1):3121. (PubMed)

Bugga P, Mrksich M. Dynamic Substrates for Cell Biology. Curr Opin Colloid Interface Sci. 2018 Nov;38:80-87. (PubMed)

Busque L, Godley LA. MBD4: guardian of the epigenetic galaxy. Blood. 2018 Oct 4;132(14):1468-1469. (PubMed)

Bustamante MF, Oliveira PG, Garcia-Carbonell R, Croft AP, Smith JM, Serrano RL, Sanchez-Lopez E, Liu X, Kisseleva T, Hay N, Buckley CD, Firestein GS, Murphy AN, Miyamoto S, Guma M. Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis. Ann Rheum Dis. 2018 Nov;77(11):1636-1643. (PubMed)

Canestrari E, Paroo Z. Ribonucleases as Drug Targets. Trends Pharmacol Sci. 2018 Oct;39(10):855-866. Review. (PubMed)

Cedernaes J, Ramsey KM, Bass J. 2018. The Role of Circadian Biology in Health and Disease. In: J. Larry Jameson, Sr. Editor, Harrison’s Principles of Internal Medicine, 20th edition, vol.2 pp. 3504-3515. (accessmedicine.mhmedical.com)

Chai H, Jiang H, Lin L, Liu L. A marginalized two-part Beta regression model for microbiome compositional data. PLoS Comput Biol. 2018 Jul 23;14(7):e1006329. eCollection 2018 Jul. (PubMed)

Chattopadhyay I, Kiciman E, Elliott JW, Shaman JL, Rzhetsky A. Conjunction of factors triggering waves of seasonal influenza. Elife. 2018 Feb 27;7. (PubMed)

Chen C, Meng Q, Xia Y, Ding C, Wang L, Dai R, Cheng L, Gunaratne P, Gibbs RA, Min S, Coarfa C, Reid JG, Zhang C, Jiao C, Jiang Y, Giase G, Thomas A, Fitzgerald D, Brunetti T, Shieh A, Xia C, Wang Y, Wang Y, Badner JA, Gershon ES, White KP, Liu C. The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders. Sci Transl Med. 2018 Dec 19;10(472). (PubMed)

Chen H, Cade BE, Gleason KJ, (…) Bell GI, (…) Redline S. Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men. Am J Respir Cell Mol Biol. 2018 Mar;58(3):391-401. (PubMed)

Chen J, Sathiyamoorthy K, Zhang X, Schaller S, Perez White BE, Jardetzky TS, Longnecker R. Ephrin receptor A2 is a functional entry receptor for Epstein-Barr virus. Nat Microbiol. 2018 Feb;3(2):172-180. (PubMed)

Chen Z, D’Arc Oliveira S, Zimnicka AM, Jiang Y, Sharma T, Chen S, Lazarov O, Bonini MG, Haus JM, Minshall RD. Reciprocal Regulation of eNOS and Caveolin-1 Functions in Endothelial Cells. Mol Biol Cell. 2018 May 15;29(10):1190-1202. (PubMed)

Chen Z, Notti RQ, Ueberheide BM, Ruthenburg AJ. Quantitative and structural assessment of histone methyllysine analog engagement by cognate binding proteins reveals affinity decrements relative to native counterparts. 2018 Jan 23;57(3):300-304. (PubMed)

Cheng J, Demeulemeester J, Wedge DC, Vollan HKM, Pitt JJ, Russnes HG, Pandey BP, Nilsen G, Nord S, Bignell GR, White KP, Børresen-Dale AL, Campbell PJ, Kristensen VN, Stratton MR, Lingjærde OC, Moreau Y, Van Loo P. Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors. Nat Commun. 2018 Dec 17;9(1):5397. (PubMed)

Chew J, Leypunskiy E, Lin J, Murugan A, Rust MJ. High protein copy number is required to suppress stochasticity in the cyanobacterial circadian clock. Nat Commun. 2018 Aug 1;9(1):3004. (PubMed)

Cho S, Park W, Kim H, Jokisaari JR, Roth EW, Lee S, Klie RF, Lee B, Kim DH. Gallstone-Formation-Inspired Bimetallic Supra-nanostructures for Computed-Tomography-Image-Guided Radiation Therapy. ACS Appl. Nano Mater. 2018 1;(9):4602–4611. (pubs.acs.org)

Chu BTT, Petrovich ML, Chaudhary A, Wright D, Murphy B, Wells G, Poretsky R. Metagenomic analysis reveals the impact of wastewater treatment plants on the dispersal of microorganisms and genes in aquatic sediments. Appl Environ Microbiol. 2018 Feb 14;84(5). (PubMed)

Cleary JL, Kolachina S, Wolfe BE, Sanchez LM. Coproporphyrin III Produced by the Bacterium Glutamicibacter arilaitensis Binds Zinc and Is Upregulated by Fungi in Cheese Rinds. mSystems. 2018 Aug 21;3(4). eCollection 2018 Jul-Aug. (PubMed)

Cleary JL, Sanchez LM. Large scale MALDI-TOF imaging of metabolites from filamentous fungi. 2018. Bruker Daltonics. (Online)

Clevenger KD, Ye R, Bok JW, Thomas PM, Islam MN, Miley GP, Robey M, Chen C, Yang K, Swyers M, Wu E, Gao P, Wu C, Keller NP, Kelleher NL. Interrogation of Benzomalvin Biosynthesis using FAC-MS: Discovery of a Benzodiazepine Synthase Activity. Biochemistry. 2018 Jun 12;57(23):3237-3243. (PubMed)

Compton PD, Kelleher NL, Gunawardena J. Estimating the Distribution of Protein Post-Translational Modification States by Mass Spectrometry. J Proteome Res. 2018 Aug 3;17(8):2727-2734. (PubMed)

Condello S, Sima L, Ivan C, Cardenas H, Schiltz G, Mishra RK, Matei D. Tissue Tranglutaminase Regulates Interactions between Ovarian Cancer Stem Cells and the Tumor Niche. Cancer Res. 2018 Jun 1;78(11):2990-3001. (PubMed)

Cook LC, Hu H, Maienschein-Cline M, Federle MJ. A vaginal tract signal detected by the GBS SaeRS system elicits transcriptomic changes and enhances murine colonization. Infect Immun. 2018 Mar 22;86(4). (PubMed)

D’Aquino AE, Kim DS, Jewett MC. Engineered Ribosomes for Basic Science and Synthetic Biology. Annu Rev Chem Biomol Eng. 2018 Jun 7;9:311-340. (PubMed)

David BP, Dubrovskyi O, Speltz TE, Wolff JJ, Frasor J, Sanchez LM, Moore TW. Using Tumor Explants for Imaging Mass Spectrometry Visualization of Unlabeled Peptides and Small Molecules. ACS Med. Chem. Lett. 2018 May 17;9(7):768-772. (PubMed)

Davis RG, Park HM, Kim K, Greer JB, Fellers RT, LeDuc RD, Romanova EV, Rubakhin SS, Zombeck JA, Wu C, Yau PM, Gao P, van Nispen AJ, Patrie SM, Thomas PM, Sweedler JV, Rhodes JS, Kelleher NL. Top-Down Proteomics Enables Comparative Analysis of Brain Proteoforms Between Mouse Strains. Anal Chem. 2018 Mar 20;90(6):3802-3810. (PubMed)

Davis-Roca AC, Divekar NS, Ng RK, Wignall SM. Dynamic SUMO remodeling drives a series of critical events during the meiotic divisions in Caenorhabditis elegans. PLoS Genet. 2018 Sep 4;14(9):e1007626. eCollection 2018 Sep. (PubMed)

de Paz AM, Cybulski TR, Marblestone AH, Zamft BM, Church GM, Boyden ES, Kording KP, Tyo KEJ. High-resolution mapping of DNA polymerase fidelity using nucleotide imbalances and next-generation sequencing. Nucleic Acids Res. 2018 Jul 27;46(13):e78. (PubMed)

Dehn S, Thorp EB. Myeloid receptor CD36 is required for early phagocytosis of myocardial infarcts and induction of Nr4a1-dependent mechanisms of cardiac repair. FASEB J. 2018 Jan;32(1):254-264. (PubMed)

DeWaal D, Nogueira V, Terry AR, Patra KC, Jeon SM, Guzman G, Au J, Long CP, Antoniewicz MR, Hay N. Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin. Nat Commun. 2018 Jan 31;9(1):446. Erratum in: Nat Commun. 2018 Jun 26;9(1):2539. (PubMed)

Dong H, Zhu M, Meng L, Ding Y, Yang D, Zhang S, Qiang W, Fisher DW, Xu EY. Pumilio2 regulates synaptic plasticity via translational repression of synaptic receptors in mice. Oncotarget. 2018 Jan 30;9(63):32134-32148. eCollection 2018 Aug 14. (PubMed)

Du F, Bobbala S, Yi S, Scott EA. Sequential intracellular release of water-soluble cargos from Shell-crosslinked polymersomes. J Control Release. 2018 Jul 28;282:90-100. (PubMed)

Du JS, Chen PC, Meckes B, Kluender EJ, Xie Z, Dravid VP, Mirkin CA. Windowless Observation of Evaporation-Induced Coarsening of Au-Pt Nanoparticles in Polymer Nanoreactors. J Am Chem Soc. 2018 Jun 13;140(23):7213-7221. (PubMed)

Du JS, Chen PC, Meckes B, Xie Z, Zhu J, Liu Y, Dravid VP, Mirkin CA. Corrigendum: The Structural Fate of Individual Multicomponent Metal-Oxide Nanoparticles in Polymer Nanoreactors. Angew Chem Int Ed Engl. 2018 May 22;57(21):5977. (PubMed)

Du X, Gomez CM. Erratum to: Spinocerebellar Ataxia Type 6: Molecular Mechanisms and Calcium Channel Genetics. Adv Exp Med Biol. 2018;1049:E1. (PubMed)

Emmanuel AO, Arnovitz S, Haghi L, Mathur PS, Mondal S, Quandt J, Okoreeh MK, Maienschein-Cline M, Khazaie K, Dose M, Gounari F. TCF-1 and HEB cooperate to establish the epigenetic and transcription profiles of CD4+CD8+ thymocytes. Nat Immunol. 2018 Dec;19(12):1366-1378. (PubMed)

Erbaş A, de la Cruz MO, Marko JF. Effects of electrostatic interactions on ligand dissociation kinetics. Phys Rev E. 2018 Feb;97(2-1):022405. (PubMed)

Eshein A, Li Y, Dong B, Almassalha LM, Chandler JE, Nguyen TQ, Hujsak KA, Dravid VP, Sun C, Zhang HF, Backman V. Sub-10-nm imaging of nucleic acids using spectroscopic intrinsic-contrast photon-localization optical nanoscopy (SICLON). Opt Lett. 2018 Dec 1;43(23):5817-5820. (PubMed)

Evans KS, Brady SC, Bloom JS, Tanny RE, Cook DE, Giuliani SE, Hippleheuser SW, Zamanian M, Andersen EC. Shared genomic regions underlie natural variation in diverse toxin responses. Genetics. 2018 Dec;210(4):1509-1525. (PubMed)

Figueroa KP, Gan SR, Perlman S, Wilmot G, Gomez CM, Schmahmann J, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Pulst SM, Kuo SH. C9orf72 repeat expansions as genetic modifiers for depression in spinocerebellar ataxias. Mov Disord. 2018 Mar;33(3):497-498. (PubMed)

Firlar E, Ouy M, Bogdanowicz A, Covnot L, Song B, Nadkarni Y, Shahbazian-Yassar R, Shokuhfar T. Investigation of the Magnetosome Biomineralization in Magnetotactic Bacteria Using GLC-TEM. Microsc. Microanal. Volume 24, Supplement S1 (Proceedings of Microscopy & Microanalysis 2018) August 2018 pp. 1330-1331. (doi.org)

Fisher DW, Han Y, Lyman KA, Heuermann RJ, Bean LA, Ybarra N, Foote KM, Dong H, Nicholson DA, Chetkovich DM. HCN channels in the hippocampus regulate active coping behavior. J Neurochem. 2018 Sep;146(6):753-766. (PubMed)

Fisher DW, Luu P, Agarwal N, Kurz JE, Chetkovich DM. Loss of HCN2 leads to delayed gastrointestinal motility and reduced energy intake in mice. PLoS One. 2018 Feb 21;13(2):e0193012. eCollection 2018. (PubMed)

Fisher OS, Kenney GE, Ross MO, Ro SY, Lemma BE, Batelu S, Thomas PM, Sosnowski VC, DeHart CJ, Kelleher NL, Stemmler TL, Hoffman BM, Rosenzweig AC. Characterization of a long overlooked copper protein from methane- and ammonia-oxidizing bacteria. Nat Commun. 2018 Oct 15;9(1):4276. (PubMed)

Fornelli L, Srzentić K, Huguet R, Mullen C, Sharma S, Zabrouskov V, Fellers RT, Durbin KR, Compton PD, Kelleher NL. Accurate sequence analysis of a monoclonal antibody by top-down and middle-down Orbitrap mass spectrometry applying multiple ion activation techniques. Anal Chem. 2018 Jul 17;90(14):8421-8429. (PubMed)

Fornelli L, Toby TK, Schachner LF, Doubleday PF, Srzentić K, DeHart CJ, Kelleher NL. Top-down proteomics: Where we are, where we are going? J Proteomics. 2018 Mar 20;175:3-4. (PubMed)

Freeman R, Han M, Álvarez Z, Lewis JA, Wester JR, Stephanopoulos N, McClendon MT, Lynsky C, Godbe JM, Sangji H, Luijten E, Stupp SI. Reversible self-assembly of superstructured networks. Science. 2018 Nov 16;362(6416):808-813. (PubMed)

Galey MM, Sanchez LM. Spatial Analyses of Specialized Metabolites: The Key to Studying Function in Hosts. mSystems. Mar 2018, 3 (2) e00148-17. (PubMed)

Gandal MJ, Haney JR, Parikshak NN, Leppa V, Ramaswami G, Hartl C, Schork AJ, Appadurai V, Buil A, Werge TM, Liu C, White KP; CommonMind Consortium; PsychENCODE Consortium; iPSYCH-BROAD Working Group, Horvath S, Geschwind DH. Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap. Science. 2018 Feb 9;359(6376):693-697. (PubMed)

Gaskell H, Ge X, Nieto N. High-Mobility Group Box-1 and Liver Disease. Hepatol Commun. 2018 Sep 7;2(9):1005-1020. eCollection 2018 Sep. Review. (PubMed)

Gatto RG, Amin MY, Deyoung D, Hey M, Mareci TH, Magin RL. Ultra-High Field Diffusion MRI Reveals Early Axonal Pathology in Spinal Cord of ALS mice. Transl Neurodegener. 2018 Aug 8;7:20. eCollection 2018. (PubMed)

Gatto RG, Li W, Gao J, Magin RL. In vivo diffusion MRI detects early spinal cord axonal pathology in a mouse model of amyotrophic lateral sclerosis. First published: 26 June 2018. NMR Biomed. 2018 Aug;31(8):e3954. (PubMed)

Gatto RG, Li W, Magin RL. Diffusion Tensor Imaging Identifies Presymptomatic Axonal Degeneration in the Spinal Cord of ALS Mice. Brain Res. 2018 Jan 15;1679:45-52. (PubMed)

Ge X, Arriazu E, Magdaleno F, Antoine DJ, Dela Cruz R, Theise N, Nieto N. High mobility group box-1 drives fibrosis progression signaling via the receptor for advanced glycation end-products in mice. Hepatology. 2018 Dec;68(6):2380-2404. (PubMed)

Geeleher P, Nath A, Wang F, Zhang Z, Barbeira AN, Fessler J, Grossman RL, Seoighe C, Stephanie Huang R. Cancer expression quantitative trait loci (eQTLs) can be determined from heterogeneous tumor gene expression data by modeling variation in tumor purity. Genome Biol. 2018 Sep 11;19(1):130. (PubMed)

Gerbasi VR, Browne CM, Samir P, Shen B, Sun M, Hazelbaker DZ, Galassie AC, Frank J, Link AJ. Critical Role for Saccharomyces cerevisiae Asc1p in Translational Initiation at Elevated Temperatures. Proteomics. 2018 Dec;18(23):e1800208. (PubMed)

Gibcus JH, Samejima K, Goloborodko A, Samejima I, Naumova N, Nuebler J, Kanemaki MT, Xie L, Paulson JR, Earnshaw WC, Mirny LA, Dekker J. A pathway for mitotic chromosome formation. Science. 2018 Feb 9;359(6376). (PubMed)

Gladstein S, Stawarz A, Almassalha LM, Cherkezyan L, Chandler JE, Zhou X, Subramanian H, Backman V. Measuring Nanoscale Chromatin Heterogeneity with Partial Wave Spectroscopic Microscopy. Methods Mol Biol. 2018;1745:337-360. (PubMed)

Gong Y, Lazaris C, Sakellaropoulos T, Lozano A, Kambadur P, Ntziachristos P, Aifantis I, Tsirigos A. Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries. Nat Commun. 2018 Feb 7;9(1):542. (PubMed)

Gorman K, McGinnis J, Kay B. Generating FN3‐Based Affinity Reagents Through Phage Display. Curr Protoc Chem Biol. 2018 Jun;10(2):e39. (PubMed)

Gray CL, Lobdell DT, Rappazzo KM, Jian Y, Jagai JS, Messer LC, Patel AP, DeFlorio-Barker SA, Lyttle C, Solway J, Rzhetsky A. Associations between environmental quality and adult asthma prevalence in medical claims data. Environ Res. 2018 Oct;166:529-536. (PubMed)

Greeley SAW, Letourneau LR, Philipson LH. Precision medicine in KCNJ11 permanent neonatal diabetes. Lancet Diabetes Endocrinol. 2018 Aug;6(8):594-595. (PubMed)

Gruppuso PA, Boylan JM, Zabala V, Neretti N, Abshiru NA, Sikora JW, Doud EH, Camarillo JM, Thomas PM, Kelleher NL, Sanders JA. Stability of histone post-translational modifications in samples derived from liver tissue and primary hepatic cells. PLoS One. 2018 Sep 7;13(9):e0203351. eCollection 2018. (PubMed)

Gunn KH, Marko JF, Mondragón A. Single-Molecule Magnetic Tweezer Analysis of Topoisomerases. Methods Mol Biol. 2018;1703:139-152. (PubMed)

Gupta A, Xu J, Lee S, Tsai ST, Zhou B, Kurosawa K, Werner MS, Koide A, Ruthenburg AJ, Dou Y, Koide S. Facile target validation in an animal model with intracellularly expressed monobodies. Nat Chem Biol. 2018 Sep;14(9):895-900. (PubMed)

Haber A, Molnar F, Motter AE. State observation and sensor selection for nonlinear networks. IEEE Trans Control Netw Syst. 2018 Jun;5(2):694-708. (PubMed)

Han Y, Yan C, Fishbain S, Ivanov I, He Y. Structural visualization of RNA polymerase III transcription machineries. Cell Discov. 2018 Jul 31;4:40. eCollection 2018. (PubMed)

Harris AG, Letourneau LR, Greeley SAW. Monogenic diabetes: the impact of making the right diagnosis. Curr Opin Pediatr. 2018 Aug;30(4):558-567. (PubMed)

Harris D, Lukoyanov D, Shaw S, Compton PD, Tokmina-Lukaszewska M, Bothner B, Kelleher NL, Dean DR, Hoffman BM, Seefeldt LC. The Mechanism of N2 Reduction Catalyzed by Fe-Nitrogenase Involves Reductive Elimination of H2. Biochemistry. 2018 Feb 6;57(5):701-710. (PubMed)

Hattersley AT, Greeley SAW, Polak M, Rubio-Cabezas O, Njølstad PR, Mlynarski W, Castano L, Carlsson A, Raile K, Chi DV, Ellard S, Craig ME. ISPAD Clinical Practice Consensus Guidelines 2018: The diagnosis and management of monogenic diabetes in children and adolescents. Pediatr Diabetes. 2018 Oct;19 Suppl 27:47-63. (PubMed)

Heys JG, Dombeck DA. Evidence for a subcircuit in medial entorhinal cortex representing elapsed time during immobility. Nat Neurosci. 2018 Nov;21(11):1574-1582. (PubMed)

Hockenberry AJ, Jewett MC, Amaral LAN, Wilke CO. Within-Gene Shine-Dalgarno Sequences Are Not Selected for Function. Mol Biol Evol. 2018 Oct 1;35(10):2487-2498. (PubMed)

Hong BJ, Iscen A, Chipre AJ, Li MM, Lee OS, Leonard JN, Schatz GC, Nguyen ST. Highly Stable, Ultra-Small Polymer-Grafted Nanobins (usPGNs) with Stimuli-Responsive Capability. J Phys Chem Lett. 2018 Mar 1;9(5):1133-1139. (PubMed)

Hong HK, Maury E, Ramsey KM, Perelis M, Marcheva B, Omura C, Kobayashi Y, Guttridge DC, Barish GD, Bass J. Requirement for NF-κB in maintenance of molecular and behavioral circadian rhythms in mice. Genes Dev. 2018 Nov 1;32(21-22):1367-1379. (PubMed)

Hong L, Vani BP, Thiede EH, Rust MJ, Dinner AR. Molecular dynamics simulations of nucleotide release from the circadian clock protein KaiC reveal atomic-resolution functional insights. Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):E11475-E11484. (PubMed)

Hwang JL, Park SY, Ye H, Sanyoura M, Pastore AN, Carmody D, Del Gaudio D, Wilson JF, Hanis CL, Liu X, Atzmon G, Glaser B, Philipson LH, Greeley SAW; T2D-Genes Consortium. FOXP3 mutations causing early-onset insulin-requiring diabetes but without other features of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome. Pediatr Diabetes. 2018 May;19(3):388-392. (PubMed)

Ishihara J, Ishihara A, Fukunaga K, Sasaki K, White MJV, Briquez PS, Hubbell JA. Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing. Nat Commun. 2018 Jun 4;9(1):2163. (PubMed)

Jackobel AJ, Han Y, He Y, Knutson BA. Breaking the mold: structures of the RNA polymerase I transcription complex reveal a new path for initiation. Transcription. 2018;9(4):255-261. (PubMed)

Jeon SM, Hay N. Expanding the concepts of cancer metabolism. Exp Mol Med. 2018 Apr 16;50(4):32. (PubMed)

Jun G, Manning A, Almeida M, (…) Bell GI, (…) Blangero J. Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):379-384. (PubMed)

Kam CY, Dubash AD, Magistrati E, Polo S, Satchell KJF, Sheikh F, Lampe PD, Green KJ. Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43. J Cell Biol. 2018 Sep 3;217(9):3219-3235. (PubMed)

Kanis MJ, Qiang W, Pineda M, Maniar KP, Kim JJ. A small molecule inhibitor of the perinucleolar compartment, ML246, attenuates growth and spread of ovarian cancer. Gynecol Oncol Res Pract. 2018 Oct 2;5:7. eCollection 2018. (PubMed)

Karabin NB, Allen S, Kwon HK, Bobbala S, Firlar E, Shokuhfar T, Shull KR, Scott EA. Sustained micellar delivery via inducible transitions in nanostructure morphology. Nat Commun. 2018 Feb 12;9(1):624. (PubMed)

Karki S, Kennedy DE, Mclean K, Grzybowski AT, Maienschein-Cline M, Banerjee S, Xu H, Davis E, Mandal M, Labno C, Powers SE, Le Beau MM, Dinner AR, Singh H, Ruthenburg AJ, Clark MR. Regulated Capture of Vκ Gene Topologically Associating Domains by Transcription Factories. Cell Rep. 2018 Aug 28;24(9):2443-2456. (PubMed)

Kathayat RS, Cao Y, Elvira PD, Sandoz PA, Zaballa ME, Springer MZ, Drake LE, Macleod KF, van der Goot FG, Dickinson BC. Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes. Nat Commun. 2018 Jan 23;9(1):334. (PubMed)

Kenney GE, Dassama LMK, Pandelia ME, Gizzi AS, Martinie RJ, Gao P, DeHart CJ, Schachner LF, Skinner OS, Ro SY, Zhu X, Sadek M, Thomas PM, Almo SC, Bollinger JM Jr., Krebs C, Kelleher NL, Rosenzweig AC. The biosynthesis of methanobactin. Science. 2018 Mar 23;359(6382):1411-1416. (PubMed)

Kerr D, Tietjen GT, Gong Z, Tajkhorshid E, Adams EJ, Lee KYC. Sensitivity of peripheral membrane proteins to the membrane context: A case study of phosphatidylserine and the TIM proteins. Biochim Biophys Acta Biomembr. Review. 2018 Oct;1860(10):2126-2133. (PubMed)

Khramtsova EA, Heldman R, Derks EM, Yu D; Tourette Syndrome/Obsessive-Compulsive Disorder Working Group of the Psychiatric Genomics Consortium, Davis LK, Stranger BE. Sex differences in the genetic architecture of obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet. 2018 Nov 20. [Epub ahead of print] (PubMed)

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