CBC-Funded Publications 2018

Updated: November 10, 2018

As of October 2018, over 2180 research papers have been published as a result of CBC funding.


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2018

Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, Ivanov AR, Jensen ON, Jewett MC, Kelleher NL, Kiessling LL, Krogan NJ, Larsen MR, Loo JA, Ogorzalek Loo RR, Lundberg E, MacCoss MJ, Mallick P, Mootha VK, Mrksich M, Muir TW, Patrie SM, Pesavento JJ, Pitteri SJ, Rodriguez H, Saghatelian A, Sandoval W, Schlüter H, Sechi S, Slavoff SA, Smith LM, Snyder MP, Thomas PM, Uhlén M, Van Eyk JE, Vidal M, Walt DR, White FM, Williams ER, Wohlschlager T, Wysocki VH, Yates NA, Young NL, Zhang B. How many human proteoforms are there? Nat Chem Biol. 2018 Feb 14;14(3):206-214. (PubMed)

Allen SD, Bobbala S, Karabin N, Modak M, Scott EA. Benchmarking bicontinuous nanospheres against polymersomes for in vivo biodistribution and dual intracellular delivery of lipophilic and water soluble payloads. ACS Appl Mater Interfaces. 2018 Sep 14. [Epub ahead of print] (PubMed)

Allen SD, Liu YG, Bobbala S, Cai L, Hecker PI, Temel R, Scott EA. Polymersomes scalably fabricated via flash nanoprecipitation are non-toxic in non-human primates and associate with leukocytes in the spleen and kidney following intravenous administration. Nano Research. 2018 Apr. 7. [Epub ahead of print] (springer.com)

Alvares K, DeHart CJ, Thomas PM, Kelleher NL, Veis A. The unique biomineralization transcriptome and proteome of Lytechinus variegatus teeth. Connect Tissue Res. 2018 Dec;59(sup1):20-29. (PubMed)

Bailey LJ, Sheehy KM, Dominik PK, Liang WG, Rui H, Clark M, Jaskolowski M, Kim Y, Deneka D, Tang WJ, Kossiakoff AA. Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination. J Mol Biol. 2018 Feb 2;430(3):337-347. (PubMed)

Beaubier N, Tell R, Huether R, Bontrager M, Bush S, Parsons J, Shah K, Baker T, Selkov G, Taxter T, Thomas A, Bettis S, Khan A, Lau D, Lee C, Barber M, Cieslik M, Frankenberger C, Franzen A, Weiner A, Palmer G, Lonigro R, Robinson D, Wu YM, Cao X, Lefkofsky E, Chinnaiyan A, White KP. Clinical validation of the Tempus xO assay. Oncotarget. 2018 May 25;9(40):25826-25832. eCollection 2018 May 25. (PubMed)

Bennett RL, Licht JD. Targeting Epigenetics in Cancer. Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:187-207. (PubMed)

Bhuripanyo K, Yiyang Wang Y, Liu X, Zhou L, Liu R, Duong D, Zhao B, Bi Y, Zhou H, Chen G, Seyfried NT, Chazin WJ, Kiyokawa H, Yin J. Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer. Sci Adv. 2018 Jan 3;4(1):e1701393. (PubMed)

Biancucci M, Minasov G, Banerjee A, Herrera A, Woida PJ, Kieffer MB, Bindu L, Abreu-Blanco M, Anderson WF, Gaponenko V, Stephen AG, Holderfield M, Satchell KJF. The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling. Sci Signal. 2018 Oct 2;11(550). (PubMed)

Briscoe SD, Albertin CB, Rowell JJ, Ragsdale CW. Neocortical Association Cell Types in the Forebrain of Birds and Alligators. Curr Biol. 2018 Mar 5;28(5):686-696.e6. (PubMed)

Bryois J, Garrett ME, Song L, Safi A, Giusti-Rodriguez P, Johnson GD, Shieh AW, Buil A, Fullard JF, Roussos P, Sklar P, Akbarian S, Haroutunian V, Stockmeier CA, Wray GA, White KP, Liu C, Reddy TE, Ashley-Koch A, Sullivan PF, Crawford GE. Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia. Nat Commun. 2018 Aug 7;9(1):3121. (PubMed)

Canestrari E, Paroo Z. Ribonucleases as Drug Targets. Trends Pharmacol Sci. 2018 Aug 22. Review. [Epub ahead of print] (PubMed)

Chattopadhyay I, Kiciman E, Elliott JW, Shaman JL, Rzhetsky A. Conjunction of factors triggering waves of seasonal influenza. Elife. 2018 Feb 27;7. (PubMed)

Chen H, Cade BE, Gleason KJ, (…) Bell GI, (…) Redline S. Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men. Am J Respir Cell Mol Biol. 2018 Mar;58(3):391-401. (PubMed)

Chen J, Sathiyamoorthy K, Zhang X, Schaller S, Perez White BE, Jardetzky TS, Longnecker R. Ephrin receptor A2 is a functional entry receptor for Epstein-Barr virus. Nat Microbiol. 2018 Feb;3(2):172-180. (PubMed)

Chen Z, D’Arc Oliveira S, Zimnicka AM, Jiang Y, Sharma T, Chen S, Lazarov O, Bonini MG, Haus JM, Minshall RD. Reciprocal Regulation of eNOS and Caveolin-1 Functions in Endothelial Cells. Mol Biol Cell. 2018 Mar 21. [Epub ahead of print] (PubMed)

Chen Z, Notti RQ, Ueberheide BM, Ruthenburg AJ. Quantitative and structural assessment of histone methyllysine analog engagement by cognate binding proteins reveals affinity decrements relative to native counterparts. Biochemistry. 2018 Jan 23;57(3):300-304. (PubMed)

Chew J, Leypunskiy E, Lin J, Murugan A, Rust MJ. High protein copy number is required to suppress stochasticity in the cyanobacterial circadian clock. Nat Commun. 2018 Aug 1;9(1):3004. (PubMed)

Cho S, Park W, Kim H, Jokisaari JR, Roth EW, Lee S, Klie RF, Lee B, Kim DH. Gallstone-Formation-Inspired Bimetallic Supra-nanostructures for Computed-Tomography-Image-Guided Radiation Therapy. ACS Appl. Nano Mater. Publication Date (Web): August 6, 2018. [Epub ahead of print] (pubs.acs.org)

Chu BTT, Petrovich ML, Chaudhary A, Wright D, Murphy B, Wells G, Poretsky R. Metagenomic analysis reveals the impact of wastewater treatment plants on the dispersal of microorganisms and genes in aquatic sediments. Appl Environ Microbiol. 2018 Feb 14;84(5). (PubMed)

Cleary JL, Kolachina S, Wolfe BE, Sanchez LM. Coproporphyrin III Produced by the Bacterium Glutamicibacter arilaitensis Binds Zinc and Is Upregulated by Fungi in Cheese Rinds. mSystems. 2018 Aug 21;3(4). eCollection 2018 Jul-Aug. (PubMed)

Clevenger KD, Ye R, Bok JW, Thomas PM, Islam MN, Miley GP, Robey M, Chen C, Yang K, Swyers M, Wu E, Gao P, Wu C, Keller NP, Kelleher NL. Interrogation of Benzomalvin Biosynthesis using FAC-MS: Discovery of a Benzodiazepine Synthase Activity. Biochemistry. 2018 Mar 13. [Epub ahead of print] (PubMed)

Compton PD, Kelleher NL, Gunawardena J. Estimating the Distribution of Protein Post-Translational Modification States by Mass Spectrometry. J Proteome Res. 2018 Jul 10. [Epub ahead of print] (PubMed)

Cook LC, Hu H, Maienschein-Cline M, Federle MJ. A vaginal tract signal detected by the GBS SaeRS system elicits transcriptomic changes and enhances murine colonization. Infect Immun. 2018 Mar 22;86(4). (PubMed)

David BP, Dubrovskyi O, Speltz TE, Wolff JJ, Frasor J, Sanchez LM, Moore TW. Using Tumor Explants for Imaging Mass Spectrometry Visualization of Unlabeled Peptides and Small Molecules. ACS Med. Chem. Lett. 2018 May 17;9(7):768-772. (PubMed)

Davis RG, Park HM, Kim K, Greer JB, Fellers RT, LeDuc RD, Romanova EV, Rubakhin SS, Zombeck JA, Wu C, Yau PM, Gao P, van Nispen AJ, Patrie SM, Thomas PM, Sweedler JV, Rhodes JS, Kelleher NL. Top-Down Proteomics Enables Comparative Analysis of Brain Proteoforms Between Mouse Strains. Anal Chem. 2018 Mar 20;90(6):3802-3810. (PubMed)

Davis-Roca AC, Divekar NS, Ng RK, Wignall SM. Dynamic SUMO remodeling drives a series of critical events during the meiotic divisions in Caenorhabditis elegans. PLoS Genet. 2018 Sep 4;14(9):e1007626. eCollection 2018 Sep. (PubMed)

de Paz AM, Cybulski TR, Marblestone AH, Zamft BM, Church GM, Boyden ES, Kording KP, Tyo KEJ. High-resolution mapping of DNA polymerase fidelity using nucleotide imbalances and next-generation sequencing. Nucleic Acids Research. 2018. Published: 30 April 2018. (doi.org)

Dehn S, Thorp EB. Myeloid receptor CD36 is required for early phagocytosis of myocardial infarcts and induction of Nr4a1-dependent mechanisms of cardiac repair. FASEB J. 2018 Jan;32(1):254-264. (PubMed)

Dhiman VK, Bolt MJ, White KP. Nuclear receptors in cancer – uncovering new and evolving roles through genomic analysis. Nat Rev Genet. 2018 Mar;19(3):160-174. Review. (PubMed)

Du JS, Chen PC, Meckes B, Kluender EJ, Xie Z, Dravid VP, Mirkin CA. Windowless Observation of Evaporation-Induced Coarsening of Au-Pt Nanoparticles in Polymer Nanoreactors. J Am Chem Soc. 2018 Jun 13;140(23):7213-7221. (PubMed)

Du JS, Chen PC, Meckes B, Xie Z, Zhu J, Liu Y, Dravid VP, Mirkin CA. Corrigendum: The Structural Fate of Individual Multicomponent Metal-Oxide Nanoparticles in Polymer Nanoreactors. Angew Chem Int Ed Engl. 2018 May 22;57(21):5977. (PubMed)

Erbaş A, de la Cruz MO, Marko JF. Effects of electrostatic interactions on ligand dissociation kinetics. Phys Rev E. 2018 Feb;97(2-1):022405. (PubMed)

Evans KS, Brady SC, Bloom JS, Tanny RE, Cook DE, Giuliani SE, Hippleheuser SW, Zamanian M, Andersen EC. Common genomic regions underlie natural variation in diverse toxin responses. bioRxiv preprint first posted online May. 17, 2018. [Epub ahead of print] (doi.org)

Firlar E, Ouy M, Bogdanowicz A, Covnot L, Song B, Nadkarni Y, Shahbazian-Yassar R, Shokuhfar T. Investigation of the Magnetosome Biomineralization in Magnetotactic Bacteria Using GLC-TEM. Microsc. Microanal. 24 (Suppl 1), 2018. [Epub ahead of print] (doi.org)

Fisher DW, Han Y, Lyman KA, Heuermann RJ, Bean LA, Ybarra N, Foote KM, Dong H, Nicholson DA, Chetkovich DM. HCN channels in the hippocampus regulate active coping behavior. J Neurochem. 2018 Jun 28. [Epub ahead of print] (PubMed)

Fisher DW, Luu P, Agarwal N, Kurz JE, Chetkovich DM. Loss of HCN2 leads to delayed gastrointestinal motility and reduced energy intake in mice. PLoS One. 2018 Feb 21;13(2):e0193012. eCollection 2018. (PubMed)

Fisher OS, Kenney GE, Ross MO, Ro SY, Lemma BE, Batelu S, Thomas PM, Sosnowski VC, DeHart CJ, Kelleher NL, Stemmler TL, Hoffman BM, Rosenzweig AC. Characterization of a long overlooked copper protein from methane- and ammonia-oxidizing bacteria. Nat Commun. 2018 Oct 15;9(1):4276. (PubMed)

Fornelli L, Srzentić K, Huguet R, Mullen C, Sharma S, Zabrouskov V, Fellers RT, Durbin KR, Compton PD, Kelleher NL. Accurate sequence analysis of a monoclonal antibody by top-down and middle-down Orbitrap mass spectrometry applying multiple ion activation techniques. Anal Chem. 2018 Jun 12. [Epub ahead of print] (PubMed)

Fornelli L, Toby TK, Schachner LF, Doubleday PF, Srzentić K, DeHart CJ, Kelleher NL. Top-down proteomics: Where we are, where we are going? J Proteomics. 2018 Mar 20;175:3-4. (PubMed)

Galey MM, Sanchez LM. Spatial Analyses of Specialized Metabolites: The Key to Studying Function in Hosts. mSystems. Mar 2018, 3 (2) e00148-17. (PubMed)

Gandal MJ, Haney JR, Parikshak NN, Leppa V, Ramaswami G, Hartl C, Schork AJ, Appadurai V, Buil A, Werge TM, Liu C, White KP; CommonMind Consortium; PsychENCODE Consortium; iPSYCH-BROAD Working Group, Horvath S, Geschwind DH. Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap. Science. 2018 Feb 9;359(6376):693-697. (PubMed)

Gaskell H, Ge X, Nieto N. High-Mobility Group Box-1 and Liver Disease. Hepatol Commun. 2018 Sep 7;2(9):1005-1020. eCollection 2018 Sep. Review. (PubMed)

Gatto RG, Amin MY, Deyoung D, Hey M, Mareci TH, Magin RL. Ultra-High Field Diffusion MRI Reveals Early Axonal Pathology in Spinal Cord of ALS mice. Transl Neurodegener. 2018 Aug 8;7:20. eCollection 2018. (PubMed)

Gatto RG, Li W, Gao J, Magin RL. In vivo diffusion MRI detects early spinal cord axonal pathology in a mouse model of amyotrophic lateral sclerosis. First published: 26 June 2018. NMR in Biomedicine. 31:8. [Epub ahead of print] (onlinelibrary.wiley.com)

Gatto RG, Li W, Magin RL. Diffusion Tensor Imaging Identifies Presymptomatic Axonal Degeneration in the Spinal Cord of ALS Mice. Brain Res. 2018 Jan 15;1679:45-52. (PubMed)

Ge X, Arriazu E, Magdaleno F, Antoine DJ, Dela Cruz R, Theise N, Nieto N. High mobility group box-1 drives fibrosis progression signaling via the receptor for advanced glycation end-products in mice. Hepatology. 2018 May 18. [Epub ahead of print] (PubMed)

Geeleher P, Nath A, Wang F, Zhang Z, Barbeira AN, Fessler J, Grossman RL, Seoighe C, Stephanie Huang R. Cancer expression quantitative trait loci (eQTLs) can be determined from heterogeneous tumor gene expression data by modeling variation in tumor purity. Genome Biol. 2018 Sep 11;19(1):130. (PubMed)

Gerbasi VR, Browne CM, Samir P, Shen B, Sun M, Hazelbaker DZ, Galassie AC, Frank J, Link AJ. Critical Role for Saccharomyces cerevisiae Asc1p in Translational Initiation at Elevated Temperatures. Proteomics. 2018 Oct 4:e1800208. [Epub ahead of print] (PubMed)

Ghadge GD, Kay BK, Drigotas C, Roos RP. Single chain variable fragment antibodies directed against SOD1 ameliorate disease in mutant SOD1 transgenic mice. Neurobiol Dis. 2018 Aug 31. [Epub ahead of print] (PubMed)

Gibcus JH, Samejima K, Goloborodko A, Samejima I, Naumova N, Nuebler J, Kanemaki MT, Xie L, Paulson JR, Earnshaw WC, Mirny LA, Dekker J. A pathway for mitotic chromosome formation. Science. 2018 Feb 9;359(6376). (PubMed)

Gladstein S, Stawarz A, Almassalha LM, Cherkezyan L, Chandler JE, Zhou X, Subramanian H, Backman V. Measuring Nanoscale Chromatin Heterogeneity with Partial Wave Spectroscopic Microscopy. Methods Mol Biol. 2018;1745:337-360. (PubMed)

Gong Y, Lazaris C, Sakellaropoulos T, Lozano A, Kambadur P, Ntziachristos P, Aifantis I, Tsirigos A. Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries. Nat Commun. 2018 Feb 7;9(1):542. (PubMed)

Gorman K, McGinnis J, Kay B. Generating FN3‐Based Affinity Reagents Through Phage Display. Current Protocols in Chemical Biology, 2018. First Published: 07 June 2018. (onlinelibrary.wiley.com)

Gruppuso PA, Boylan JM, Zabala V, Neretti N, Abshiru NA, Sikora JW, Doud EH, Camarillo JM, Thomas PM, Kelleher NL, Sanders JA. Stability of histone post-translational modifications in samples derived from liver tissue and primary hepatic cells. PLoS One. 2018 Sep 7;13(9):e0203351. eCollection 2018. (PubMed)

Gupta A, Xu J, Lee S, Tsai ST, Zhou B, Kurosawa K, Werner MS, Koide A, Ruthenburg AJ, Dou Y, Koide S. Facile target validation in an animal model with intracellularly expressed monobodies. Nat Chem Biol. 2018 Jul 16. [Epub ahead of print] (PubMed)

Han Y, Yan C, Fishbain S, Ivanov I, He Y. Structural visualization of RNA polymerase III transcription machineries. Cell Discov. 2018 Jul 31;4:40. eCollection 2018. (PubMed)

Harris D, Lukoyanov D, Shaw S, Compton PD, Tokmina-Lukaszewska M, Bothner B, Kelleher NL, Dean DR, Hoffman BM, Seefeldt LC. The Mechanism of N2 Reduction Catalyzed by Fe-Nitrogenase Involves Reductive Elimination of H2. Biochemistry. 2018 Feb 6;57(5):701-710. (PubMed)

Hentchel KL, Reyes Ruiz LM, Curtis PD, Fiebig A, Coleman ML, Crosson S. Genome-scale fitness profile of Caulobacter crescentus grown in natural freshwater. ISME J. 2018 Oct 8. [Epub ahead of print] (PubMed)

Heys JG, Dombeck DA. Evidence for a subcircuit in medial entorhinal cortex representing elapsed time during immobility. Nat Neurosci. 2018 Nov;21(11):1574-1582. (PubMed)

Hong BJ, Iscen A, Chipre AJ, Li MM, Lee OS, Leonard JN, Schatz GC, Nguyen ST. Highly Stable, Ultra-Small Polymer-Grafted Nanobins (usPGNs) with Stimuli-Responsive Capability. J Phys Chem Lett. 2018 Mar 1;9(5):1133-1139. (PubMed)

Ishihara J, Ishihara A, Fukunaga K, Sasaki K, White MJV, Briquez PS, Hubbell JA. Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing. Nat Commun. 2018 Jun 4;9(1):2163. (PubMed)

Jin Q, Martinez CA, Arcipowski KM, Zhu Y, Gutiérrez-Díaz BT, Wang KK, Johnson MR, Volk A, Wang F, Wu J, Grove C, Wang H, Sokirniy I, Thomas PM, Goo YA, Abshiru NA, Hijiya N, Peirs S, Vandamme N, Berx G, Goossens S, Marshall SA, Rendleman EJ, Takahashi YH, Wang L, Rawat R, Bartom ET, Collings CK, Van Vlierberghe P, Bourquin JP, Bornhauser B, Serafin V, Bresolin S, Paganin M, Accordi B, Basso G, Kelleher NL, Weinstock J, Suresh K, Crispino JD, Shilatifard A, Strikoudis A, Mantis C, Kandela I, Kelly S, Ueberheide B, Ntziachristos P. USP7 cooperates with NOTCH1 to drive the oncogenic transcriptional program in T cell leukemia. Clin Cancer Res. 2018 Sep 17. [Epub ahead of print] (PubMed)

Jun G, Manning A, Almeida M, (…) Bell GI, (…) Blangero J. Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):379-384. (PubMed)

Karabin NB, Allen S, Kwon HK, Bobbala S, Firlar E, Shokuhfar T, Shull KR, Scott EA. Sustained micellar delivery via inducible transitions in nanostructure morphology. Nat Commun. 2018 Feb 12;9(1):624. (PubMed)

Karki S, Kennedy DE, Mclean K, Grzybowski AT, Maienschein-Cline M, Banerjee S, Xu H, Davis E, Mandal M, Labno C, Powers SE, Le Beau MM, Dinner AR, Singh H, Ruthenburg AJ, Clark MR. Regulated Capture of Vκ Gene Topologically Associating Domains by Transcription Factories. Cell Rep. 2018 Aug 28;24(9):2443-2456. (PubMed)

Kathayat RS, Cao Y, Elvira PD, Sandoz PA, Zaballa ME, Springer MZ, Drake LE, Macleod KF, van der Goot FG, Dickinson BC. Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes. Nat Commun. 2018 Jan 23;9(1):334. (PubMed)

Kenney GE, Dassama LMK, Pandelia ME, Gizzi AS, Martinie RJ, Gao P, DeHart CJ, Schachner LF, Skinner OS, Ro SY, Zhu X, Sadek M, Thomas PM, Almo SC, Bollinger JM Jr., Krebs C, Kelleher NL, Rosenzweig AC. The biosynthesis of methanobactin. Science. 2018 Mar 23;359(6382):1411-1416. (PubMed)

Kerr D, Tietjen GT, Gong Z, Tajkhorshid E, Adams EJ, Lee KYC. Sensitivity of peripheral membrane proteins to the membrane context: A case study of phosphatidylserine and the TIM proteins. Biochim Biophys Acta Biomembr. 2018 Jun 16. Review. [Epub ahead of print] (PubMed)

Kim JW, Kane JR, Panek WK, Young JS, Rashidi A, Yu D, Kanojia D, Hasan T, Miska J, Gómez-Lim MA, Ulasov IV, Balyasnikova IV, Ahmed AU, Wainwright DA, Lesniak MS. A Dendritic Cell-Targeted Adenoviral Vector Facilitates Adaptive Immune Response Against Human Glioma Antigen (CMV-IE) and Prolongs Survival in a Human Glioma Tumor Model. Neurotherapeutics. 2018 Jul 19. [Epub ahead of print] (PubMed)

Koirala D, Shelke SA, Dupont M, Ruiz S, DasGupta S, Bailey LJ, Benner SA, Piccirilli JA. Affinity maturation of a portable Fab–RNA module for chaperone-assisted RNA crystallography. Nucleic Acids Res. 2018 Mar 16;46(5):2624-2635. (PubMed)

Kokoszka ME, Kall SL, Khosla S, McGinnis JE, Lavie A, Kay BK. Identification of two distinct peptide-binding pockets in the SH3 domain of human mixed-lineage kinase 3. J Biol Chem. 2018 Jul 6. [Epub ahead of print] (PubMed)

Kudron MM, Victorsen A, Gevirtzman L, Hillier LW, Fisher WW, Vafeados D, Kirkey M, Hammonds AS, Gersch J, Ammouri H, Wall ML, Moran J, Steffen D, Szynkarek M, Seabrook-Sturgis S, Jameel N, Kadaba M, Patton J, Terrell R, Corson M, Durham TJ, Park S, Samanta S, Han M, Xu J, Yan KK, Celniker SE, White KP, Ma L, Gerstein M, Reinke V, Waterston R. The modERN Resource: Genome-Wide Binding Profiles for Hundreds of Drosophila and Caenorhabditis elegans Transcription Factors. Genetics. 2018 Mar;208(3):937-949. (PubMed)

LeDuc RD, Schwämmle V, Shortreed MR, Cesnik AJ, Solntsev SK, Shaw JB, Martin MJ, Vizcaino JA, Alpi E, Danis P, Kelleher NL, Smith LM, Ge Y, Agar JN, Chamot-Rooke J, Loo JA, Pasa-Tolic L, Tsybin YO. ProForma: A Standard Proteoform Notation. J Proteome Res. 2018 Mar 2;17(3):1321-1325. (PubMed)

Leech KA, Kim HE, Hornby TG. Strategies to augment volitional and reflex function may improve locomotor capacity following incomplete spinal cord injury. J Neurophysiol. 2018 Mar 1;119(3):894-903. (PubMed)

Liang K, Smith ER, Aoi Y, Stoltz KL, Katagi H, Woodfin AR, Rendleman EJ, Marshall SA, Murray DC, Wang L, Ozark PA, Mishra RK, Hashizume R, Schiltz GE, Shilatifard A. Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy. Cell. 2018 Oct 18;175(3):766-779.e17. (PubMed)

Liao Y, Rust MJ. The Min Oscillator Defines Sites of Asymmetric Cell Division in Cyanobacteria during Stress Recovery. Cell Systems. 2018 Published online: November 7, 2018. [Epub ahead of print] (www.cell.com)

Lyon YA, Riggs D, Fornelli L, Compton PD, Julian RR. The Ups and Downs of Repeated Cleavage and Internal Fragment Production in Top-Down Proteomics. J Am Soc Mass Spectrom. 2018 Jan;29(1):150-157. (PubMed)

Maganti HB, Jrade H, Cafariello C, Manias Rothberg JL, Porter CJ, Yockell-Lelièvre J, Battaion HL, Khan ST, Howard JP, Li Y, Grzybowski AT, Sabri E, Ruthenburg AJ, Dilworth FJ, Perkins TJ, Sabloff M, Ito CY, Stanford WL. Targeting the MTF2-MDM2 axis sensitizes refractory acute myeloid leukemia to chemotherapy. Cancer Discov. 2018 Aug 16. [Epub ahead of print] (PubMed)

Malik N, Iyamu ID, Scheidt KA, Schiltz GE. Synthesis of a novel fused pyrrolodiazepine-based library with anti-cancer activity. Tetrahedron Letters, 2018. Available online 8 March 2018. [Epub ahead of print] (www.sciencedirect.com)

Manzano M, Patil A, Waldrop A, Dave SS, Behdad A, Gottwein E. Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma. Nat Commun. 2018 Aug 15;9(1):3263. (PubMed)

Martin RW, Des Soye BJ, Kwon YC, Kay J, Davis RG, Thomas PM, Majewska NI, Chen CX, Marcum RD, Weiss MG, Stoddart AE, Amiram M, Ranji Charna AK, Patel JR, Isaacs FJ, Kelleher NL, Hong SH, Jewett MC. Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids. Nat Commun. 2018 Mar 23;9(1):1203. (PubMed)

McGinnis JE, Venegas LA, Lopez H, Kay BK. A Recombinant Affinity Reagent Specific for a Phosphoepitope of Akt1. Int J Mol Sci. 2018 Oct 24;19(11). (PubMed)

Melamed RD, Rzhetsky A. Patchwork of contrasting medication cultures across the USA. Nat Commun. 2018 Oct 9;9(1):4022. (PubMed)

Miley GP, Rote JC, Silverman RB, Kelleher NL, Thomson RJ. Total Synthesis of Tambromycin Enabled by Indole C-H Functionalization. Org Lett. 2018 Mar 27. [Epub ahead of print] (PubMed)

Mukherjee S, Griffin DH, Horn JR, Rizk SS, Nocula-Lugowska M, Malmqvist M, Kim SS, Kossiakoff AA. Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins. J Biol Chem. 2018 Feb 23;293(8):2815-2828. [Epub ahead of print] (PubMed)

Mullowney MW, McClure RA, Robey MT, Kelleher NL, Thomson RJ. Nat Prod Rep. 2018 Jun 19. doi: 10.1039/c8np00013a. [Epub ahead of print] Review. (PubMed)

Nekrasova O, Harmon RM, Broussard JA, Koetsier JL, Godsel LM, Fitz GN, Gardel ML, Green KJ. Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination. Nat Commun. 2018 Mar 13;9(1):1053. (PubMed)

Nguyen HA, Su Y, Zhang JY, Antanasijevic A, Caffrey M, Schalk AM, Liu L, Rondelli D, Oh A, Mahmud DL, Bosland MC, Kajdacsy-Balla A, Peirs S, Lammens T, Mondelaers V, De Moerloose B, Goossens S, Schlicht MJ, Kabirov KK, Lyubimov AV, Merrill BJ, Saunthararajah Y, Van Vlierberghe P, Lavie A. A Novel l-Asparaginase with low l-Glutaminase Coactivity Is Highly Efficacious against Both T- and B-cell Acute Lymphoblastic Leukemias In Vivo. Cancer Res. 2018 Mar 15;78(6):1549-1560. (PubMed)

Ntai I, Fornelli L, DeHart CJ, Hutton JE, Doubleday PF, LeDuc RD, van Nispen AJ, Fellers RT, Whiteley G, Boja ES, Rodriguez H, Kelleher NL. Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4140-4145. (PubMed)

Parameswaran R, Carvalho-de-Souza JL, Jiang Y, Burke MJ, Zimmerman JF, Koehler K, Phillips AW, Yi J, Adams EJ, Bezanilla F, Tian B. Photoelectrochemical modulation of neuronal activity with free-standing coaxial silicon nanowires. Nat Nanotechnol. 2018 Feb 19. [Epub ahead of print] (PubMed)

Park YJ, Kenney GE, Schachner LF, Kelleher NL, Rosenzweig AC. Repurposed HisC Aminotransferases Complete the Biosynthesis of Some Methanobactins. Biochemistry. 2018 Apr 25. [Epub ahead of print] (PubMed)

Parkinson EI, Tryon JH, Goering AW, Ju KS, McClure RA, Kemball JD, Zhukovsky S, Labeda DP, Thomson RJ, Kelleher NL, Metcalf WW. Discovery of the tyrobetaine natural products and their biosynthetic gene cluster via metabologenomics. ACS Chem Biol. 2018 Mar 6. [Epub ahead of print] (PubMed)

Pastor PDH, Du X, Fazal S, Davies AN, Gomez CM. Targeting the CACNA1A IRES as a Treatment for Spinocerebellar Ataxia Type 6. Cerebellum. 2018 Feb;17(1):72-77. (PubMed)

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