Exploring Human Biology with Small Molecules
The 11th Annual CBC Symposium, Exploring Human Biology with Small Molecules, will be held at the Ida Noyes Hall at the University of Chicago Campus, on Friday, October 11, 2013. This full day event is organized by Sergey A. Kozmin, PhD, Professor, Department of Chemistry, The University of Chicago, Karl A. Scheidt, PhD, Associate Professor, Department of Chemistry, Northwestern University, Jie Liang, PhD, Professor, Department of Bioengineering, University of Illinois at Chicago, and Shohei Koide, PhD, Professor, Department of Biochemistry and Molecular Biology, and the CBC Scientific Director, The University of Chicago.
Attendance is free but pre-registration is required.
Online registration and poster abstract submission are now closed.
Late registrations will be accepted on site on the symposium day. However, if you have not registered online but plan to participate please email Jola Glotzer beforehand at so the CBC staff can adequately prepare for the event.
To download the symposium announcement click here.
MAPS, DIRECTIONS AND PARKING
The Ida Noyes Hall is located at 1212 East 59th Street, between South Kimbark Ave. and South Woodlawn Ave.
The CTA bus #6 (Jackson Park Express) will take you from downtown Chicago to Hyde Park. Catch the bus southbound on State Street in the Loop. Get off at 59th Street, walk under the train tracks, and continue west to Ida Noyes Hall.
You can also catch the Metra Electric commuter train at the Randolph, Van Buren, or Roosevelt station. Get off at 59th Street and walk west to Ida Noyes Hall.
From Lake Shore Drive: Exit 57th Drive. Travel west on 57th and follow the road around the Museum of Science and Industry. Continue south to the Midway Plaisance, and turn right onto the Midway. Continue westbound and turn right onto South Dorchester Ave. and then left onto East 59th Street. East 59th Street is ONE WAY street going west. Ida Noyes Hall will be on your right.
From the Dan Ryan Expressway: Exit East at Garfield Boulevard (55th Street). Continue eastbound through Washington Park to the Midway Plaisance. Continue east on the Midway, turn left onto South Dorchester Ave. and then left onto East 59th Street. East 59th Street is ONE WAY street going west. Ida Noyes Hall will be on your right.
Complimentary (free) valet service will be available to registered symposium guests. Please see map for vehicle drop off/ pick up location.
Valet parking attendants will be stationed in front of Ida Noyes Hall on 59th Street from 7:30 AM - 6:00 PM.
Street parking is very difficult at the University of Chicago Campus so taking public transportation or carpooling is strongly recommended. Limited on-street parking is available on the Midway Plaisance and on 59th Street. For the location of parking garages see UChicago Campus map.
All submitted posters have been accepted. Poster presenters: please inquire at the registration desk about your assigned poster number and space. Printed poster size should not exceed 4' (h) x 6' (w).
(updated September 9, 2013)
|8:30 AM||Registration, Continental Breakfast and Poster set-up|
|9:20 AM||Welcome and Opening Remarks by Katie Stallcup, CBC Executive Director and
Shohei Koide, CBC Scientific Director, The University of Chicago
Session I Moderator: Sergey Kozmin, The University of Chicago
|9:30 AM||Kevan M. Shokat, Howard Hughes Medical Institute, University of California, San Francisco, University of California, Berkeley
New Chemical Approaches for Treating Neurodegeneration and Cancer: Activators of the PINK1 Kinase and Inhibitors of K-Ras
|10:15 AM||Stephen J. Kron, The University of Chicago
Targeting Metabolism and Immortality in Cancer
Session II Moderator: Jie Liang, University of Illinois at Chicago
|11:15 AM||Gregory R. J. Thatcher, University of Illinois at Chicago
Beyond the Probe: From Protein Post-translational Modifications to Function
|12:00 PM||Paul J. Hergenrother, University of Illinois at Urbana-Champaign
Natural Products as an Engine for Biological Discovery
Lunch and Poster Session
Session III Moderator: Karl Scheidt, Northwestern University
|2:15 PM||Richard B. Silverman, Northwestern University
CaV1.3-Selective L-Type Calcium Channel Antagonists to Slow the Progression of Parkinson’s Disease
|3:00 PM||Virginia W. Cornish, Columbia University
Expanding the Synthetic Capabilities of Yeast
|3:45 PM||Stuart L. Schreiber, Howard Hughes Medical Institute, Broad Institute of Harvard and MIT
Human Biology, Chemical Biology & The Science of Therapeutics
To learn more about past CBC symposia, click on a respective title below. Click again to close the details panel.
Scientific leaders in the field of Epigenomics presented their research at the 10th Annual CBC Symposium: Epigenomics, which was held on Friday, October 12, 2012, at the Norris University Center on the Northwestern University Evanston campus. The scientific organizers of this event were Jason Brickner (NU), Alex Ruthenburg (UChicago), Tom Diekwisch (UIC) and Shohei Koide (UChicago CBC Scientific Director). The organizers recruited 6 outstanding speakers, 3 from the CBC universities and 3 from external institutions.
Shohei Koide, CBC Scientific Director at UChicago, gave the introductory remarks and opened the meeting. The outside speakers included Steve Henikoff, a Howard Hughes Investigator from Fred Hutchinson Cancer Research Institution in Seattle, Washington. The title of Steve’s talk was “High resolution mapping of epigenome dynamics.” Tom Misteli, a senior investigator at the National Cancer Institute, gave an eloquent talk on “Genome function beyond genome sequence.” The meeting concluded with a talk entitled “Epigenetic regulation of the stem cell fate” by Joanna Wysocka, an Assistant Professor in the Department of Chemical and Systems Biology at Stanford University. The symposium also featured talks by exceptional scientists from the three CBC universities. Jonathan Licht, a Professor of Medicine at Northwestern University, presented his research on “Disorders of histone methylation in hematological malignancy.” A talk entitled, “Reversible methylation of DNA and RNA in mammalian cells,” was given by Chuan He, a Professor of Chemistry at UChicago. UIC researcher Qun-Tian Wang, an Assistant Professor in the Department of Biological Sciences, presented her work on “Epigenetic regulation of the stem cell fate.”
A “Data Blitz” featuring short talks by selected poster presenters concluded the morning session. The selected speakers were Michael Beshiri (UIC, graduate student in Elizaveta Benevolenskaya Lab), Kara Foshay (UChicago, post-doc in Brian Lahn Lab), Gokul Gopinath (UIC, post-doc in Tom Diekwisch Lab), Takamitsu Hattori (UChicago, post-doc in Shohei Koide lab), William Light (NU, post-doc in Jason Brickner lab) and Zhaolin Zhang (NU, post-doc in Ann Harris lab).
The symposium also included an interactive poster session. Thirty posters were presented during the session and provided an excellent forum for graduate students and postdoctoral fellows to discuss their current research. The meeting was attended by 249 attendees and concluded with a networking reception at which cake was shared to celebrate the 10th Annual CBC Symposium.
Engineering Biology: From Tools to Insights
The Ninth Annual CBC Symposium, Engineering Biology: From tools to insights, took place on Friday, October 21, 2011, at the UIC Forum. David Eddington (UIC), Lonnie Shea (NU), and Joel Collier (UChicago) have collaborated to organize this scientific event. The organizational committee recruited three outstanding external keynote speakers: Christopher Chen (University of Pennsylvania), Douglas Lauffenburger (Massachusetts Institute of Technology) and Melody Swartz (Ecole Polytechnique Federale de Lausanne (EPFL), Switzerland). The symposium also featured talks by exceptional Chicago-area scientists: David Eddington (UIC), Joshua Leonard (NU) and Dorothy Sipkins (UChicago).
Brian Kay, CBC Scientific Director at UIC gave the introductory remarks and opened the meeting.
The symposium also included a poster session, which yet again proved to be extremely popular and interactive. The poster session, which provides an excellent forum for graduate students and postdoctoral fellows to present their current research, gathered 60+ posters this year! The majority of posters were presented by scientists from the three CBC universities, but the session also included posters from Illinois Institute of Technology, Children’s Memorial Hospital of Chicago, Iowa State University and the University of Illinois at Urbana-Champaign.
The symposium was attended by over 200 participants. In addition to attendees from all three CBC schools, this year's symposium attracted attendees from the University of Illinois at Urbana-Champaign, Rush University Medical Center, Baxter, Agilent Technologies, Illinois Institute of Technology, Children's Memorial Hospital of Chicago, Iowa State University, DePaul University, Argonne National Laboratory, Tel Aviv University and Wollenterprises.
The CBC is grateful for the additional sponsorship funding provided by Agilent Technologies and Baxter Healthcare Corporation. The majority of sponsorship funding comes from the Searle Funds at The Chicago Community Trust.
Protein Folding and Misfolding in Health and Disease
The 8th Annual CBC Symposium took place on October 29, 2010 within the beautiful surroundings of Ida Noyes Hall at the University of Chicago campus. This year’s symposium focused on "Protein Folding and Misfolding in Health and Disease" and aimed to address both the basic biology of protein folding in cells, and perturbations of the process, or protein misfolding, and the role that misfolding plays in aging and the development of neurodegenerative disorders (such as Huntington's, Parkinson's and Alzheimer's diseases, and Amyotrophic Lateral Sclerosis).
As one of the symposium attendees put it, this year’s symposium featured “a stellar line-up and important topics.” Indeed, the lectures were presented by four outstanding guest speakers:
Ana Maria Cuervo, MD, PhD
Professor, Departments of Developmental and Molecular Biology and of Medicine; Co-director, Einstein Institute for Aging Studies, Albert Einstein College of Medicine; Recipient of P. Benson Award in Cell Biology (2005), Keith Porter Fellow in Cell Biology (2005/8), Nathan Shock Memorial Lecture Award (2006), and Vincent Cristofalo Rising Star in Aging Award (2008)
Steven Finkbeiner, MD, PhD
Associate Director and Senior Investigator, Gladstone Institute of Neurological Disease; Director, Taube-Koret Center for Huntington’s Disease Research; Professor of Neurology and Physiology, University of California, San Francisco
Judith Frydman, PhD
Professor, Biology, School of Humanities and Sciences, Stanford University
Randal J. Kaufman, PhD
Warner-Lambert/Park-Davis Professor of Medicine; Professor, Departments of Biological Chemistry and Internal Medicine, University of Michigan; Recipient of Distinguished Investigator Award from Michigan Hemophilia Society (2000), Van Wezel Prize (2003), and an American Association for the Advancement of Science Award (2007),
and two Chicago-area based scientists:
Scott T. Brady, PhD
Professor and Head, Department of Anatomy and Cell Biology, University of Illinois at Chicago,
and a CBC Scientific Director Richard I. Morimoto, PhD
Bill and Gayle Cook Professor of Biology; Professor of Molecular Biosciences; Director, Rice Institute for Biomedical Research, Northwestern University; Recipient of American Cancer Society Faculty Research Award; Dreyfus Distinguished Young Faculty Award; NIH Merit Award; Fellow of the American Association for the Advancement of Science; Huntington Disease Society of America, Award for Excellence in Medicine.
The meeting opened with introductory remarks by Sangram (Sam) S. Sisodia, PhD, Thomas Reynolds Sr. Family Professor of Neurosciences, and Director of the Center for Molecular Neurobiology, University of Chicago.
Over 200 scientists actively participated in this year’s symposium. All three CBC universities were well-represented among the symposium attendees, who also included scientists from Rosalind Franklin University, Toyota Technological Institute at Chicago, Chicago State University, Illinois Institute of Technology, Rush University Medical Center, University of Massachusetts Medical School, among others. In addition, the symposium presented a popular poster session that this year gathered a record number of posters (28) in the history of the CBC annual symposia.
(see commentary: Folding Failures and Brain Diseases, Science Life, Nov. 10, 2010)
The Biology of Non-Coding RNAs: Old Molecules, New Actions
One of the most amazing discoveries in the last decade is the realization that non-coding RNAs perform a wide variety of cellular functions. The days are long gone when RNAs were only considered as information carriers of DNA. Today, we know RNA molecules control many cellular processes including chromatin organization, splicing, translation, and viral defense. Functional non-coding RNA molecules range from hundreds in bacteria to possibly tens of thousands in humans.
"The Biology of Non-Coding RNAs: Old Molecules, New Actions" was the topic of the Seventh Annual Chicago Biomedical Consortium Symposium held Friday, October 30, 2009 at the Feinberg Pavilion Conference Center, Northwestern Memorial Hospital in Chicago. Each year CBC annual symposia focus on a specific research area featuring outstanding guest speakers and highlighting local researchers. This year’s symposium brought together speakers who are at the forefront of non-coding RNA research:
Jennifer Doudna, PhD
Howard Hughes Investigator and Professor of Biochemistry and Molecular Biology, University of California Berkeley; Winner of 2000 Alan T. Waterman Award
Gisela Storz, PhD
Head of the Section on Environmental Gene Regulation, National Institute of Child Health and Human Development
John Rinn, PhD
Assistant professor of Pathology, Harvard Medical School
Richard Carthew, PhD
Professor of Biochemistry, Molecular Biology and Cell Biology, Northwestern University
Alexander Mankin, PhD
Professor, Center for Pharmaceutical Biotechnology, University of Illinois at Chicago Manyuan Long, PhD
Professor, Department of Ecology and Evolution, University of Chicago.
The topics ranged from regulatory and functional RNAs in bacteria to small and large non-coding RNAs in eukaryotes.
Close to 200 participants attended this year's symposium. The day also included a morning poster session and a closing reception. Nicholas Reiter from the Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, received first prize for his poster titled: Structural studies of an RNase P/tRNA ternary complex.
Frontiers in Molecular Imaging: From Promise to Practice
The Sixth Annual Chicago Biomedical Consortium Symposium, Frontiers in Molecular Imaging: From Promise to Practice, was held Friday, October 31, 2008 at the UIC Forum. CBC annual symposia feature outstanding guest speakers and also highlight local researchers, focusing on a specific subject area.
This year’s symposium included distinguished guest speakers Christopher Contag, PhD (Stanford University), winner of the Society for Molecular Imaging Achievement Award; Robert S. Balaban, PhD, Scientific Director of the National Heart, Lung, and Blood Institute intramural program; and Michael Phelps, PhD (UCLA), recipient of multiple accolades including the Enrico Fermi Presidential Award presented by President Clinton. Local researchers highlighted in the program include Thomas Meade, PhD, Northwestern University; Chin-Tu Chen, PhD, The University of Chicago; and Keith Thulborn, MD, PhD, University of Illinois at Chicago.
Approximately 200 people attended the 2008 Symposium. Along with informative presentations, opportunities for networking at this daylong event were offered during lunch and at a closing reception. Twenty-four posters prepared by researchers at Northwestern University, University of Illinois at Chicago, and The University of Chicago were presented during the poster session. Two were selected as best poster and the authors received an IPod.
Where Science Goes Next: Translation of Basic Discovery for Human Health
The Fifth Annual Chicago Biomedical Consortium Symposium, "Where Science Goes Next: Translation of Basic Discovery for Human Health", was held Friday, October 19, 2007 at the Illinois Science + Technology Park in Skokie, IL. The CBC welcomed Keynote speakers John Kessler, MD (NU); Mark Ratain, MD (UC); and Anna Barker, PhD (National Cancer Institute).
The afternoon programming included a panelist discussion, "BioScience, Industry and Academic Collaborations: Today and Tomorrow", with moderator Michael Rosen, Senior Vice President, New Business Development, Science & Technology Group, Forest City Enterprises, Inc. and panelists Norbert Riedel, PhD (Baxter), Gary Gordon, MD, PhD (Abbott), Mark Weinberg, MD (Takeda), and Michael Flavin, PhD (Advanced Life Sciences).
Infrastructures for Systems Biology
The CBC held the Fourth Annual Symposium on September 29, 2006. Speakers included:
Ken Buetow, PhD
Director, Center for Bioinformatics, and Chief of Laboratory for Population Genetics, National Cancer Institute, winner of The Editor’s Choice Award from Bio-IT World (2008);
Leroy Hood, MD, PhD
President, Institute for Systems Biology, Winner of Lasker Award and Kyoto Prize;
Kevin White, PhD
Director, Institute for Genomics and Systems Biology, University of Chicago and Argonne National Laboratory.
The all day event also included a poster session and a CBC Infrastructures Panel discussion with the Proteomics/Informatics Advisory Board.
Proteomics and Informatics
Nobel Laureate Aaron Ciechanover, PhD delivered the keynote address at a free public symposium, “Proteomics and Informatics,” on Friday, April 22, sponsored by the Chicago Biomedical Consortium.
The CBC acquired a Fourier Transform Mass Spectrometer (FTMS), the world’s most powerful tool for studying the structures of proteins and other biomolecules. The special symposium focused on how researchers can take advantage of the new technology and related analytic techniques when addressing the basic questions of proteomics (the study of proteins and their functions).
Ciechanover, who, together with two others, received the 2004 Nobel Prize in Chemistry for the discovery of a key way cells destroy unwanted proteins, spoke on “Proteomics and the Future of Medicine.” Ciechanover, Distinguished Professor at the Rappaport Family Institute for Research in the Medical Sciences at the Technion (Israel Institute of Technology), Haifa, was visiting professor at Northwestern University Feinberg School of Medicine.
Following Ciechanover’s address, Richard Carthew, PhD, professor of biochemistry, molecular biology and cell biology at Northwestern, spoke on “Proteomics and RNA Mediated Regulation of Gene Expression.” Dr. Carthew's talk was followed by Alexander Schilling, PhD, Director, Proteomic and Informatics Services Proteomic Services Facility, UIC. The event concluded with a panel discussion entitled “How the CBC Will Change Your Proteomics/Informatics Life.”
The New Biology: Technological Innovations Applied to Health and Disease
DATE: September 2, 2002
TIME: 9:00 AM - 1:00 PM
LOCATION: Adler Planetarium, Chicago, IL
The first symposium was the initial CBC organizational event which brought scientists from the three CBC institutions together in order to promote interest in planning large-scale regional initiatives.
Andrzej Joachiemiak, PhD
Director of the Advanced Photon Source, Argonne National Lab
Janet Rowley, MD
Professor of Medicine, U. Chicago; Winner of Lasker Award and National Medal of Science; 2009 Presidential Medal of Freedom
Milan Mrksich, PhD
Professor Chemistry, University of Chicago
Robert Grossman, PhD
Professor of Math and Director, Laboratory for Advanced Computing, UIC
Thomas Meade, PhD
Professor of Chemistry, Northwestern University