cbc scholars bios
Elizabeth Tarasewicz
CBC Scholar: Class of 2012
PhD Candidate, Department of Surgery, NU
Advisor: Jacqueline Jeruss
Email:
JERUSS WEBPAGE
RESEARCH INTERESTS:
TGF-β signaling has been shown to play a significant, yet paradoxical role in breast cancer progression; however, the mechanism(s) of this oncogenic switch have not been elucidated. My research is focused on how biological variants that correlate with aggressive breast cancer may mediate the switch from TGF-β directed tumor suppression to oncogenesis in breast cancer. I am also interested in patterning signaling network activity of aggressive breast cancer cell types using a novel transcription factor array and following changes in pathway activity upon treatment with targeted agents. Ultimately, I hope my work will provide insight into how such information can be used to define patients populations that would benefit from specific therapeutic strategies.
PUBLICATIONS:
Prasad K, Tarasewicz E, Strickland PA, O'Neill M, Mitchell SN, Merchant K, Tep S, Hilton K, Datwani A, Buttini M, Mueller-Steiner S, Richfield EK. Biochemical and morphological consequences of human α-synuclein expression in a mouse α-synuclein null background. Eur J Neurosci. 2011 Feb;33(4):642-56. doi: 10.1111/j.1460-9568.2010.07558.x. (PubMed)
Prasad K, Tarasewicz E, Mathew J, Strickland PA, Buckley B, Richardson JR, Richfield EK. Toxicokinetics and toxicodynamics of paraquat accumulation in mouse brain. Exp Neurol. 2009 Feb;215(2):358-67. (PubMed)
AWARDS,:
- NIH NRSA Fellowship 2012-2015
- Chicago Biomedical Consortium Scholar 2012
- Carcinogenesis Training Grant 2011-2012
- Biotechnology Training Grant Cluster 2010-2011
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