CBC-Funded Publications 2014

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Aggarwal C, Jimenez JC, Nanavati D, Federle MJ. Multiple Length Peptide-Pheromone Variants Produced by Streptococcus pyogenes Directly Bind Rgg Proteins to Confer Transcriptional Regulation. J Biol Chem. 2014 Aug 8;289(32):22427-36. (PubMed)

Albright JC, Goering AW, Doroghazi JR, Metcalf WW, Kelleher NL. Strain-specific proteogenomics accelerates the discovery of natural products via their biosynthetic pathways. J Ind Microbiol Biotechnol. 2014 Feb;41(2):451-9. (PubMed)

Alhasan AH, Patel PC, Choi CH, Mirkin CA. Exosome encased spherical nucleic acid gold nanoparticle conjugates as potent microRNA regulation agents. Small. 2014 Jan 15;10(1):186-92. (PubMed)

Alkorta-Aranburu G, Carmody D, Cheng YW, Nelakuditi V, Ma L, Dickens JT, Das S, Greeley SA, del Gaudio D. Phenotypic heterogeneity in monogenic diabetes: the clinical and diagnostic utility of a gene panel-based next-generation sequencing approach. Mol Genet Metab. 2014 Dec;113(4):315-20. (PubMed)

Antanasijevic A, Basu A, Bowlin TL, Mishra RK, Rong L, Caffrey M. Mutagenesis Studies of the H5 Influenza Hemagglutinin Stem Loop Region. J Biol Chem. 2014 Aug 8;289(32):22237-45. (PubMed)

Antanasijevic A, Ramirez B, Caffrey M. Comparison of the sensitivities of WaterLOGSY and saturation transfer difference NMR experiments. J Biomol NMR. 2014 Sep;60(1):37-44. (PubMed)

Aprison EZ, Ruvinsky I. Balanced trade-offs between alternative strategies shape the response of C. elegans reproduction to chronic heat stress. PLoS One. 2014 Aug 28;9(8):e105513. eCollection 2014. (PubMed)

Arthur RK, Ma L, Slattery M, Spokony RF, Ostapenko A, Nègre N, White KP. Evolution of H3K27me3-marked chromatin is linked to gene expression evolution and to patterns of gene duplication and diversification. Genome Res. 2014 Jul;24(7):1115-24. (PubMed)

Asada K, Canestrari E, Fu X, Li Z, Makowski E, Wu YC, Mito JK, Kirsch DG, Baraban J, Paroo Z. Rescuing dicer Defects via Inhibition of an Anti-dicing Nuclease. Cell Rep. 2014 Nov 6;9(4):1471-1481. (PubMed)

Atkinson IC, Claiborne TC, Thulborn KR. Feasibility of 39-potassium MR imaging of a human brain at 9.4 Tesla. Magn Reson Med. 2014 May;71(5):1819-25. (PubMed)

Auyeung E, Li TI, Senesi AJ, Schmucker AL, Pals BC, de la Cruz MO, Mirkin CA. DNA-mediated nanoparticle crystallization into Wulff polyhedra. Nature. 2014 Jan 2;505(7481):73-7. (PubMed)

Bailey LJ, Sheehy KM, Hoey RJ, Schaefer ZP, Ura M, Kossiakoff AA. Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments. J Immunol Methods. 2014 Dec 15;415:24-30. (PubMed)

Banga RJ, Chernyak N, Narayan SP, Nguyen ST, Mirkin CA. Liposomal spherical nucleic acids. J Am Chem Soc. 2014 Jul 16;136(28):9866-9. (PubMed)

Barnaby SN, Lee A, Mirkin CA. Probing the inherent stability of siRNA immobilized on nanoparticle constructs. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9739-44. (PubMed)

Basu A, Antanasijevic A, Wang M, Li B, Mills DM, Ames JA, Nash PJ, Williams JD, Peet NP, Moir DT, Prichard MN, Keith KA, Barnard DL, Caffrey M, Rong L, Bowlin TL. New small molecule entry inhibitors targeting hemagglutinin-mediated influenza a virus fusion. J Virol. 2014 Feb;88(3):1447-60. (PubMed)

Baumgarten SC, Convissar SM, Fierro MA, Winston NJ, Scoccia B, Stocco C. IGF1R signaling is necessary for FSH-induced activation of AKT and differentiation of human cumulus granulosa cells. J Clin Endocrinol Metab. 2014 Aug;99(8):2995-3004. (PubMed)

Bian S, Zieba SB, Morris W, Han X, Richter DC, Brown KA, Mirkin CA, Braunschweig AB. Beam Pen Lithography as a New Tool for Spatially Controlled Photochemistry, and its Utilization in the Synthesis of Multivalent Glycan Arrays. Chem. Sci. 2014, 5, 2023-2030. (rcs.org)

Black KC, Sileika TS, Yi J, Zhang R, Rivera JG, Messersmith PB. Bacterial killing by light-triggered release of silver from biomimetic metal nanorods. Small. 2014 Jan 15;10(1):169-78. (PubMed)

Blair DR, Wang K, Nestorov S, Evans JA, Rzhetsky A. Quantifying the impact and extent of undocumented biomedical synonymy. PLoS Comput Biol. 2014 Sep 25;10(9):e1003799. eCollection 2014 Sep. (PubMed)

Boehler RM, Kuo R, Shin S, Goodman AG, Pilecki MA, Leonard JN, Shea LD. Lentivirus delivery of IL-10 to promote and sustain macrophage polarization towards an anti-inflammatory phenotype. Biotechnol Bioeng. 2014 Jun;111(6):1210-21. (PubMed)

Boisclair Lachance JF, Peláez N, Cassidy JJ, Webber JL, Rebay I, Carthew RW. A comparative study of Pointed and Yan expression reveals new complexity to the transcriptional networks downstream of receptor tyrosine kinase signaling. Dev Biol. 2014 Jan 15;385(2):263-78. (PubMed)

Boyle AP, Araya CL, Brdlik C, Cayting P, Cheng C, Cheng Y, Gardner K, Hillier LW, Janette J, Jiang L, Kasper D, Kawli T, Kheradpour P, Kundaje A, Li JJ, Ma L, Niu W, Rehm EJ, Rozowsky J, Slattery M, Spokony R, Terrell R, Vafeados D, Wang D, Weisdepp P, Wu YC, Xie D, Yan KK, Feingold EA, Good PJ, Pazin MJ, Huang H, Bickel PJ, Brenner SE, Reinke V, Waterston RH, Gerstein M, White KP, Kellis M, Snyder M. Comparative analysis of regulatory information and circuits across distant species. Nature. 2014 Aug 28;512(7515):453-6. (PubMed)

Brady PB, Oda S, Yamamoto H. Stereodivergent approach to the avermectins based on “super silyl” directed aldol reactions. Org Lett. 2014 Aug 1;16(15):3864-7. (PubMed)

Brehme M, Voisine C, Rolland T, Wachi S, Soper JH, Zhu Y, Orton K, Villella A, Garza D, Vidal M, Ge H, Morimoto RI. A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease. Cell Rep. 2014 Nov 6;9(3):1135-50. (PubMed)

Briguglio JS, Turkewitz AP. Tetrahymena thermophila: A divergent perspective on membrane traffic. J Exp Zool B Mol Dev Evol. 2014 Nov;322(7):500-16. (PubMed)

Bryant J, Hlavaty KA, Zhang X, Yap WT, Zhanga L, Shea LD, Luo X. Nanoparticle delivery of donor antigens for transplant tolerance in allogeneic islet transplantation. Biomaterials. 2014 Oct;35(31):8887-94. (PubMed)

Cabezas MD, Eichelsdoerfer DJ, Brown KA, Mrksich M, Mirkin CA. Combinatorial screening of mesenchymal stem cell adhesion and differentiation using polymer pen lithography. Methods Cell Biol. 2014;119:261-76. (PubMed)

Cannon JR, Cammarata MB, Robotham SA, Cotham VC, Shaw JB, Fellers RT, Early BP, Thomas PM, Kelleher NL, Brodbelt JS. Ultraviolet photodissociation for characterization of whole proteins on a chromatographic time scale. Anal Chem. 2014 Feb 18;86(4):2185-92. (PubMed)

Carmody D, Bell CD, Hwang JL, Dickens JT, Sima DI, Felipe DL, Zimmer CA, Davis AO, Kotlyarevska K, Naylor RN, Philipson LH, Greeley SA. Sulfonylurea treatment before genetic testing in neonatal diabetes: pros and cons. J Clin Endocrinol Metab. 2014 Dec;99(12):E2709-14. (PubMed)

Carney CE, Macrenaris KW, Mastarone DJ, Kasjanski DR, Hung AH, Meade TJ. Cell Labeling via Membrane-Anchored Lipophilic MR Contrast Agents. Bioconjug Chem. 2014 May 21;25(5):945-54. (PubMed)

Catherman AD, Skinner OS, Kelleher NL. Top Down Proteomics: Facts and Perspectives. Biochem Biophys Res Commun. 2014 Mar 21;445(4):683-693. (PubMed)

Chanut-Delalande H, Hashimoto Y, Pelissier-Monier A, Spokony R, Dib A, Kondo T, Bohère J, Niimi K, Latapie Y, Inagaki S, Dubois L, Valenti P, Polesello C, Kobayashi S, Moussian B, White KP, Plaza S, Kageyama Y, Payre F. Pri peptides are mediators of ecdysone for the temporal control of development. Nat Cell Biol. 2014 Nov;16(11):1035-44. (PubMed)

Chen C, Zhang C, Cheng L, Reilly JL, Bishop JR, Sweeney JA, Chen HY, Gershon ES, Liu C. Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia. Bipolar Disord. 2014 Dec;16(8):790-9. (PubMed)

Chen S, Deng J, Yuan Y, Flachenecker C, Mak R, Hornberger B, Jin Q, Shu D, Lai B, Maser J, Roehrig C, Paunesku T, Gleber SC, Vine DJ, Finney L, VonOsinski J, Bolbat M, Spink I, Chen Z, Steele J, Trapp D, Irwin J, Feser M, Snyder E, Brister K, Jacobsen C, Woloschak G, Vogt S. The Bionanoprobe: hard X-ray fluorescence nanoprobe with cryogenic capabilities. J Synchrotron Radiat. 2014 Jan;21(Pt 1):66-75. (PubMed)

Chen Z, Grzybowski AT, Ruthenburg AJ. Traceless semisynthesis of a set of histone 3 species bearing specific lysine methylation marks. Chembiochem. 2014 Sep 22;15(14):2071-5. (PubMed)

Cheng Y, Dai Q, Morshed RA, Fan X, Wegscheid ML, Wainwright DA, Han Y, Zhang L, Auffinger B, Tobias AL, Rincón E, Thaci B, Ahmed AU, Warnke PC, He C, Lesniak MS. Blood-brain barrier permeable gold nanoparticles: an efficient delivery platform for enhanced malignant glioma therapy and imaging. Small. 2014 Dec 29;10(24):5137-50. (PubMed)

Cho BK, Koo YD, Kim K, Kang MJ, Lee YY, Kim Y, Park KS, Kim KP, Yi EC. Determination of selected reaction monitoring peptide transitions via multiplexed product-ion scan modes. Rapid Commun. Mass Spectrom. 2014 28: 773–780. (wiley.com)

Chung E, Pineda F, Nord K, Karczmar, Lee SK, Tirrell M. Fibrin-Targeting, Peptide Amphiphile Micelles as Contrast Agents for Molecular MRI. J Cell Sci Ther. 2014 5:181. (omicsonline.org)

Cinelli MA, Li H, Chreifi G, Martásek P, Roman LJ, Poulos TL, Silverman RB. Simplified 2-aminoquinoline-based scaffold for potent and selective neuronal nitric oxide synthase inhibition. J Med Chem. 2014 Feb 27;57(4):1513-30. (PubMed)

Cocco S, Marko JF, Monasson R. Stochastic ratchet mechanisms for replacement of proteins bound to DNA. Phys Rev Lett. 2014 Jun 13;112(23):238101. (PubMed)

Cone JJ, McCutcheon JE, Roitman MF. Ghrelin Acts as an Interface between Physiological State and Phasic Dopamine Signaling. J Neurosci. 2014 Apr 2;34(14):4905-13. (PubMed)

Dam DH, Culver KS, Odom TW. Grafting aptamers onto gold nanostars increases in vitro efficacy in a wide range of cancer cell types. Mol Pharm. 2014 Feb 3;11(2):580-7. (PubMed)

Dam DH, Lee RC, Odom TW. Improved in vitro efficacy of gold nanoconstructs by increased loading of G-quadruplex aptamer. Nano Lett. 2014 May 14;14(5):2843-8. (PubMed)

Dang X, Scotcher J, Wu S, Chu RK, Tolić N, Ntai I, Thomas PM, Fellers RT, Early BP, Zheng Y, Durbin KR, Leduc RD, Wolff JJ, Thompson CJ, Pan J, Han J, Shaw JB, Salisbury JP, Easterling M, Borchers CH, Brodbelt JS, Agar JN, Paša-Tolić L, Kelleher NL, Young NL. The First Pilot Project of the Consortium for Top Down Proteomics: A Status Report. Proteomics. 2014 May;14(10):1130-40. (PubMed)

DasGupta B, Dundas J, Liang J. Algorithmic Methodologies for Discovery of Non-sequential Protein Structure Similarities.  In: Algorithmic and Artificial Intelligence Methods for Protein Bioiriformatics. First Edition. Edited by Yi Pan, Jianxin Wang, Min Li. © 2014 John Wiley & Sons, Inc. Published 2014 by John Wiley & Sons, Inc. pp. 299-316. (ieee.org)

Daugherty RL, Serebryannyy L, Yemelyanov A, Flozak AS, Yu HJ, Kosak ST, deLanerolle P, Gottardi CJ. α-Catenin is an inhibitor of transcription. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5260-5. (PubMed)

DeLaMarre MF, Shippy SA. Development of a simplified microfluidic injector for analysis of droplet content via capillary electrophoresis. Anal Chem. 2014 Oct 21;86(20):10193-200. (PubMed)

Deng X, Liang H, Ulanovskaya OA, Ji Q, Zhou T, Sun F, Lu Z, Hutchison AL, Lan L, Wu M, Cravatt BF, He C. Steady-state hydrogen peroxide induces glycolysis in Staphylococcus aureus and Pseudomonas aeruginosa. J Bacteriol. 2014 Jul;196(14):2499-513. (PubMed)

DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium; Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium; South Asian Type 2 Diabetes (SAT2D) Consortium; Mexican American Type 2 Diabetes (MAT2D) Consortium; Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 2014 Mar;46(3):234-44. (PubMed)

Dombeck D, Tank D. Two-photon imaging of neural activity in awake mobile mice. Cold Spring Harb Protoc. 2014 Jul 1;2014(7):726-36. (PubMed)

Doroghazi JR, Albright JC, Goering AW, Ju KS, Haines RR, Tchalukov KA, Labeda DP, Kelleher NL, Metcalf WW. A roadmap for natural product discovery based on large-scale genomics and metabolomics. Nat Chem Biol. 2014 Nov;10(11):963-8. (PubMed)

Doshi-Velez F, Ge Y, Kohane I. Comorbidity clusters in autism spectrum disorders: an electronic health record time-series analysis. Pediatrics. 2014 Jan;133(1):e54-63. (PubMed)

Dose M, Emmanuel AO, Chaumeil J, Zhang J, Sun T, Germar K, Aghajani K, Davis EM, Keerthivasan S, Bredemeyer AL, Sleckman BP, Rosen ST, Skok JA, Le Beau MM, Georgopoulos K, Gounari F. β-Catenin induces T-cell transformation by promoting genomic instability. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):391-6. (PubMed)

Dreixler JC, Poston JN, Balyasnikova I, Shaikh AR, Tupper KY, Conway S, Boddapati V, Marcet MM, Lesniak MS, Roth S. Delayed Administration of Bone Marrow Mesenchymal Stem Cell Conditioned Media Significantly Improves Outcome after Retinal Ischemia in Rats. Invest Ophthalmol Vis Sci. 2014 Apr 3;55(6):3785-96. (PubMed)

Duncan MT, Shin S, Wu JJ, Mays Z, Weng S, Bagheri N, Miller WM, Shea LD. Dynamic transcription factor activity profiles reveal key regulatory interactions during megakaryocytic and erythroid differentiation. Biotechnol Bioeng. 2014 Oct;111(10):2082-94. (PubMed)

Durbin KR, Fellers RT, Ntai I, Kelleher NL, Compton PD. Autopilot: an online data acquisition control system for the enhanced high-throughput characterization of intact proteins. Anal Chem. 2014 Feb 4;86(3):1485-92. (PubMed)

Dyson MT, Roqueiro D, Monsivais D, Ercan CM, Pavone ME, Brooks DC, Kakinuma T, Ono M, Jafari N, Dai Y, Bulun SE. Genome-wide DNA methylation analysis predicts an epigenetic switch for GATA factor expression in endometriosis. PLoS Genet. 2014 Mar 6;10(3):e1004158. eCollection 2014 Mar. (PubMed)

Ebel ME, Kansas GS. Defining the functional boundaries of the murine α1,3 fucosyltransferase Fut7 reveals a remarkably compact locus. J Biol Chem. 2014 Mar 7;289(10):6341-9. (PubMed)

Eckermann AL, Mastarone DJ, Meade TJ. Chemical Strategies for the Development of Multimodal Imaging Probes Using Nanoparticles. In: The Chemistry of Molecular Imaging. Long N, Wong WT, ed. Wiley Publishing. 2014 Dec 15. ISBN: 978-1-118-09327-6 (wiley.com)

Fica SM, Mefford MA, Piccirilli JA, Staley JP. Evidence for a group II intron-like catalytic triplex in the spliceosome. Nat Struct Mol Biol. 2014 May;21(5):464-71. (PubMed)

Filippova EV, Luan CH, Dunne SF, Kiryukhina O, Minasov G, Shuvalova L, Anderson WF. Structural characterization of a hypothetical protein: a potential agent involved in trimethylamine metabolism in Catenulispora acidiphila. J Struct Funct Genomics. 2014 Mar;15(1):33-40. (PubMed)

Gamazon ER, Cox NJ, Davis LK. Structural architecture of SNP effects on complex traits. Am J Hum Genet. 2014 Nov 6;95(5):477-89. (PubMed)

Ghosh AK, Schiltz GE, Rusere LN, Osswald HL, Walters DE, Amano M, Mitsuya H. Design and synthesis of potent macrocyclic HIV-1 protease inhibitors involving P1-P2 ligands. Org Biomol Chem. 2014 Sep 21;12(35):6842-54. (PubMed)

Gottlieb A, Altman RB. Integrating systems biology sources illuminates drug action. Clin Pharmacol Ther. 2014 Jun;95(6):663-9. (PubMed)

Gómez-Mendoza DP, Junqueira M, do Vale LH, Domont GB, Ferreira Filho EX, Sousa MV, Ricart CA. Secretomic Survey of Trichoderma harzianum Grown on Plant Biomass Substrates. J Proteome Res. 2014 Apr 4;13(4):1810-22. (PubMed)

Grennan KS, Chen C, Gershon ES, Liu C. Molecular network analysis enhances understanding of the biology of mental disorders. Bioessays. 2014 Jun;36(6):606-16. (PubMed)

Gürsoy G, Xu Y, Kenter AL, Liang J. Spatial confinement is a major determinant of the folding landscape of human chromosomes. Nucleic Acids Res. 2014;42(13):8223-30. (PubMed)

Gürsoy G, Xu Y, Liang J. Computational Predictions of Structures of Multichromosomes of Budding Yeast. Conf Proc IEEE Eng Med Biol Soc. 2014. Issue date: Aug 26-30, 2014. (ieee.org)

Halo TL, McMahon KM, Angeloni NL, Xu Y, Wang W, Chinen AB, Malin D, Strekalova E, Cryns VL, Cheng C, Mirkin CA, Thaxton CS. NanoFlares for the detection, isolation, and culture of live tumor cells from human blood. Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17104-9. (PubMed)

Hart AB, Gamazon ER, Engelhardt BE, Sklar P, Kähler AK, Hultman CM, Sullivan PF, Neale BM, Faraone SV; Psychiatric Genomics Consortium: ADHD Subgroup, de Wit H, Cox NJ, Palmer AA. Genetic variation associated with euphorigenic effects of d-amphetamine is associated with diminished risk for schizophrenia and attention deficit hyperactivity disorder. Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):5968-73. (PubMed)

Hause RJ, Stark AL, Antao NN, Gorsic LK, Chung SH, Brown CD, Wong SS, Gill DF, Myers JL, To LA, White KP, Dolan ME, Jones RB. Identification and validation of genetic variants that influence transcription factor and cell signaling protein levels. Am J Hum Genet. 2014 Aug 7;95(2):194-208. (PubMed)

He BZ, Ludwig MZ, Dickerson DA, Barse L, Arun B, Vilhjálmsson BJ, Jiang P, Park SY, Tamarina NA, Selleck SB, Wittkopp PJ, Bell GI, Kreitman M. Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin. Genetics. 2014 Feb;196(2):557-67. (PubMed)

Heath AP, Greenway M, Powell R, Spring J, Suarez R, Hanley D, Bandlamudi C, McNerney ME, White KP, Grossman RL. Bionimbus: a cloud for managing, analyzing and sharing large genomics datasets. J Am Med Inform Assoc. 2014 Nov;21(6):969-75. (PubMed)

Heffern MC, Matosziuk LM, Meade TJ. Lanthanide probes for bioresponsive imaging. Chem Rev. 2014 Apr 23;114(8):4496-539. (PubMed)

Heffern MC, Velasco PT, Matosziuk LM, Coomes JL, Karras C, Ratner MA, Klein WL, Eckermann AL, Meade TJ. Modulation of amyloid-β aggregation by histidine-coordinating Cobalt(III) Schiff base complexes. Chembiochem. 2014 Jul 21;15(11):1584-9. (PubMed)

Heys JG, Rangarajan KV, Dombeck DA. The Functional Micro-organization of Grid Cells Revealed by Cellular-Resolution Imaging. Neuron. 2014 Dec 3;84(5):1079-90. (PubMed)

Hlavaty KA, Gibly RF, Zhang X, Rives CB, Graham JG, Lowe WL Jr, Luo X, Shea LD. Enhancing Human Islet Transplantation by Localized Release of Trophic Factors From PLG Scaffolds. Am J Transplant. 2014 Jul;14(7):1523-32. (PubMed)

Hon GC, Song CX, Du T, Jin F, Selvaraj S, Lee AY, Yen CA, Ye Z, Mao SQ, Wang BA, Kuan S, Edsall LE, Zhao BS, Xu GL, He C, Ren B. 5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation. Mol Cell. 2014 Oct 23;56(2):286-97. (PubMed)

Hong SH, Ntai I, Haimovich AD, Kelleher NL, Isaacs FJ, Jewett MC. Cell-free Protein Synthesis from a Release Factor 1 Deficient Escherichia coli Activates Efficient and Multiple Site-specific Nonstandard Amino Acid Incorporation. ACS Synth Biol. 2014 Jun 20;3(6):398-409. (PubMed)

Hong SH, Kwon YC, Jewett MC. Non-standard amino acid incorporation into proteins using Escherichia coli cell-free protein synthesis. Front. Chem. 2014 Jun 10;2:34. (PubMed)

Hong YP, Gleber SC, O’Halloran TV, Que EL, Bleher R, Vogt S, Woodruff TK, Jacobsen C. Alignment of low-dose X-ray fluorescence tomography images using differential phase contrast. J Synchrotron Radiat. 2014 Jan;21(Pt 1):229-34. (PubMed)

Huang SH, LePendu P, Iyer SV, Tai-Seale M, Carrell D, Shah NH. Toward personalizing treatment for depression: predicting diagnosis and severity. J Am Med Inform Assoc. 2014 Nov-Dec;21(6):1069-75. (PubMed)

Hudalla GA, Sun T, Gasiorowski JZ, Han H, Tian YF, Chong AS, Collier JH. Gradated assembly of multiple proteins into supramolecular nanomaterials. Nat Mater. 2014 Aug;13(8):829-36.(PubMed)

Hung AH, Holbrook RJ, Rotz MW, Glasscock CJ, Mansukhani ND, MacRenaris KW, Manus LM, Duch MC, Dam KT, Hersam MC, Meade TJ. Graphene Oxide Enhances Cellular Delivery of Hydrophilic Small Molecules by Co-incubation. ACS Nano. 2014 Oct 28;8(10):10168-77. (PubMed)

Hunter Z, McCarthy DP, Yap WT, Harp CT, Getts DR, Shea LD, Miller SD. A biodegradable nanoparticle platform for the induction of antigen-specific immune tolerance for treatment of autoimmune disease. ACS Nano. 2014 Mar 25;8(3):2148-60. (PubMed)

Hurtado S, Kim Guisbert KS, Sontheimer EJ. SPO24 Is a Transcriptionally Dynamic, Small ORF-Encoding Locus Required for Efficient Sporulation in Saccharomyces cerevisiae. PLoS One. 2014 Aug 15;9(8):e105058. eCollection 2014. (PubMed)

Hwang KB, Lee IH, Park JH, Hambuch T, Choe Y, Kim M, Lee K, Song T, Neu MB, Gupta N, Kohane IS, Green RC, Kong SW. Reducing false-positive incidental findings with ensemble genotyping and logistic regression based variant filtering methods. Hum Mutat. 2014 Aug;35(8):936-44. (PubMed)

Jacobs AC, Thompson MG, Gebhardt M, Corey BW, Yildirim S, Shuman HA, Zurawski DV. Genetic Manipulation of Acinetobacter baumannii. Curr Protoc Microbiol. 2014 Nov 3;35:6G.2.1-6G.2.11. (PubMed)

Jaiswal MK, De M, Chou SS, Vasavada S, Bleher R, Prasad PV, Bahadur D, Dravid VP. Thermoresponsive magnetic hydrogels as theranostic nanoconstructs. ACS Appl Mater Interfaces. 2014 May 14;6(9):6237-47. (PubMed)

Jimenez-Morales D, Adamian L, Shi D, Liang J. Lysine carboxylation: unveiling a spontaneous post-translational modification. Acta Cryst. 2014 Jan;70(Pt 1):48-57. (PubMed)

Jing Q, Li H, Roman LJ, Martásek P, Poulos TL, Silverman RB. An Accessible Chiral Linker to Enhance Potency and Selectivity of Neuronal Nitric Oxide Synthase Inhibitors. ACS Med Chem Lett. 2014 Jan 9;5(1):56-60. (PubMed)

Kang Y, Jelenska J, Cecchini NM, Li Y, Lee MW, Kovar DR, Greenberg JT. HopW1 from Pseudomonas syringae Disrupts the Actin Cytoskeleton to Promote Virulence in Arabidopsis. PLoS Pathog. 2014 Jun 26;10(6):e1004232. (PubMed)

Kathman SG, Xu Z, Statsyuk AV. A fragment-based method to discover irreversible covalent inhibitors of cysteine proteases. J Med Chem. 2014 Jun 12;57(11):4969-74. (PubMed)

Kelleher NL, Thomas PM, Ntai I, Compton PD, LeDuc RD. Deep and quantitative top-down proteomics in clinical and translational research. Expert Rev Proteomics. 2014 Oct 28:1-3. (PubMed)

Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos JA, Weng Z, White KP, Hardison RC. Defining functional DNA elements in the human genome. Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6131-8. (PubMed)

Kennedy BK, Berger SL, Brunet A, Campisi J, Cuervo AM, Epel ES, Franceschi C, Lithgow GJ, Morimoto RI, Pessin JE, Rando TA, Richardson A, Schadt EE, Wyss-Coray T, Sierra F. Geroscience: linking aging to chronic disease. Cell. 2014 Nov 6;159(4):709-13. (PubMed)

Khaja F, Kuzmis A, Onyuksel H. CTGF siRNA-Nanomedicine; A Potential Treatment for Renal Fibrosis, 41st Annual CRS conference proceedings. 2014. (controlledreleasesociety.org)

Kuhn ML, Zemaitaitis B, Hu LI, Sahu A, Sorensen D, Minasov G, Lima BP, Scholle M, Mrksich M, Anderson WF, Gibson BW, Schilling B, Wolfe AJ. Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation. PLoS One. 2014 Apr 22;9(4):e94816. (PubMed)

Kim DH, Park MJ, Gwon GH, Silkov A, Xu ZY, Yang EC, Song S, Song K, Kim Y, Yoon HS, Honig B, Cho W, Cho Y, Hwang I. An ankyrin repeat domain of AKR2 drives chloroplast targeting through coincident binding of two chloroplast lipids. Dev Cell. 2014 Sep 8;30(5):598-609. (PubMed)

Kim HJ, Zhang K, Moore L, Ho D. Diamond nanogel-embedded contact lenses mediate lysozyme-dependent therapeutic release. ACS Nano. 2014 Mar 25;8(3):2998-3005. (PubMed)

King CR, Nicolae DL. GWAS to Sequencing: Divergence in Study Design and Analysis. Genes (Basel). 2014 May 28;5(2):460-76. (PubMed)

Kong BY, Duncan FE, Que EL, Kim AM, O’Halloran TV, Woodruff TK. Maternally-derived zinc transporters ZIP6 and ZIP10 drive the mammalian oocyte-to-egg transition. Mol Hum Reprod. 2014 Nov;20(11):1077-89. (PubMed)

Kong SW, Sahin M, Collins CD, Wertz MH, Campbell MG, Leech JD, Krueger D, Bear MF, Kunkel LM, Kohane IS. Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis. Mol Autism. 2014 Feb 24;5(1):16. (PubMed)

Koranda JL, Cone JJ, McGehee DS, Roitman MF, Beeler JA, Zhuang X. Nicotinic Receptors Regulate the Dynamic Range of Dopamine Release In Vivo. J Neurophysiol. 2014 Jan;111(1):103-11. (PubMed)

Krishna SN, Luan CH, Clutter MR, Mishra RM, Scheidt KA, Anderson WF, Bergan RC. A high-throughput screening platform for the identification of small molecule inhibitors of MAP2K4. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 5394. (cancerres.aacrjournals.org)

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