CBC-Funded Publications 2012

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2012

Acharya P, Negre N, Johnston J, Wei Y, White KP, Henry RW, Arnosti DN. Evidence for autoregulation and cell signaling pathway regulation from genome-wide binding of the Drosophila retinoblastoma protein. G3 (Bethesda). 2012 Nov;2(11):1459-72. (PubMed)

Aghajani K, Keerthivasan S, Yu Y, Gounari F. Generation of CD4CreER(T2) transgenic mice to study development of peripheral CD4-T-cells. Genesis. 2012 Dec;50(12):908-13. (PubMed)

Ahlf DR, Compton PD, Tran JC, Early BP, Thomas PM, Kelleher NL. Evaluation of the Compact High-Field Orbitrap for Top-Down Proteomics of Human Cells. J Proteome Res. 2012 Aug 3;11(8):4308-14. (PubMed)

Alhasan AH, Kim DY, Daniel WL, Watson E, Meeks JJ, Thaxton CS, Mirkin CA. Scanometric MicroRNA Array Profiling of Prostate Cancer Markers Using Spherical Nucleic Acid-Gold Nanoparticle Conjugates. Anal Chem. 2012 May 1;84(9):4153-60. (PubMed)

Ament SA, Wang Y, Chen CC, Blatti CA, Hong F, Liang ZS, Negre N, White KP, Rodriguez-Zas SL, Mizzen CA, Sinha S, Zhong S, Robinson GE. The transcription factor ultraspiracle influences honey bee social behavior and behavior-related gene expression. PLoS Genet. 2012 Mar;8(3):e1002596. (PubMed)

Arora HC, Jensen MP, Yuan Y, Wu A, Vogt S, Paunesku T, Woloschak GE. Nanocarriers enhance Doxorubicin uptake in drug-resistant ovarian cancer cells. Cancer Res. 2012 Feb 1;72(3):769-78. (PubMed)

Arslan SY, Son KN, Lipton HL. The anti-apoptotic Mcl-1 protein controls the type of cell death in Theiler’s virus-infected BHK-21 cells. J Virol. 2012 Feb;86(4):1922-9. (PubMed)

Atkinson IC, Lu A, Thulborn KR. Preserving the accuracy and resolution of the sodium bioscale from quantitative sodium MRI during intrasubject alignment across longitudinal studies. Magn Reson Med. 2012 Sep;68(3):751-61. (PubMed)

Atkinson IC, Lu A, Thulborn KR. Quantitative Metabolic MR Imaging of Human Brain Using 17O and 23Na. In: Encyclopedia of Magnetic Resonance. Eds. R. K. Harris and R. E. Wasylishen, John Wiley. 2012. (Wiley Online Library)

Auyeung E, Macfarlane RJ, Choi CH, Cutler JI, Mirkin CA. Transitioning DNA-engineered nanoparticle superlattices from solution to the solid state. Adv Mater. 2012 Oct 2;24(38):5181-6. (PubMed)

Avner BS, Shioura KM, Scruggs SB, Grachoff M, Geenen DL, Helseth DL Jr, Farjah M, Goldspink PH, Solaro JR. Myocardial infarction in mice alters sarcomeric function via post-translational protein modification. Mol Cell Biochem. 2012 Apr;363(1-2):203-15. (PubMed)

Bai H, Kath JE, Zörgiebel FM, Sun M, Ghosh P, Hatfull GF, Grindley ND, Marko JF. Remote control of DNA-acting enzymes by varying the Brownian dynamics of a distant DNA end. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16546-51. (PubMed)

Ban L, Pettit N, Li L, Stuparu AD, Cai L, Chen W, Guan W, Han W, Wang PG, Mrksich M. Discovery of glycosyltransferases using carbohydrate arrays and mass spectrometry. Nat Chem Biol. 2012 Sep;8(9):769-73. (PubMed)

Barrière A, Gordon KL, Ruvinsky I. Coevolution within and between regulatory loci can preserve promoter function despite evolutionary rate acceleration. PLoS Genet. 2012 Sep;8(9):e1002961. (PubMed)

Bass J. Circadian topology of metabolism. Nature. 2012 Nov 15;491(7424):348-56. (PubMed)

Bass J. Drug discovery: Time in a bottle. (Invited Commentary). Nature. 2012 May 2;485(7396):45-6. (PubMed)

Beaumont KG, Mrksich M. The Mechanostability of Isolated Focal Adhesions Is Strongly Dependent on pH. Chem Biol. 2012 Jun 22;19(6):711-20. (PubMed)

Becker AM, Michael DG, Satpathy AT, Sciammas R, Singh H, Bhattacharya D. IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors. Blood. 2012 Mar 1;119(9):2003-12. (PubMed)

Bernhardt ML, Kong BY, Kim AM, O’Halloran TV, Woodruff TK. A zinc-dependent mechanism regulates meiotic progression in mammalian oocytes. Biol Reprod. 2012 Apr 19;86(4):114. (PubMed)

Bond AM, Bhalala OG, Kessler JA. The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation. Dev Neurobiol. 2012 Jul;72(7):1068-84. Review. (PubMed)

Brady PB, Yamamoto H. Rapid and stereochemically flexible synthesis of polypropionates: super-silyl-governed aldol cascades. Angew Chem Int Ed Engl. 2012 Feb 20;51(8):1942-6. (PubMed)

Brugarolas P, Movahedzadeh F, Wang Y, Zhang N, Bartek IL, Gao YN, Voskuil MI, Franzblau SG, He C. The oxidation-sensing regulator (MosR) is a new redox dependent transcription factor in Mycobacterium tuberculosis. J Biol Chem. 2012 Nov 2;287(45):37703-12. (PubMed)

Burmeister BT, Taglieri DM, Wang L, Carnegie GK. Src Homology 2 Domain-containing Phosphatase 2 (Shp2) Is a Component of the A-kinase-anchoring Protein (AKAP)-Lbc Complex and Is Inhibited by Protein Kinase A (PKA) under Pathological Hypertrophic Conditions in the Heart. J Biol Chem. 2012 Nov 23;287(48):40535-46. (PubMed)

Chalazonitis A, Kessler JA. Pleiotropic effects of the bone morphogenetic proteins on development of the enteric nervous system. Dev Neurobiol. 2012 Jun;72(6):843-56. Review. (PubMed)

Chaudhuri R, Carrillo O, Laughton CA, Orozco M. Application of Drug-Perturbed Essential Dynamics/Molecular Dynamics (ED/MD) to Virtual Screening and Rational Drug Design. J. Chem. Theory Comput. 2012 8 (7): 2204–2214. (ACS Publications)

Chaudhuri R, Lee H, Truong L, Torres J, Patel KK, Johnson ME. Identification of Non-Macrocyclic Small Molecule Inhibitors against the NS3/4A Serine Protease of Hepatitis C Virus through In-silico Screening. J Chem Inf Model. 2012 Aug 27;52(8):2245-56. (PubMed)

Chen S, Ni X, Krinsky BH, Zhang YE, Vibranovski MD, White KP, Long M. Reshaping of global gene expression networks and sex-biased gene expression by integration of a young gene. EMBO J. 2012 Apr 27;31(12):2798-809. (PubMed)

Chen S, Spletter M, Ni X, White KP, Luo L, Long M. Frequent recent origination of brain genes shaped the evolution of foraging behavior in Drosophila. Cell Rep. 2012 Feb 23;1(2):118-32. (PubMed)

Chen Y, Negre N, Li Q, Mieczkowska JO, Slattery M, Liu T, Zhang Y, Kim TK, He HH, Zieba J, Ruan Y, Bickel PJ, Myers RM, Wold BJ, White KP, Lieb JD, Liu XS. Systematic evaluation of factors influencing ChIP-seq fidelity. Nat Methods. 2012 Jun;9(6):609-14. (PubMed)

Chen Y, Ntai I, Ju KS, Unger M, Zamdborg L, Robinson SJ, Doroghazi JR, Labeda DP, Metcalf WW, Kelleher NL. A Proteomic Survey of Nonribosomal Peptide and Polyketide Biosynthesis in Actinobacteria. J Proteome Res. 2012 Jan 1;11(1):85-94. (PubMed)

Chen Y, Sheng R, Källberg M, Silkov A, Tun MP, Bhardwaj N, Kurilova S, Hall RA, Honig B, Lu H, Cho W. Genome-wide Functional Annotation of Dual-Specificity Protein- and Lipid-Binding Modules that Regulate Protein Interactions. Mol Cell. 2012 Apr 27;46(2):226-37. (PubMed)

Chernyak D, Gevorgyan V. Organocopper-Mediated Two-Component SN2’-Substitution Cascade Towards N-Fused Heterocycles. Chem Heterocycl Compd (N Y). 2012 Mar 1;47(12):1516-1526. (PubMed)

Chlon TM, Crispino JD. Combinatorial regulation of tissue specification by GATA and FOG factors. Development. 2012 Nov;139(21):3905-16. (PubMed)

Chlon TM, Doré LC, Crispino JD. Cofactor-Mediated Restriction of GATA-1 Chromatin Occupancy Coordinates Lineage-Specific Gene Expression. Mol Cell. Mol Cell. 2012 Aug 24;47(4):608-21. (PubMed)

Cho H, Balaji S, Sheikh AQ, Hurley JR, Tian YF, Collier JH, Crombleholme TM, Narmoneva DA. Regulation of endothelial cell activation and angiogenesis by injectable peptide nanofibers. Acta Biomater. 2012 Jan;8(1):154-64. (PubMed)

Chou SS, De M, Luo J, Rotello VM, Huang J, Dravid VP. Nanoscale graphene oxide (nGO) as artificial receptors: implications for biomolecular interactions and sensing. J Am Chem Soc. 2012 Oct 10;134(40):16725-33. (PubMed)

Comprehensive molecular portraits of human breast tumours. Cancer Genome Atlas Network. Collaborators (357 [White KP]). Nature. 2012 Oct 4;490(7418):61-70. (PubMed)

Compton PD, Kelleher NL. Spinning up mass spectrometry for whole protein complexes. Nat Methods. 2012 Nov;9(11):1065-6. (PubMed)

Cozen W, Li D, Best T, Van Den Berg DJ, Gourraud PA, Cortessis VK, Skol AD, Mack TM, Glaser SL, Weiss LM, Nathwani BN, Bhatia S, Schumacher FR, Edlund CK, Hwang AE, Slager SL, Fredericksen ZS, Strong LC, Habermann TM, Link BK, Cerhan JR, Robison LL, Conti DV, Onel K. A genome-wide meta-analysis of nodular sclerosis Hodgkin lymphoma identifies risk loci at 6p21.32. Blood. 2012 Jan 12;119(2):469-75. (PubMed)

Cui J, Chai DI, Miller C, Hao J, Thomas C, Wang J, Scheidt KA, Kozmin SA. Assembly of four diverse heterocyclic libraries enabled by prins cyclization, au-catalyzed enyne cycloisomerization, and automated amide synthesis. J Org Chem. 2012 Sep 7;77(17):7435-70. (PubMed)

Dam DH, Culver KS, Sisco PN, Odom TW. Shining light on nuclear-targeted therapy using gold nanostar constructs. Ther Deliv. 2012 Nov;3(11):1263-7. (PubMed)

Dam DH, Lee JH, Sisco PN, Co DT, Zhang M, Wasielewski MR, Odom TW. Direct observation of nanoparticle-cancer cell nucleus interactions. ACS Nano. 2012 Apr 24;6(4):3318-26. (PubMed)

Deng X, Sun F, Ji Q, Liang H, Missiakas D, Lan L, He C. Expression of multidrug resistance efflux pump gene norA is iron-responsive in Staphylococcus aureus. J Bacteriol. 2012 Apr;194(7):1753-62. (PubMed)

DeSario PA, Wu J, Grahm ME, Gray KA. Nanoscale structure of Ti1−xNbyO2 mixed-phase thin films: Distribution of crystal phase and dopants. Journal of Materials Research. 2012 Mar;27:944-950. (cambridge.org)

Ding L, Biswas S, Morton RE, Smith JD, Hay N, Byzova TV, Febbraio M, Podrez EA. Akt3 deficiency in macrophages promotes foam cell formation and atherosclerosis in mice. Cell Metab. 2012 Jun 6;15(6):861-72. (PubMed)

Doçi CL, Mankame TP, Langerman A, Ostler KR, Kanteti R, Best T, Onel K, Godley LA, Salgia R, Lingen MW. Characterization of NOL7 Gene Point Mutations, Promoter Methylation, and Protein Expression in Cervical Cancer. Int J Gynecol Pathol. 2012 Jan;31(1):15-24. (PubMed)

Doliba NM, Fenner D, Zelent B, Bass J, Sarabu R, Matschinsky FM. Repair of diverse diabetic defects of β-cells in man and mouse by pharmacological glucokinase activation. Diabetes Obes Metab. 2012 Oct;14 Suppl 3:109-19. (PubMed)

Dombeck DA, Reiser MB. Real neuroscience in virtual worlds. Curr Opin Neurobiol. 2012 Feb;22(1):3-10. (PubMed)

Doré LC, Chlon TM, Brown CD, White KP, Crispino JD. Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis. Blood. 2012 Apr 19;119(16):3724-33. (PubMed)

Duan Y, Learoyd J, Meliton AY, Leff AR, Zhu X. Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injury. Respir Res. 2012 Jan 18;13(1):4. (PubMed)

Dugas-Ford J, Rowell JJ, Ragsdale CW. Cell-type homologies and the origins of the neocortex. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16974-9. (PubMed)

ENCODE Project Consortium, Bernstein BE, Birney E, Dunham I, Green ED, Gunter C, Snyder M. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012 Sep 6;489(7414):57-74. (PubMed)

Feld DJ, Hsu HT, Eckermann AL, Meade TJ. Trinuclear ruthenium clusters as bivalent electrochemical probes for ligand-receptor binding interactions. Langmuir. 2012 Jan 10;28(1):939-49. (PubMed)

Fornelli L, Damoc E, Thomas PM, Kelleher NL, Aizikov K, Denisov E, Makarov A, Tsybin YO. Top-down analysis of monoclonal antibody IgG1 by electron transfer dissociation Orbitrap FTMS. Mol Cell Proteomics. 2012 Dec;11(12):1758-67. (PubMed)

Foshay KM, Looney TJ, Chari S, Mao FF, Lee JH, Zhang L, Fernandes CJ, Baker SW, Clift KL, Gaetz J, Di CG, Xiang AP, Lahn BT. Embryonic Stem Cells Induce Pluripotency in Somatic Cell Fusion through Biphasic Reprogramming. Mol Cell. 2012 Apr 27;46(2):159-70. (PubMed)

Frank SA, Rosner MR. Nonheritable Cellular Variability Accelerates the Evolutionary Processes of Cancer. PLoS Biol. 2012 10(4): e1001296. (PubMed)

Fu Y, He C. Nucleic acid modifications with epigenetic significance. Curr Opin Chem Biol. 2012 Dec;16(5-6):516-24. (PubMed)

Fullenkamp DE, Rivera JG, Gong YK, Lau KH, He L, Varshney R, Messersmith PB. Mussel-inspired silver-releasing antibacterial hydrogels. Biomaterials. 2012 May;33(15):3783-91. (PubMed)

Gaetz J, Clift KL, Fernandes CJ, Mao FF, Lee JH, Zhang L, Baker SW, Looney TJ, Foshay KM, Yu WH, Xiang AP, Lahn BT. Evidence for a critical role of gene occlusion in cell fate restriction. Cell Res. 2012 May;22(5):848-58.(PubMed)

Getts DR, Martin AJ, McCarthy DP, Terry RL, Hunter ZN, Yap WT, Getts MT, Pleiss M, Luo X, King NJ, Shea LD, Miller SD. Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis. Nat Biotechnol. 2012 Dec 7;30(12):1217-24. (PubMed)

Giam LR, Massich MD, Hao L, Shin Wong L, Mader CC, Mirkin CA. Scanning probe-enabled nanocombinatorics define the relationship between fibronectin feature size and stem cell fate. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4377-82. (PubMed)

Gil JE, Kim E, Kim IS, Ku B, Park WS, Oh BH, Ryu SH, Cho W, Heo WD. Phosphoinositides differentially regulate protrudin localization through the FYVE domain. J Biol Chem. 2012 Nov 30;287(49):41268-76. (PubMed)

Glasmacher E, Agrawal S, Chang AB, Murphy TL, Zeng W, Vander Lugt B, Khan AA, Ciofani M, Spooner CJ, Rutz S, Hackney J, Nurieva R, Escalante CR, Ouyang W, Littman DR, Murphy KM, Singh H. A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes. Science. 2012 Nov 16;338(6109):975-80. (PubMed)

Glotfelty LG, Hecht GA. Enteropathogenic E. coli effectors EspG1/G2 disrupt tight junctions: new roles and mechanisms. Ann N Y Acad Sci. 2012 Jul;1258(1):149-58. (PubMed)

Gordon KL, Ruvinsky I. Tempo and mode in evolution of transcriptional regulation. PLoS Genet. 2012 Jan;8(1):e1002432. (PubMed)

Grossman R, Rzhetsky A, Yu S. Global and Local Approach of Part-of-Speech Tagging on Large Text. AAAI 2012 Fall Symposium on Information Retrieval and Knowledge Discovery in Biomedical Text, 2012. (aaai.org)

Grossman RL, White KP. A Vision for a Biomedical Cloud. J Intern Med. 2012 Feb;271(2):122-30. doi: 10.1111/j.1365-2796.2011.02491.x. (PubMed)

Hadizadeh Yazdi N, Guet CC, Johnson RC, Marko JF. Variation of the folding and dynamics of the Escherichia coli chromosome with growth conditions. Mol Microbiol. 2012 Dec;86(6):1318-33. (PubMed)

Harney AS, Meade TJ, LaBonne C. Targeted inactivation of Snail family EMT regulatory factors by a Co(III)-Ebox conjugate. PLoS One. 2012;7(2):e32318. (PubMed)

Harney AS, Sole LB, Meade TJ. Kinetics and thermodynamics of irreversible inhibition of matrix metalloproteinase 2 by a Co(III) Schiff base complex. J Biol Inorg Chem. 2012 Aug;17(6):853-60. (PubMed)

Hause RJ Jr, Leung KK, Barkinge JL, Ciaccio MF, Chuu CP, Jones RB. Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors. PLoS One. 2012;7(9):e44471. (PubMed)

Hekman KE, Yu GY, Brown CD, Zhu H, Du X, Gervin K, Undlien DE, Peterson A, Stevanin G, Clark HB, Pulst SM, Bird TD, White KP, Gomez CM. A conserved eEF2 coding variant in SCA26 leads to loss of translational fidelity and increased susceptibility to proteostatic insult. Hum Mol Genet. 2012 Dec 15;21(26):5472-83. (PubMed)

Hesabi B, Danziger RS, Kotlo KU. Heterogeneous nuclear ribonucleoprotein A1 is a novel cellular target of atrial natriuretic peptide signaling in renal epithelial cells. Cell Signal. 2012 May;24(5):1100-8. (PubMed)

Hong BJ, An Z, Compton OC, Nguyen ST. Tunable biomolecular interaction and fluorescence quenching ability of graphene oxide: application to “turn-on” DNA sensing in biological media. Small. 2012 Aug 20;8(16):2469-76. (PubMed)

Hong BJ, Compton OC, An Z, Eryazici I, Nguyen ST. Successful stabilization of graphene oxide in electrolyte solutions: enhancement of biofunctionalization and cellular uptake. ACS Nano. 2012 Jan 24;6(1):63-73. (PubMed)

Hong HK, Huang W, Ramsey KM, Marcheva B, Bass J. Clock Genes and Energy Metabolism. Sleep Loss and Obesity. 2012 13-32. (SpringerLink)

Horvath TL, Abizaid A, Dietrich MO, Li Y, Takahashi JS, Bass J. Ghrelin-immunopositive hypothalamic neurons tie the circadian clock and visual system to the lateral hypothalamic arousal center. Molecular Metabolism. 2012 Dec; 1(1-2):79–85. (ScienceDirect)

Hu C, Nikolic D, Eggler AL, Mesecar AD, van Breemen RB. Screening for natural chemoprevention agents that modify human Keap1. Anal Biochem. 2012 Feb 1;421(1):108-14. (PubMed)

Jaeger J, Manu, Reinitz J. Drosophila blastoderm patterning. Curr Opin Genet Dev. 2012 Dec;22(6):533-41. (PubMed)

Jensen MP, Aryal BP, Gorman-Lewis D, Paunesku T, Lai B, Vogt S, Woloschak GE. Submicron hard X-ray fluorescence imaging of synthetic elements. Anal Chim Acta. 2012 Apr 13;722:21-8. (PubMed)

Jeon SM, Chandel NS, Hay N. AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress. Nature. 2012 May 9;485(7400):661-5. (PubMed)

Jeong DW, Cho H, Jones MB, Shatzkes K, Sun F, Ji Q, Liu Q, Peterson SN, He C, Bae T. The auxiliary protein complex SaePQ activates the phosphatase activity of sensor kinase SaeS in the SaeRS two-component system of Staphylococcus aureus. Mol Microbiol. 2012 Oct;86(2):331-48. (PubMed)

Jeyaraj D, Scheer FA, Ripperger JA, Haldar SM, Lu Y, Prosdocimo DA, Eapen SJ, Eapen BL, Cui Y, Mahabeleshwar GH, Lee HG, Smith MA, Casadesus G, Mintz EM, Sun H, Wang Y, Ramsey KM, Bass J, Shea SA, Albrecht U, Jain MK. Klf15 orchestrates circadian nitrogen homeostasis. Cell Metab. 2012 Mar 7;15(3):311-23. (PubMed)

Ji Q, Zhang L, Sun F, Deng X, Liang H, Bae T, He C. Staphylococcus aureus CymR is a new thiol-based oxidation-sensing regulator of stress resistance and oxidative response. J Biol Chem. 2012 Jun 15;287(25):21102-9. (PubMed)

Jia C, Hui L, Cao W, Lietz CB, Jiang X, Chen R, Catherman AD, Thomas PM, Ge Y, Kelleher NL, Li L. High-definition De Novo Sequencing of Crustacean Hyperglycemic Hormone (CHH)-family Neuropeptides. Mol Cell Proteomics. 2012 Dec;11(12):1951-64. (PubMed)

Jiang ZF, Xia F, Johnson KW, Bartom E, Tuteja JH, Stevens R, Grossman RL, Brumin M, White KP, Ghanim M. Genome sequences of the primary endosymbiont “Candidatus Portiera aleyrodidarum” in the whitefly Bemisia tabaci B and Q biotypes. J Bacteriol. 2012 Dec;194(23):6678-9. (PubMed)

Jimenez-Morales D, Liang J, Eisenberg B. Ionizable side chains at catalytic active sites of enzymes. Eur Biophys J. 2012 May;41(5):449-60. (PubMed)

Johansson S, Irgens H, Chudasama KK, Molnes J, Aerts J, Roque FS, Jonassen I, Levy S, Lima K, Knappskog PM, Bell GI, Molven A, Njølstad PR. Exome sequencing and genetic testing for MODY. PLoS One. 2012;7(5):e38050. (PubMed)

Källberg M, Bhardwaj N, Langlois R, Lu H. A structure-based protocol for learning the family-specific mechanisms of membrane-binding domains. Bioinformatics. 2012 Sep 15;28(18):i431-i437. (PubMed)

Kan L, Kitterman JA, Procissi D, Chakkalakal S, Peng CY, McGuire TL, Goldsby RE, Pignolo RJ, Shore EM, Kaplan FS, Kessler JA. CNS demyelination in fibrodysplasia ossificans progressiva. J Neurol. 2012 Dec;259(12):2644-55. (PubMed)

Kawasaki K, Porntaveetus T, Oommen S, Ghafoor S, Kawasaki M, Otsuka-Tanaka Y, Blackburn J, Kessler JA, Sharpe PT, Ohazama A. Bmp signalling in filiform tongue papillae development. Arch Oral Biol. 2012 Jun;57(6):805-13. (PubMed)

Kelleher NL. A cell-based approach to the human proteome project. J Am Soc Mass Spectrom. 2012 Oct;23(10):1617-24. (PubMed)

Kellie JF, Catherman AD, Durbin KR, Tran JC, Tipton JD, Norris JL, Witkowski CE, Thomas PM, Kelleher NL. Robust Analysis of the Yeast Proteome under 50 kDa by Molecular Weight-Based Fractionation and Top-Down Mass Spectrometry. Anal Chem. 2012 Jan 3;84(1):209-15. (PubMed)

Khodr CE, Pedapati J, Han Y, Bohn MC. Inclusion of a portion of the native SNCA 3’UTR reduces toxicity of human S129A SNCA on striatal-projecting dopamine neurons in rat substantia nigra. Dev Neurobiol. 2012 Jun;72(6):906-17. (PubMed)

Kilian KA, Mrksich M. Directing stem cell fate by controlling the affinity and density of ligand-receptor interactions at the biomaterials interface. Angew Chem Int Ed Engl. 2012 May 14;51(20):4891-5. (PubMed)

Kim Guisbert KS, Zhang Y, Flatow J, Hurtado S, Staley JP, Lin S, Sontheimer EJ. Meiosis-induced alterations in transcript architecture and noncoding RNA expression in S. cerevisiae. RNA. 2012 Jun;18(6):1142-53. (PubMed)

Kim H, Man HB, Saha B, Kopacz AM, Lee OS, Schatz GC, Ho D, Liu WK. Multiscale Simulation as a Framework for the Enhanced Design of Nanodiamond-Polyethylenimine-based Gene Delivery. J Phys Chem Lett. 2012 Dec 4;3(24):3791-3797. (PubMed)

Klaic L, Morimoto RI, Silverman RB. Celastrol Analogs as Inducers of the Heat Shock Response. Design and Synthesis of Affinity Probes for the Identification of Protein Targets. ACS Chem Biol. 2012 May 18;7(5):928-37. (PubMed)

Kohane IS, McMurry A, Weber G, MacFadden D, Rappaport L, Kunkel L, Bickel J, Wattanasin N, Spence S, Murphy S, Churchill S. The co-morbidity burden of children and young adults with autism spectrum disorders. PLoS One. 2012;7(4):e33224. (PubMed)

Kong BY, Bernhardt ML, Kim AM, O’Halloran TV, Woodruff TK. Zinc Maintains Prophase I Arrest in Mouse Oocytes Through Regulation of the MOS-MAPK Pathway. Biol Reprod. 2012 Jul 1;87(1):11. (PubMed)

Kouri FM, Jensen SA, Stegh AH. The role of Bcl-2 family proteins in therapy responses of malignant astrocytic gliomas: Bcl2L12 and beyond. ScientificWorldJournal. 2012;2012:838916. Review. (PubMed)

Krovi SA, Swindell EP, O’Halloran TV, Nguyen ST. Improved anti-proliferative effect of doxorubicin-containing polymer nanoparticles upon surface modification with cationic groups. J Mater Chem. 2012 Dec 28;22(48):25463-25470. (PubMed)

Kung VL, Khare S, Stehlik C, Bacon EM, Hughes AJ, Hauser AR. An rhs gene of Pseudomonas aeruginosa encodes a virulence protein that activates the inflammasome. Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1275-80. (PubMed)

Kuznetsov A, Gevorgyan V. General and practical one-pot synthesis of dihydrobenzosiloles from styrenes. Org Lett. 2012 Feb 3;14(3):914-7. (PubMed)

Landt SG, Marinov GK, Kundaje A, Kheradpour P, Pauli F, Batzoglou S, Bernstein BE, Bickel P, Brown JB, Cayting P, Chen Y, Desalvo G, Epstein C, Fisher-Aylor KI, Euskirchen G, Gerstein M, Gertz J, Hartemink AJ, Hoffman MM, Iyer VR, Jung YL, Karmakar S, Kellis M, Kharchenko PV, Li Q, Liu T, Liu XS, Ma L, Milosavljevic A, Myers RM, Park PJ, Pazin MJ, Perry MD, Raha D, Reddy TE, Rozowsky J, Shoresh N, Sidow A, Slattery M, Stamatoyannopoulos JA, Tolstorukov MY, White KP, Xi S, Farnham PJ, Lieb JD, Wold BJ, Snyder M. ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome Res. 2012 Sep;22(9):1813-31. (PubMed)

Langille MR, Personick ML, Zhang J, Mirkin CA. Defining rules for the shape evolution of gold nanoparticles. J Am Chem Soc. 2012 Sep 5;134(35):14542-54. (PubMed)

Launiere C, Gaskill M, Czaplewski G, Myung JH, Hong S, Eddington DT. Channel surface patterning of alternating biomimetic protein combinations for enhanced microfluidic tumor cell isolation. Anal Chem. 2012 May 1;84(9):4022-8. (PubMed)

Lee H, Torres J, Truong L, Chaudhuri R, Mittal A, Johnson ME. Reducing agents affect inhibitory activities of compounds: Results from multiple drug targets. Anal Biochem. 2012 Jan 18;423(1):46-53. (PubMed)

Lenz M, Thoresen T, Gardel M, Dinner A. Contractile Units in Disordered Actomyosin Bundles Arise from F-Actin Buckling. Phys Rev Lett. 2012 Jun;108(23). (PubMed)

Li Y, Lin L, Li Z, Ye X, Xiong K, Aryal B, Xu Z, Paroo Z, Liu Q, He C, Jin P. Iron Homeostasis Regulates the Activity of the MicroRNA Pathway through Poly(C)-Binding Protein 2. Cell Metab. 2012 Jun 6;15(6):895-904. (PubMed)

Li Y, Naveed H, Kachalo S, Xu LX, Liang J. Mechanisms of regulating cell topology in proliferating epithelia: impact of division plane, mechanical forces, and cell memory. PLoS One. 2012;7(8):e43108. (PubMed)

Li Z, Chernyak D, Gevorgyan V. Palladium-catalyzed carbonylative cyclization/arylation cascade for 2-aroylindolizine synthesis. Org Lett. 2012 Dec 7;14(23):6056-9. (PubMed)

Li Z, Gevorgyan V. One-pot arylative epoxidation of ketones by employing amphoteric bromoperfluoroarenes. Angew Chem Int Ed Engl. 2012 Jan 27;51(5):1225-7. (PubMed)

Liang H, Deng X, Ji Q, Sun F, Shen T, He C. Pseudomonas aeruginosa global regulator VqsR directly inhibits QscR to control quorum-sensing and virulence gene expression. J Bacteriol. 2012 Jun;194(12):3098-108. (PubMed)

Liao Y, Pourzal R, Stemmer P, Wimmer MA, Jacobs JJ, Fischer A, Marks LD. New insights into hard phases of CoCrMo metal-on-metal hip replacements. J Mech Behav Biomed Mater. 2012 Aug;12:39-49. (PubMed)

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